2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
• 化学式: C30H20O14
• 分子量: 604.5
• InChiKey: MORXWKWPBZJOQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.98
• 重原子数：
  44
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  255
• 氢给体数：
  10
• 氢受体数：
  14

文献信息

• [EN] MUTANT SUCROSE PHOSPHORYLASES WITH IMPROVED GLYCOSYLATION ACTIVITY TOWARDS POLYPHENOLS<br/>[FR] SACCHAROSE PHOSPHORYLASES MUTANTES PRÉSENTANT UNE ACTIVITÉ DE GLYCOSYLATION AMÉLIORÉE ENVERS DES POLYPHÉNOLS
  申请人：UNIV GENT

  公开号：WO2016180818A1

  公开（公告）日：2016-11-17

  The present invention relates to glycosylating polyphenols via biocatalysis. More specifically the present invention discloses particular mutants of the thermostable sucrose phosphorylase derived from the microorganism Thermoanaerobacterium thermosaccharolyticum which efficiently glycosylate polyphenols such as resveratrol.

  本发明涉及通过生物催化作用对多酚进行糖基化。更具体地，本发明揭示了源自微生物热古菌糖原磷酸化酶的特定突变体，该突变体能够高效地糖基化多酚，例如白藜芦醇。
• Mutant sucrose phosphorylases with improved glycosylation activity towards polyphenols
  申请人：Universiteit Gent

  公开号：US10280442B2

  公开（公告）日：2019-05-07

  The present invention relates to glycosylating polyphenols via biocatalysis. More specifically the present invention discloses particular mutants of the thermostable sucrose phosphorylase derived from the microorganism Thermoanaerobacterium thermosaccharolyticum which efficiently glycosylate polyphenols such as resveratrol.

  本发明涉及通过生物催化使多酚糖基化。更具体地说，本发明公开了从微生物 Thermoanaerobacterium thermosaccharolyticum 中提取的热稳定性蔗糖磷酸化酶的特定突变体，这种突变体可以有效地糖基化白藜芦醇等多酚。
• BIOCATALYTIC PROCESS FOR THE PREPARATION OF 3-0-ACYL-FLAVONOIDS
  申请人：CONSIGLIO NAZIONALE DELLE RICERCHE

  公开号：EP1088094A1

  公开（公告）日：2001-04-04
• METHODS AND COMPOSITIONS FOR THERAPEUTIC TREATMENT
  申请人：Limerick BioPharma, Inc.

  公开号：EP2068865A2

  公开（公告）日：2009-06-17
• PHOSPHORYLATED PYRONE ANALOGS AND METHODS
  申请人：Limerick BioPharma, Inc.

  公开号：EP2182957A2

  公开（公告）日：2010-05-12