6,6-dimethyl-morpholine-3-carboxylic acid (6-chloro-9H-β-carbolin-8-yl)-amide 、
2-bromo-1-(3,3-dimethyl-morpholin-4-yl)-ethanone 以
DMF (N,N-dimethyl-formamide) 为溶剂,
反应 3.0h,
生成 (S)-4-[2-(3,3-dimethyl-morpholin-4-yl)-2-oxo-ethyl]-6,6-dimethyl-morpholine-3-carboxylic acid (6-chloro-9H-β-carbolin-8-yl)-amide bis-hydrochloride salt