N-[2-(1-methylpyrazol-4-yl)phenyl]acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: N-[2-(1-methylpyrazol-4-yl)phenyl]acetamide
• 化学式: C₁₂H₁₃N₃O
• mdl: MFCD03645987
• 分子量: 215.25
• InChiKey: NWULYIMEEZNUGG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.166
• 拓扑面积：
  46.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• ANTI-FIBROTIC COMPOUNDS
  申请人：Certa Therapeutics Pty Ltd

  公开号：US20210246100A1

  公开（公告）日：2021-08-12

  Provided herein are anti-fibrotic compounds, in particular those of Formula (I), that inhibit the TGF-beta signaling pathway. Also provided are pharmaceutical compositions comprising the anti-fibrotic compounds, and methods of treating diseases or conditions associated with fibrosis, inflammation, and benign or malignant neoplastic diseases in a subject by administering a compound or composition described herein.