2,3-二羟基丙基壬酸酯 | 3065-51-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 中文名称: 2,3-二羟基丙基壬酸酯
• 中文别名: 硫代脲,N-(氨基亚氨基甲基)-N'-甲基-N-(2-甲基苯基)-
• 英文名称: nonanoic acid 2,3-dihydroxypropaneyl ester
• 英文别名: nonanoic acid 2,3-dihydroxypropyl ester；2,3-dihydroxypropyl nonanoate；monoglycerol monononanoate；glycerol monononanoate；glyceryl pelargonate；1-nonanoyl-glycerol；glyceryl nonanoate；Monopelargonin；monononanin；2,3-Dihydroxypropyl nonan-1-oate
• CAS: 3065-51-8
• 化学式: C₁₂H₂₄O₄
• 分子量: 232.32
• InChiKey: BYPJBHDBVGRMOF-UHFFFAOYSA-N

物化性质

• 沸点：
  354.6±22.0 °C(Predicted)
• 密度：
  1.030±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2915900090

反应信息

• 作为产物：
  描述：

  壬酸 在 吡啶 、 2,2,2-三氯乙酰胺 、 1,1,1,3,3,3-六溴丙酮 、 三苯基膦 作用下， 以 二氯甲烷 、 1,2-二氯乙烷 为溶剂， 反应 1.5h， 生成 2,3-二羟基丙基壬酸酯
  参考文献：
  名称：

  利用六溴丙酮保护醇和醛，并在紫外线照射下使乙缩醛，缩酮和肟脱保护

  摘要：

  六溴丙酮（HBA）有效地用于保护醇和醛，以及对苯甲醛二甲基乙缩醛，Solketal以及其他缩醛和缩酮进行脱保护。在仅10分钟内，甘油的保护产生了90％的solketal，苯甲醛的保护得到了95％的苯甲醛二甲基乙缩醛。仅用2.5mol％的HBA，在15秒内在UV辐射下苯甲醛二甲基乙缩醛的脱保护得到超过90％的苯甲醛产率。HBA还成功用于脱氧。发现溶剂在这些反应的HBA效率中起着重要作用。

  DOI：

  10.1007/s11164-017-3168-0

文献信息

• Biphasic Palladium-Catalyzed Hydroesterification in a Polyol Phase: Selective Synthesis of Derived Monoesters
  作者：Romain Pruvost、Jérôme Boulanger、Bastien Léger、Anne Ponchel、Eric Monflier、Mathias Ibert、André Mortreux、Mathieu Sauthier

  DOI：10.1002/cssc.201403397

  日期：2015.6.22

  The palladium‐catalyzed hydroesterification reaction was performed with polyols and olefins in a liquid/liquid biphasic system composed of unreacted polyol on the one hand and apolar reaction products/organic solvents on the other hand. The palladium‐based catalyst was immobilized in the polyol phase thanks to the use of cationic triarylphosphines possessing pendent protonated amino groups in the acidic

  钯催化的加氢酯化反应是在多元醇和烯烃在液/液两相体系中进行的，该体系一方面由未反应的多元醇组成，另一方面由非极性反应产物/有机溶剂组成。由于使用了在酸性反应介质中具有侧翼质子化氨基的阳离子三芳基膦或磺化膦TPPTS（三苯基膦三钠-3,3'，3''-三磺酸盐），钯基催化剂被固定在多元醇相中。由于产物在催化相中的不溶性，该方法允许合成具有高选择性的多元醇的单酯，以及通过简单的倾析容易地分离催化剂。
• COMPOSITION CONTAINING A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND COSMETIC TREATMENT PROCESS
  申请人：CHODOROWSKI-KIMMES Sandrine

  公开号：US20100028277A1

  公开（公告）日：2010-02-04

  Composition containing, in a cosmetically or dermatologically acceptable medium, a compound that may be obtained by reaction between: an oil bearing at least one nucleophilic and/or electrophilic reactive function, and a junction group capable of establishing hydrogen bonds with one or more partner junction groups, the junction group bearing at least one reactive function capable of reacting with the reactive function borne by the oil, and also comprising at least one unit of formula (I) or (II):

  含有一种化合物的成分，可以通过以下反应获得：一个至少带有一个亲核和/或亲电反应功能的油，以及一个能够与一个或多个配对连接基建立氢键的连接基，该连接基至少带有一个能够与油所带反应功能发生反应的反应功能，并且还包括至少一个符合式(I)或(II)的单元的化妆品或皮肤学上可接受的介质。
• COSMETIC TREATMENT PROCESSES AND KIT
  申请人：Dublanchet Anne-Claude

  公开号：US20140155352A1

  公开（公告）日：2014-06-05

  The present invention relates to a cosmetic process for treating keratin materials, which can give them, especially in a long-lasting and reversible manner, interesting cosmetic properties; this process comprising the application to said materials: in a first stage, of a cosmetic composition comprising at least one graftable species, comprising at least one unit of formula (Ia): and in a second stage, of a cosmetic composition comprising at least one cosmetic active agent bearing at least one unit of formula (Ia): The invention also relates to a kit comprising said compositions.

  本发明涉及一种用于处理角蛋白材料的化妆品工艺，可以在长期和可逆的情况下赋予它们有趣的化妆品特性；该工艺包括向所述材料施加以下组成部分的应用：第一阶段，包括至少一种可接枝的物种的化妆品组合物，其中包括至少一个式(Ia)的单元；第二阶段，包括至少一种具有至少一个式(Ia)的化妆品活性剂的化妆品组合物：本发明还涉及包括所述组合物的套件。
• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, AND A PARTICULAR OIL
  申请人：Barba Claudia

  公开号：US20130022561A1

  公开（公告）日：2013-01-24

  The present invention relates to a cosmetic composition comprising, in a cosmetically acceptable medium, (i) a supramolecular compound that may be obtained by reaction between: at least one oil bearing at least one nucleophilic reactive function chosen from OH and NH 2 , and at least one junction group capable of establishing hydrogen bonds with one or more partner junction groups, each pairing of a junction group involving at least three hydrogen bonds, the said junction group bearing at least one isocyanate or imidazole reactive function capable of reacting with the reactive function borne by the oil, the said junction group also comprising at least one unit of formula (I) or (II): (I) (II) (ii) at least one oil, chosen from apolar hydrocarbon-based oils and silicone oils, (iii) at least one dyestuff. The invention also relates to a cosmetic treatment process comprising the application of the said composition.

  本发明涉及一种化妆品组合物，包括在一种化妆品可接受的介质中，(i) 一种超分子化合物，可以通过以下反应获得：至少含有一种带有至少一个亲核反应基团的油，所述亲核反应基团选择自OH和NH2，以及至少含有一个结合基团，能够与一个或多个配对结合基团建立氢键，每个结合基团的配对涉及至少三个氢键，所述结合基团带有至少一个异氰酸酯或咪唑反应基团，能够与油所带的反应基团反应，所述结合基团还包括至少一个式(I)或(II)的单元：(I) (II) (ii) 至少一种油，选择自非极性碳氢化合物基油和硅油，(iii) 至少一种染料。本发明还涉及一种化妆品处理过程，包括应用所述组合物。