2,3,4,5-四碘苯胺 | 135598-05-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,3,4,5-四碘苯胺
• 英文名称: 2,3,4,5-Tetraiodoaniline
• CAS: 135598-05-9
• 化学式: C₆H₃I₄N
• 分子量: 596.715
• InChiKey: ASISUNJVQFXFSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,3,4,5-四碘苯胺 在 亚硝酸异戊酯 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以56%的产率得到1,2,3,4-tetraiodobenzene
  参考文献：
  名称：

  Direct polyiodination of benzenesulfonic acid

  摘要：

  Direct aromatic polyiodination of benzenesulfonic acid (using I2 and H5IO6 in H2SO4 at room temperature) was performed to test the possible intermediacy of C6H5SO3H in the corresponding direct polyiodination of benzene to C6H2I4. The major product from C6H5SO3H was 3,4,5-triiodobenzenesulfonic acid (4). In contrast, no 4 was formed in the C6H6 reaction, showing that no significant sulfonation of C6H6 to C6H5SO3H occurred during benzene iodination. Compound 4 itself was shown to be inert under the reaction conditions. A pathway is proposed from C6H5SO3H to the other reaction products (C6I6, C6I5H, two C6I4H2 isomers, and 3,4,5-triiodophenol), which therefore avoids the intermediacy of 4.

  DOI：

  10.1021/jo00020a036
• 作为产物：
  描述：

  3,4,5-三碘苯胺 在 sodium acetate 、 一氯化碘 作用下， 以 溶剂黄146 为溶剂， 反应 2.5h， 以52%的产率得到2,3,4,5-四碘苯胺
  参考文献：
  名称：

  Direct polyiodination of benzenesulfonic acid

  摘要：

  Direct aromatic polyiodination of benzenesulfonic acid (using I2 and H5IO6 in H2SO4 at room temperature) was performed to test the possible intermediacy of C6H5SO3H in the corresponding direct polyiodination of benzene to C6H2I4. The major product from C6H5SO3H was 3,4,5-triiodobenzenesulfonic acid (4). In contrast, no 4 was formed in the C6H6 reaction, showing that no significant sulfonation of C6H6 to C6H5SO3H occurred during benzene iodination. Compound 4 itself was shown to be inert under the reaction conditions. A pathway is proposed from C6H5SO3H to the other reaction products (C6I6, C6I5H, two C6I4H2 isomers, and 3,4,5-triiodophenol), which therefore avoids the intermediacy of 4.

  DOI：

  10.1021/jo00020a036

文献信息

• IODO-FUNCTIONALIZED POLYMERS AS MASS SPECTROMETRY CALIBRANTS WITH A MASS-DEFECT OFFSET
  申请人：The Administrators of The Tulane Educational Fund

  公开号：EP3464463A1

  公开（公告）日：2019-04-10
• [EN] IODO-FUNCTIONALIZED POLYMERS AS MASS SPECTROMETRY CALIBRANTS WITH A MASS-DEFECT OFFSET<br/>[FR] POLYMÈRES IODO-FONCTIONNALISÉS COMME ÉTALONS DE SPECTROMÉTRIE DE MASSE PRÉSENTANT UN DÉCALAGE DE DÉFAUT DE MASSE
  申请人：THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND

  公开号：WO2017214036A1

  公开（公告）日：2017-12-14

  The present invention discloses novel calibrants containing between 1 and 5 iodine atoms and methods of making them using linear polymers, hyperbranched polymers, and biological polymers (including but not limited to proteins and peptides.) Methods of using the calibrants are also disclosed, such as mass spectrometry. The novel calibrants disclosed herein have a more cost-and time-efficient synthesis than other calibrants.
• Direct polyiodination of benzenesulfonic acid
  作者：Daniell Lewis Mattern、Xinhua Chen

  DOI：10.1021/jo00020a036

  日期：1991.9

  Direct aromatic polyiodination of benzenesulfonic acid (using I2 and H5IO6 in H2SO4 at room temperature) was performed to test the possible intermediacy of C6H5SO3H in the corresponding direct polyiodination of benzene to C6H2I4. The major product from C6H5SO3H was 3,4,5-triiodobenzenesulfonic acid (4). In contrast, no 4 was formed in the C6H6 reaction, showing that no significant sulfonation of C6H6 to C6H5SO3H occurred during benzene iodination. Compound 4 itself was shown to be inert under the reaction conditions. A pathway is proposed from C6H5SO3H to the other reaction products (C6I6, C6I5H, two C6I4H2 isomers, and 3,4,5-triiodophenol), which therefore avoids the intermediacy of 4.