2-p-Anisidinoethanthiol | 5978-01-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-p-Anisidinoethanthiol
• 英文别名: 2-<4-Methoxy-anilino>-aethylmercaptan；2-p-anisidino-ethanethiol；2-p-Anisidino-aethanthiol；NoName_3114；2-(4-methoxyanilino)ethanethiol
• CAS: 5978-01-8
• 化学式: C₉H₁₃NOS
• 分子量: 183.274
• InChiKey: GMXROLILKSBBAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  22.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-p-Anisidinoethanthiol 在 三乙胺 、 三氯化磷 作用下， 以 正己烷 、 苯 为溶剂， 反应 2.5h， 以83.4%的产率得到2-Chloro-3-(4-methoxy-phenyl)-[1,3,2]thiazaphospholidine
  参考文献：
  名称：

  AN NMR STUDY OF THE REACTIONS OF CHLOROPHOSPHINES WITH AlC1₃. PHOSPHENIUM CATIONS FEATURING A S-P-N LINKAGE

  摘要：

  The N-P+-S phosphenium cations 1, 2 and 3 have been prepared by treatment of the respective precursor chlorophosphines 4, 5 and 6 with the stoichiometric quantity of AlCl3 in CH2Cl2 solution. The cations 3 are noteworthy that they are the first aliphatic phosphenium cations featuring a P-S bond. That the values of P-31 chemical shifts of phosphenium cations 3 are larger than those of aliphatic N-P+-N and N-P+-Cl cations characterize a relative inferior it-donor ability of RS group to R2N group and to Cl. The exo conformation of group at sulfur to dialkylamino group in 3 is proposed on the rare steric effect on P-31 chemical shifts of substitutes at sulfur.

  DOI：

  10.1080/10426509808035742
• 作为产物：
  描述：

  环硫乙烷 、 甲氧苯胺 以11%的产率得到2-p-Anisidinoethanthiol
  参考文献：
  名称：

  AN NMR STUDY OF THE REACTIONS OF CHLOROPHOSPHINES WITH AlC1₃. PHOSPHENIUM CATIONS FEATURING A S-P-N LINKAGE

  摘要：

  The N-P+-S phosphenium cations 1, 2 and 3 have been prepared by treatment of the respective precursor chlorophosphines 4, 5 and 6 with the stoichiometric quantity of AlCl3 in CH2Cl2 solution. The cations 3 are noteworthy that they are the first aliphatic phosphenium cations featuring a P-S bond. That the values of P-31 chemical shifts of phosphenium cations 3 are larger than those of aliphatic N-P+-N and N-P+-Cl cations characterize a relative inferior it-donor ability of RS group to R2N group and to Cl. The exo conformation of group at sulfur to dialkylamino group in 3 is proposed on the rare steric effect on P-31 chemical shifts of substitutes at sulfur.

  DOI：

  10.1080/10426509808035742

文献信息

• Ratschinskii et al., Zhurnal Obshchei Khimii, 1958, vol. 28, p. 2998,3001,3002;engl.Ausg.S.3027,3028,3030
  作者：Ratschinskii et al.

  DOI：——

  日期：——
• Jurew; German, Vestnik Moskovskogo Universiteta, 1956, vol. 11, # 1, p. 197
  作者：Jurew、German

  DOI：——

  日期：——
• Jur'ew; German, Zhurnal Obshchei Khimii, 1956, vol. 26, p. 550,552; engl. Ausg. S. 589, 591
  作者：Jur'ew、German

  DOI：——

  日期：——
• Jur'ew; Djatlowitzkaja, Zhurnal Obshchei Khimii, 1957, vol. 27, p. 2644,2645;engl.Ausg.S.2689
  作者：Jur'ew、Djatlowitzkaja

  DOI：——

  日期：——
• Jur'ew; Djatlowizkaja, Zhurnal Obshchei Khimii, 1957, vol. 27, p. 3148,3149; engl. Ausg. S. 3186, 3187
  作者：Jur'ew、Djatlowizkaja

  DOI：——

  日期：——