(1R,3R,4R)-3-[(1S)-1-acetamido-3-methylbutyl]-4-(1H-imidazol-5-yl)cyclopentane-1-carboxylic acid;hydrochloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: (1R,3R,4R)-3-[(1S)-1-acetamido-3-methylbutyl]-4-(1H-imidazol-5-yl)cyclopentane-1-carboxylic acid;hydrochloride
• 化学式: C16H26ClN3O3
• 分子量: 343.8
• InChiKey: BTGAPVONLFXRLK-FLOMBHTMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.58
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  95.1
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• US6518305B1
  申请人：——

  公开号：US6518305B1

  公开（公告）日：2003-02-11
• [EN] INHIBITORS OF NEURAMINIDASES<br/>[FR] INHIBITEURS DES NEURAMINIDASES
  申请人：ABBOTT LAB

  公开号：WO2001028979A2

  公开（公告）日：2001-04-26

  Disclosed are compounds of formula (I), (II) or (III) which are useful for inhibiting neuraminidases from disease-causing microorganisms, especially, influenza neuraminidase. Also disclosed are compositions and methods for preventing and treating diseases caused by microorganisms having a neuraminidase, processes for preparing the compounds and synthetic intermediates used in these processes.