铜(II)离子载体IV | 849629-03-4

• 物质功能分类: 分析化学 - 分析试剂 - 常用分析试剂
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 铜(II)离子载体IV
• 英文名称: Copper(II) Ionophore IV
• 英文别名: N,N-dicyclohexyl-2-[2-(dicyclohexylamino)-2-oxoethyl]sulfanylacetamide
• CAS: 849629-03-4
• 化学式: C₂₈H₄₈N₂O₂S
• 分子量: 476.8
• InChiKey: BUESTOLSNRTEQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  65.9
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• WGK Germany：
  3

文献信息

• MEANS FOR THE QUANTITATIVE DETERMINATION OF AN ANALYTE CONCENTRATION IN A PATIENT'S URINE SAMPLE
  申请人：Fuhrmann, Gerda Laura

  公开号：EP3537153A1

  公开（公告）日：2019-09-11

  The present invention relates to a single-use monoanalytical test-strip for the quantitative determination of an analyte in a patient's urine sample, and to a non-invasive point-of-care (POC) device for detecting deficiency and/or overload of an analyte in a patient's body. Furthermore, the present invention relates to a method for quantitatively determining the concentration of an analyte in a patient's urine sample and to a method of detecting deficiency and/or overload of an analyte in a patient's body. The test-strip comprises a substrate which either is electrically insulating or which has an electrically insulating layer applied thereon,- an electrode assembly applied on said substrate or on said electrically insulating layer, if present; and said electrode assembly comprises at least- one analyte-selective working electrode;- one reference electrode for said analyte-selective working electrode and an interface for electrically connecting said electrode assembly to a read out-meter device. Analytes are anions selected from halides, phopshates and sulfates or cations of alkali metals, of alkaline earth metals or of other metals.

  本发明涉及一种用于定量测定患者尿样中分析物的一次性单分析试纸，以及一种用于检测患者体内分析物缺乏和/或过量的非侵入性护理点（POC）设备。此外，本发明还涉及一种定量测定患者尿样中分析物浓度的方法，以及一种检测患者体内分析物缺乏和/或过量的方法。检测条包括一个基板，该基板是电绝缘的，或者在其上涂有电绝缘层；- 一个电极组件，如果有的话，涂在所述基板上或所述电绝缘层上；所述电极组件包括至少--一个分析物选择性工作电极；--一个用于所述分析物选择性工作电极的参比电极，以及一个用于将所述电极组件电连接到读出计装置的接口。分析物为阴离子，选自卤化物、磷酸盐和硫酸盐或碱金属、碱土金属或其他金属的阳离子。
• MEANS FOR THE QUANTITATIVE DETERMINATION OF CATIONIC ELECTROLYTE CONCENTRATION AND CREATININE CONCENTRATION AND OF THEIR RATIOS
  申请人：UriSalt GmbH

  公开号：EP3640633A1

  公开（公告）日：2020-04-22

  The present invention relates to a single-use test strip for the quantitative determination of a concentration of a cationic electrolyte which is not sodium, and of creatinine concentration, and for the subsequent determination of their ratio, and to a non-invasive point-of-care (POC) device for detecting a disorder of electrolyte balance in patient's body. Furthermore, the present invention relates to a method for simultaneously and quantitatively determining a cationic electrolyte concentration and creatinine concentration in a patient's urine sample and to a method of detecting a disorder of electrolyte balance in a patient's body.

  本发明涉及一种一次性试纸，用于定量测定非钠的阳离子电解质浓度和肌酐浓度，以及随后测定它们的比值，还涉及一种用于检测患者体内电解质平衡失调的非侵入性护理点（POC）设备。此外，本发明还涉及一种同时定量测定患者尿样中阳离子电解质浓度和肌酐浓度的方法，以及一种检测患者体内电解质平衡失调的方法。
• LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES
  申请人：Technical University of Denmark

  公开号：EP2453927B1

  公开（公告）日：2019-05-15
• ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS
  申请人：Technical University of Denmark

  公开号：EP2651447B1

  公开（公告）日：2018-08-29
• LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES
  申请人：Petersen Anncatrine Luisa

  公开号：US20120213698A1

  公开（公告）日：2012-08-23

  The present invention relates to a novel composition and method for loading delivery systems such as liposome compositions with radionuclides useful in targeted diagnostic and/or therapy of target site, such as cancerous tissue and, in general, pathological conditions associated with leaky blood vessels. The composition and methods of the invention find particular use in diagnosing and imaging cancerous tissue and, in general, pathological conditions associated with leaky blood vessels in a subject. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique. One specific aspect of the invention is directed to a method of producing nanoparticles with desired targeting properties for diagnostic and/or radio-therapeutic applications.