1-氰基-1-乙酸丙烯酯 | 22581-05-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 1-氰基-1-乙酸丙烯酯
• 英文名称: 2-Acetoxy-crotonsaeurenitril
• 英文别名: 1-Acetoxy-1-cyanpropen-(1)；1-Cyanoprop-1-enyl acetate
• CAS: 22581-05-1
• 化学式: C₆H₇NO₂
• 分子量: 125.127
• InChiKey: KDWLJRLMMTVSSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  50.1
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 危险等级：
  6.1(b)
• 海关编码：
  2926909090
• 包装等级：
  III
• 危险类别：
  6.1(b)
• 危险品运输编号：
  UN 2810

反应信息

• 作为反应物：
  描述：

  1-氰基-1-乙酸丙烯酯 、 环戊二烯 生成 3-methylbicyclo[2.2.1]heptan-2-one
  参考文献：
  名称：

  Racemization of camphor during .pi. sulfonation

  摘要：

  DOI：

  10.1021/ja01034a025
• 作为产物：
  描述：

  乙酸异丙烯酯 、 2-氧代丁腈 在 对甲苯磺酸 作用下， 生成 1-氰基-1-乙酸丙烯酯
  参考文献：
  名称：

  Racemization of camphor during .pi. sulfonation

  摘要：

  DOI：

  10.1021/ja01034a025

文献信息

• Acyl Cyanide. VI. The Synthesis of 1-Cyano-1-alkenyl Esters by the Reaction of Acyl Cyanides with Acid Chlorides. Synthesis and Mechanism
  作者：Akira Oku、Shingo Arita

  DOI：10.1246/bcsj.52.3337

  日期：1979.11

  The reactions of enolizable acyl cyanides (acetyl, propionyl, isobutyryl, and diphenylacetyl cyanide) with acid chlorides (acetyl, propionyl, benzoyl, p-nitrobenzoyl, diphenylcarbamoyl, and dimethy...

  可烯醇化的酰基氰（乙酰、丙酰基、异丁酰基和二苯乙酰氰）与酰基氯（乙酰、丙酰基、苯甲酰基、对硝基苯甲酰基、二苯基氨基甲酰基和二甲基...
• JPH1171329A
  申请人：——

  公开号：JPH1171329A

  公开（公告）日：1999-03-16
• C4-SPIRO-PYRROLIDINE ANTIVIRALS
  申请人：Or Yat Sun

  公开号：US20090022689A1

  公开（公告）日：2009-01-22

  The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention relates to novel antiviral compounds represented herein above, pharmaceutical compositions comprising such compounds, and methods for the treatment or prophylaxis of viral (particularly HCV) infection in a subject in need of such therapy with said compounds.
• Pyrrolidine Derivatives
  申请人：Qiu Yao-Ling

  公开号：US20090047247A1

  公开（公告）日：2009-02-19

  The present invention discloses compounds of formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention relates to novel antiviral compounds represented herein above, pharmaceutical compositions comprising such compounds, and methods for the treatment or prophylaxis of viral (particularly HCV) infection in a subject in need of such therapy with said compounds.
• ELECTROLYTE MEMBRANE, PRODUCTION METHOD THEREOF, AND FUEL CELL
  申请人：Kobayashi Motokazu

  公开号：US20090269646A1

  公开（公告）日：2009-10-29

  An electrolyte membrane with high durability is provided. The electrolyte membrane includes a porous film containing a nitrogen-containing heterocyclic ring or a cyano group, and a proton conductive component existing in pores of the porous film, wherein the proton conductive component includes a polymer compound containing at least a nitrogen-containing heterocyclic ring, a cyano group, and an acidic group in one molecule.