4-(3-Methyl-1,2,4-oxadiazol-5-yl)cyclohexane-1-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(3-Methyl-1,2,4-oxadiazol-5-yl)cyclohexane-1-carboxylic acid
• 英文别名: 4-(3-methyl-1,2,4-oxadiazol-5-yl)cyclohexane-1-carboxylic acid
• 化学式: C₁₀H₁₄N₂O₃
• 分子量: 210.23
• InChiKey: JEJDOHVBXJCSEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  76.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• LSD1 INHIBITOR AND PREPARATION METHOD AND APPLICATION THEREOF
  申请人：MEDSHINE DISCOVERY INC.

  公开号：US20200345700A1

  公开（公告）日：2020-11-05

  A cyclopropylamine compound as a lysine-specific demethylase 1 (LSD1) inhibitor. Particularly, the present invention relates to a compound represented by formula (I) and a pharmaceutically acceptable salt thereof. The present invention also provides an application of the same in preparing a drug for treating an LSD1-related disease.