毒芹碱氢溴酸盐 | 637-49-0

• 分子结构分类: 有机化合物 - 生物碱及其衍生物
• 中文名称: 毒芹碱氢溴酸盐
• 中文别名: 氢溴酸-2-丙基六氢吡啶；氢溴酸毒芹碱；氢溴酸毒芹碱；氢溴酸-2-丙基六氢吡啶
• 英文名称: (S)-2-propyl-piperidine; hydrobromide
• 英文别名: (S)-2-Propyl-piperidin; Hydrobromid；Coniine hydrobromide；(2S)-2-propylpiperidine;hydrobromide
• CAS: 637-49-0
• 化学式: BrH*C₈H₁₇N
• 分子量: 208.142
• InChiKey: BWMPAYPMHXMUAF-QRPNPIFTSA-N

物化性质

• 熔点：
  211°

计算性质

• 辛醇/水分配系数(LogP)：
  2.51
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• Medical implant
  申请人：Boston Scientific Limited

  公开号：EP1803415A1

  公开（公告）日：2007-07-04

  A medical assembly includes an implant and an envelope at least partially enclosing a portion of the implant. The envelope may include a tongue to protect the implant, a scaffold to provide integrity to the envelope, a tab access to ease envelope withdrawal, and/or one or more discontinuities to ease envelope withdrawal.

  一种医疗组件包括植入体和至少部分封闭植入体部分的包膜。包膜可包括保护植入体的舌片、为包膜提供完整性的支架、便于抽出包膜的卡口和/或便于抽出包膜的一个或多个不连续面。
• A soft tissue anchor
  申请人：Boston Scientific Limited

  公开号：EP2543341A2

  公开（公告）日：2013-01-09

  The invention provides, in various embodiments, aspects of a soft tissue anchor which comprises an elongated body having an aperture in a proximal end for receiving a distal end of a delivery device and a plurality of barbs projecting radially from an external surface of the elongated body, wherein the elongated body is between 1 cm and 4 cm long.

  本发明在多个实施例中提供了一种软组织锚，它包括一个细长体，该细长体的近端有一个孔，用于接收输送装置的远端，细长体的外表面径向伸出多个倒钩，其中细长体的长度在 1 厘米到 4 厘米之间。
• Systems and devices for treating pelvic floor disorders
  申请人：Boston Scientific Limited

  公开号：EP2881082A2

  公开（公告）日：2015-06-10

  Disclosed are single-incision surgical procedures for treatment of urinary incontinence and/or pelvic floor disorders and related uses, devices, kits, and methods. Implants are also disclosed for use in the exemplary procedures. In certain embodiments, soft tissue anchors are used to anchor the surgical implants to obturator membranes of a patient.

  所公开的是用于治疗尿失禁和/或盆底障碍的单切口手术程序及相关用途、装置、套件和方法。还公开了用于示例手术的植入物。在某些实施例中，软组织锚用于将手术植入物固定到患者的闭孔膜上。
• Partially soluble implantable or insertable medical devices
  申请人：Boston Scientific Limited

  公开号：EP2932939A1

  公开（公告）日：2015-10-21

  A ureteral stent configured for at least partial implantation or insertion into a subject comprises a surface that is provided with a plurality of depressions that are at least partially filled with a solid soluble material. The depressions occupy more cross sectional area at the bladder end as compared to the kidney end of the stent.

  一种用于至少部分植入或插入受试者体内的输尿管支架包括一个表面，该表面上有多个凹陷，这些凹陷至少部分填充了固体可溶材料。与支架的肾脏端相比，这些凹陷在膀胱端占据更大的横截面积。
• Systems, methods and devices relating to implantable supportive slings
  申请人：Boston Scientific Scimed, Inc.

  公开号：US10219885B2

  公开（公告）日：2019-03-05

  The invention provides, in various embodiments, aspects of soft tissue anchors, adjustable length/tension slings, interconnects between slings and soft tissue anchors, delivery devices and systems for implanting supportive slings, and methods relating to anchoring, 5 adjusting and implanting supportive slings.

  本发明在各种实施方案中提供了软组织锚、可调节长度/张力吊衣、吊衣与软组织锚之间的互连装置、用于植入支撑吊衣的输送装置和系统，以及与锚定、调节和植入支撑吊衣有关的方法。