(S)-4-(2-甲基丁氧基)-苯胺 | 112418-54-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: (S)-4-(2-甲基丁氧基)-苯胺
• 英文名称: (S)-(+)-4-(2-methylbutoxy)aniline
• 英文别名: (S)-4-(2-Methyl-butoxy)-phenylamine；4-[(2S)-2-methylbutoxy]aniline
• CAS: 112418-54-9
• 化学式: C₁₁H₁₇NO
• 分子量: 179.262
• InChiKey: DROCLXOXZQSXQJ-VIFPVBQESA-N

物化性质

• 沸点：
  287.7±13.0 °C(Predicted)
• 密度：
  0.984±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2922299090

反应信息

• 作为反应物：
  描述：

  4-formylphenyl 4-hexyloxybenzoate 、 (S)-4-(2-甲基丁氧基)-苯胺 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  末端双取代N-(4-苯甲酰氧基亚苄基)苯胺的制备及热性能

  摘要：

  N-[4-(4-n-烷氧基苯甲酰氧基)苯甲酰氧基]-4-(2-甲基丁氧基)苯胺(1)和N-[4-[4-(2-甲基丁氧基)苯甲酰氧基]苯亚甲基]-的同系物4-n-烷氧基苯胺 (2) 和 N-[4-(4-n-烷氧基苯甲酰氧基)-3-羟基亚苄基]-4-(2-甲基丁氧基)苯胺 (3) 其中 2-甲基丁氧基具有 S-构型，已经准备好了。除了胆甾型 (Ch) 和手性近晶 G (SG*) 相之外，系列 1 和系列 2 还形成手性近晶 C (SC*) 相，系列 3 形成 (SC*) 和 Ch 相。

  DOI：

  10.1246/bcsj.59.3965
• 作为产物：
  描述：

  对硝基苯酚 在 盐酸 、 铁粉 、 sodium hydride 作用下， 以 乙醇 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 6.0h， 生成 (S)-4-(2-甲基丁氧基)-苯胺
  参考文献：
  名称：

  Disc-Like Chiral Palladium and Platinum Complexes: Synthesis and Mesomorphic Properties

  摘要：

  DOI：

  10.1002/1099-0682(20011)2001:1<111::aid-ejic111>3.3.co;2-0

文献信息

• Effect of fluorocarbon chains on the mesomorphic properties of chiral imines and their complexes with copper(II)
  作者：Hale Ocak、Belkız Bilgin-Eran、Carsten Tschierske、Ute Baumeister、Gerhard Pelzl

  DOI：10.1039/b905104j

  日期：——

  The synthesis and mesomorphism of new chiral imine compounds incorporating a fluorocarbon chain which have calamitic molecular shape and their complexes with copper(II) are reported. The liquid crystalline properties were investigated using polarised optical microscopy, differential scanning calorimetry and X-ray diffraction. Imine compounds with a semifluorinated chain and a short chiral chain show chiral smectic mesophases with dramatically enhanced mesophase stabilities compared to the related hydrocarbon derivatives. In addition, the first examples of mesogenic chiral salicylaldiminate copper(II) complexes carrying semifluorinated alkyl chains at their peripheries have been synthesized and their liquid crystalline properties were investigated.

  报道了具有杆状分子形状的新型手性亚胺化合物及其与铜(II)配合物的合成和介晶作用。使用偏光光学显微镜、差示扫描量热法和X射线衍射研究了液晶特性。具有半氟化链和短手性链的亚胺化合物显示出手性近晶中间相，与相关烃衍生物相比，其中间相稳定性显着增强。此外，还合成了第一个在其外围带有半氟化烷基链的介晶手性水杨醛二胺铜(II)配合物，并研究了它们的液晶性质。
• Tailoring Chiral Discotic Liquid Crystals: Mesophase Engineering through Alternative Approaches and Chain Lengths
  作者：Madhusudan Maity、Indu Bala、Madhu Babu Kanakala、Santosh Prasad Gupta、C. V. Yelamaggad、Santanu Kumar Pal

  DOI：10.1002/asia.202300936

  日期：2024.1.15

  Hydrogen (H)-bonded discotic liquid crystals (DLCs) were synthesized through two distinct methods. The first approach introduced a chiral core connected via H-bonding to an achiral system, yielding supramolecular chirality within the columns. In the second method, an achiral core to a chiral system was introduced through H-bonding. Additionally, the peripheral alkyl chain lengths of the DLCs were changed

  通过两种不同的方法合成氢（H）键合盘状液晶（DLC）。第一种方法引入了通过氢键连接到非手性系统的手性核心，从而在柱内产生超分子手性。在第二种方法中，通过氢键将非手性核引入手性系统。此外，DLC 的外围烷基链长度发生变化，导致其内部结构发生温度诱导的转变。
• Study of mesomorphism, thermotropic properties and pitch in new chiral smectogenic imine compounds
  作者：Arif Nesrullajev、Belkıs Bilgin Eran

  DOI：10.1016/j.molliq.2015.05.010

  日期：2015.9

  We report the thermotropic, thermo-morphologic and structural properties of four homologs of (S)-5-alkyloxy-2-[4-(2-methylbutoxy)phenylimino}methyl]phenol liquid crystalline salicylaldimine compounds, which are firstly synthesized by our group. These compounds are monomorphic mesogens and exhibit the enantiotropic chiral smectic C* mesophase (SmC*). Typical textures of the SmC* mesophase and crystalline state of these new salicylaldimine compounds in large temperature intervals and in heterophase regions of the direct and reverse phase transitions have been investigated in detail. Temperature dependences of the pitch of chiral structure of the SmC* mesophase and the space period of chiral structure for both heating and cooling processes have been determined. (C) 2015 Elsevier B.V. All rights reserved.
• Chiral Smectic *C Mesogens Having Ester and Amide Central Linkages
  作者：R. C. Tandel、R. A. Vora

  DOI：10.1080/15421400801915027

  日期：2008.3.20

  Ten members of a chiral homologous series 4-(4'-n-alkoxy benzoyloxy benzoyl)4''- S- (+) 2-methyl butoxy anilides were synthesized in multiple step synthesis. Series exhibits chiral smectic *C and cholesteric mesophases. In this series, n-propyl to n-dodecyl derivatives exhibit smectic *C and cholesteric mesophases. n-Tetradecyl and n-hexadecyl derivatives exhibit only smectic *C phases. The plot of transition temperatures versus number of carbon atoms in alkoxy chain exhibits odd-even effect for cholestric-isotropic transition temperatures. The effect of amide linkage and chirality is discussed in detail. High-temperature cholestric phases exhibit vivid colors. Two compounds were analyzed by calorimetric study (C12 and C14) to confirm the transition temperatures of which was observed under polarizing microscope. The mesogenic behavior of the series compared with other series where amide central linkage differs in its position. The mesogenic thermal stability is compared with other related homologous series. The result indicates that amide linkage enhances smectic as well as cholesteric thermal stability but enhancement in smectic phase is much higher. Compounds are characterized by elemental analysis, IR spectral data, Mass spectral data, DSC, NMR, and microscopic study.
• Chiral Amplification in One-Dimensional Helical Nanostructures Self-Organized from Phenylethynyl Thiophene with Elaborated Long-Chain Dicarboxamides
  作者：Chun-Hsian Li、Kai-Chi Chang、Chia-Chen Tsou、Yikang Lan、Hsiao-Ching Yang、Shih-Sheng Sun

  DOI：10.1021/jo200573y

  日期：2011.7.15

  A bis-phenylethynyl thiophene derivative functionalized with long-chain pyridyl biscarboxamides displayed unique helical morphology in the xerogel form via nicely complementary intermolecular interactions. The helical nanostructures visualized by TEM and AFM remarkably matched well with the computational results. Supramolecular chirality can be amplified by coassembly of a chiral conductor to bias the helical arrangement.