2,2'-[氧基双(4,1-亚苯基氧基亚甲基)]双环氧乙烷 | 19389-73-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,2'-[氧基双(4,1-亚苯基氧基亚甲基)]双环氧乙烷
• 英文名称: 4,4'-dihydroxydiphenyl ether diglycidyl ether
• 英文别名: Oxirane, 2,2'-[oxybis(4,1-phenyleneoxymethylene)]bis-；2-[[4-[4-(oxiran-2-ylmethoxy)phenoxy]phenoxy]methyl]oxirane
• CAS: 19389-73-2
• 化学式: C₁₈H₁₈O₅
• 分子量: 314.338
• InChiKey: OUMVQDFNHGJHOM-UHFFFAOYSA-N

物化性质

• 熔点：
  78-80 °C
• 沸点：
  469.2±30.0 °C(Predicted)
• 密度：
  1.264±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  23
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  52.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,2'-[氧基双(4,1-亚苯基氧基亚甲基)]双环氧乙烷 在 cerium(III) chloride heptahydrate 作用下， 以 乙腈 为溶剂， 反应 7.5h， 以86%的产率得到1-Chloro-3-[4-[4-(3-chloro-2-hydroxypropoxy)phenoxy]phenoxy]propan-2-ol
  参考文献：
  名称：

  [EN] BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE
  [FR] AGENTS THÉRAPEUTIQUES À BASE DE DÉRIVÉS DU BISPHÉNOL ET MÉTHODES POUR LEUR UTILISATION

  摘要：

  本发明提供具有公式（I）结构的化合物。这些化合物的用途包括治疗多种适应症，包括前列腺癌，同时还提供了涉及这些化合物的治疗方法。

  公开号：

  WO2011082488A1
• 作为产物：
  描述：

  4,4'-二羟基二苯醚 、 环氧氯丙烷 在 sodium hydride 、 水 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 21.17h， 以64%的产率得到2,2'-[氧基双(4,1-亚苯基氧基亚甲基)]双环氧乙烷
  参考文献：
  名称：

  [EN] BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE
  [FR] AGENTS THÉRAPEUTIQUES À BASE DE DÉRIVÉS DU BISPHÉNOL ET MÉTHODES POUR LEUR UTILISATION

  摘要：

  本发明提供具有公式（I）结构的化合物。这些化合物的用途包括治疗多种适应症，包括前列腺癌，同时还提供了涉及这些化合物的治疗方法。

  公开号：

  WO2011082488A1

文献信息

• Hydrocurable compositions containing epoxy and oxazolidine or oxazine groups, their use as or in coating and impregnating compositions and polymer containing such groups
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0033515A1

  公开（公告）日：1981-08-12

  Hydrocurable compositions are provided containing a plurality of epoxy groups and oxazolidine or oxazine groups which are storage stable for at least one month under anhydrous conditions. This stability is achieved by selecting oxazolidines or oxazines in which the 2-position carbon atom in the ring is free of hydrogen atoms and substituted by alkyl groups or an alkylene group which forms a hydrocarbon ring with that carbon atom. Upon exposure to moisture the oxa-groups ring open for reaction with the epoxy groups. The groups may be in the same or different components and thus the composition may comprise polyepoxide and a compound or polymer containing a plurality of the oxa-groups or a polymer containing both classes of groups. The latter polymer is one embodiment of the invention. The compositions may be used for coating, impregnating and adhesive purposes.

  本发明提供了含有多个环氧基团和噁唑烷或噁嗪基团的水固化组合物，这些组合物在无水条件下至少可稳定贮存一个月。这种稳定性是通过选择环中 2 位碳原子不含氢原子并被烷基或与该碳原子形成烃环的亚烷基取代的噁唑烷或噁嗪来实现的。当暴露在潮湿环境中时，羰基环会打开，与环氧基团发生反应。这些基团可以是相同或不同的组分，因此组合物可以包括聚环氧化物和含有多个氧杂基团的化合物或聚合物，或含有这两类基团的聚合物。后一种聚合物是本发明的一个实施方案。组合物可用于涂层、浸渍和粘合。
• Polyhydroxy polyether, process for its production and its use
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0199564A2

  公开（公告）日：1986-10-29

  A substantially linear polyhydroxy polyether, which (1) is composed substantially of aromatic units and aliphatic units, the proportion of the aromatic units being 50 to 98 mole % based on the total amount of the aromatic units and the aliphatic units, (2) has an intrinsic viscosity, measured at 25°C in o-chlorophenol, of from 0.3 to 2 dl/g, and (3) has a glass transition temperature of from 30 to 120°C. Two processes for preparing the polyhydroxy polyether are proposed. The polyhydroxy polyether is useful in applications which require gas-barrier property.

  一种基本线性的聚羟基聚醚，其(1)主要由芳香族单元和脂肪族单元组成，芳香族单元的比例为 50 至 98 摩尔%（基于芳香族单元和脂肪族单元的总量），(2)在 25°C 邻氯苯酚中测量的固有粘度为 0.3 至 2 分升/克，(3)玻璃化转变温度为 30 至 120°C。提出了制备聚羟基聚醚的两种工艺。这种聚羟基聚醚在需要气体阻隔性能的应用中非常有用。
• Process for the production of prepreg sheets
  申请人：International Business Machines Corporation

  公开号：EP0223061A2

  公开（公告）日：1987-05-27

  A process for the manufacture of void-free prepreg sheets formed by the impregnation of a reinforcing cloth (e.g. glass fibre cloth) with a solution of a thermosetting resin (e.g. epoxy resin). In the process, the reinforcing cloth is first prewetted with a liqid medium containing a solvent for the resin which has a viscosity less than that of the solution of thermosetting resin. The prewetted cloth is impregnated with a solution of the resin and then heated to remove the solvent and cure the resin. The prepreg sheets are used in the manufacture of printed circuit boards.

  一种通过用热固性树脂（如环氧树脂）溶液浸渍加固布（如玻璃纤维布）来制造无空隙预浸料板材的工艺。在此过程中，首先用含有树脂溶剂的液体介质预湿加固布，该介质的粘度小于热固性树脂溶液的粘度。将预湿布浸渍在树脂溶液中，然后加热以除去溶剂并固化树脂。预浸布可用于制造印刷电路板。
• Improved epoxide resin compositions and method
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0325058A1

  公开（公告）日：1989-07-26

  A method of improving epoxy resin compositions to provide a cured resin having improved glass transition temperature and toughness characteristics is provided. The method includes providing in an epoxy resin composition an effective amount of a substituted fluorene unit in the composition. The fluorene component acts as a chain extension agent and provides for increased glass transition temperature and less cross-link density. As a result, improved toughness occurs. In preferred applications a toughening agent is provided in the resin composition, to further enhance toughness. Preferred resin compositions, cured resins and methods of providing improved cured resins are also provided.

  本发明提供了一种改进环氧树脂组合物的方法，使固化树脂具有更好的玻璃化转变温度和韧性特性。 该方法包括在环氧树脂组合物中提供有效量的取代芴单元。 芴成分可作为链延伸剂，提高玻璃化温度，降低交联密度。 因此，韧性得到改善。 在优选应用中，树脂组合物中还添加了增韧剂，以进一步提高韧性。 此外，还提供了优选的树脂组合物、固化树脂以及提供改良固化树脂的方法。
• Method for selective plugging of a zone in a well
  申请人：CONOCO INC.

  公开号：EP0421611A1

  公开（公告）日：1991-04-10

  A mixture of a liquid epoxy material and a hardener is selec­tively placed in a well traversing a subterranean formation adjacent to a zone in said formation which is to be plugged. The mixture is dis­placed into the zone and allowed to harden, thereby plugging the zone. The process is particularly applicable to sealing off water production in a gravel-packed well. A positive displacement bailer may be effect­ively used to deliver the mixture to the zone. The epoxy material used is immiscible with and is heavier than the fluid in the well. The epoxy material is further characterized as being essentially free of solids and having a low viscosity at downhole conditions of temperature and pressure. The hardener has an activation temperature which is lower than the downhole formation temperature.

  将液态环氧材料和固化剂的混合物有选择地放入穿越地下地层的井中，井口邻近地层中需要堵塞的区域。将混合物移入该区域并使其硬化，从而堵塞该区域。该工艺尤其适用于封堵砾石包层井的产水。可以有效地使用容积式水瓢将混合物输送到该区域。所使用的环氧树脂材料与井内流体不相溶，且比井内流体重。环氧树脂材料的另一个特点是基本上不含固体，在井下温度和压力条件下粘度低。固化剂的活化温度低于井下地层温度。