2'-(2,3-二羟基丙氧基)乙酰苯胺 | 63905-15-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2'-(2,3-二羟基丙氧基)乙酰苯胺
• 英文名称: N-(2-(2,3-dihydroxypropoxy)phenyl)acetamide
• 英文别名: o-Acetamidophenylglycerylether；acetic acid-[2-(2,3-dihydroxy-propoxy)-anilide]；Essigsaeure-[2-(2,3-dihydroxy-propoxy)-anilid]；2'-(2,3-Dihydroxypropoxy)acetanilide；N-[2-(2,3-dihydroxypropoxy)phenyl]acetamide
• CAS: 63905-15-7
• 化学式: C₁₁H₁₅NO₄
• 分子量: 225.244
• InChiKey: PKALPKIBIKMTCN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  78.8
• 氢给体数：
  3
• 氢受体数：
  4

安全信息

• 海关编码：
  2924299090

反应信息

• 作为反应物：
  描述：

  2'-(2,3-二羟基丙氧基)乙酰苯胺 在 盐酸 作用下， 生成 3-(2-氨基苯氧基)-1,2-丙烷二醇
  参考文献：
  名称：

  Beasley et al., Journal of Pharmacy and Pharmacology, 1957, vol. 9, p. 10,14

  摘要：

  DOI：
• 作为产物：
  描述：

  N1-[2-(环氧乙烷-2-基甲氧基)苯基]乙酰胺 在 甲酸 作用下， 反应 2.0h， 以77%的产率得到2'-(2,3-二羟基丙氧基)乙酰苯胺
  参考文献：
  名称：

  Polyaniline copolymers with solvent-mimic side chains

  摘要：

  ABSTRACTWe investigated new polyaniline copolymers with solvent‐mimic side chains for enhanced processability in various solvents. The solvent‐mimic side chains, benzyloxypropoxy (BOP), phenoxybutoxy (POB), and dihydroxypropoxy (DHP), were introduced into copolymers and used with nonpolar aromatic and polar alcoholic solvents, respectively. Compared to a polyaniline homopolymer, polyaniline copolymers with a small amount of side chains (<4 mol %) exhibit different physical properties, including film‐forming ability. This can be attributed to the solvent‐mimic side chains strongly interacting with the solvent and/or the polyaniline backbone. Especially, in nonpolar aromatic solvents, polyaniline copolymers with nonpolar aromatic BOP and POB side chains exhibit good film‐forming ability leading to high electrical conductivity, while the polyaniline homopolymer did not form a film. Therefore, introducing solvent‐mimic side chains in conducting polymers is a very attractive method of enhancing their processability and physical properties. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 1986–1995

  DOI：

  10.1002/pola.27648

文献信息

• Muscle-Relaxing Compounds Similar to 3-(o-Toloxy)-1,2-propanediol. II. Substituted Alkanediols¹
  作者：Harry L. Yale、Edward J. Pribyl、William Braker、Jack Bernstein、W. A. Lott

  DOI：10.1021/ja01164a108

  日期：1950.8
• Okamoto, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1954, vol. 74, p. 1069,1071
  作者：Okamoto

  DOI：——

  日期：——
• El-Said, Pharmazie, 1981, vol. 36, # 9, p. 604 - 606
  作者：El-Said

  DOI：——

  日期：——
• Beasley et al., Journal of Pharmacy and Pharmacology, 1957, vol. 9, p. 10,14
  作者：Beasley et al.

  DOI：——

  日期：——
• Polyaniline copolymers with solvent-mimic side chains
  作者：Seung-Chul Lee、Chan-Keun Jung、Hoon-Joo Jung、Suck-Hyun Lee、O.-P. Kwon

  DOI：10.1002/pola.27648

  日期：2015.9.1

  ABSTRACTWe investigated new polyaniline copolymers with solvent‐mimic side chains for enhanced processability in various solvents. The solvent‐mimic side chains, benzyloxypropoxy (BOP), phenoxybutoxy (POB), and dihydroxypropoxy (DHP), were introduced into copolymers and used with nonpolar aromatic and polar alcoholic solvents, respectively. Compared to a polyaniline homopolymer, polyaniline copolymers with a small amount of side chains (<4 mol %) exhibit different physical properties, including film‐forming ability. This can be attributed to the solvent‐mimic side chains strongly interacting with the solvent and/or the polyaniline backbone. Especially, in nonpolar aromatic solvents, polyaniline copolymers with nonpolar aromatic BOP and POB side chains exhibit good film‐forming ability leading to high electrical conductivity, while the polyaniline homopolymer did not form a film. Therefore, introducing solvent‐mimic side chains in conducting polymers is a very attractive method of enhancing their processability and physical properties. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 1986–1995