vinyl 4-methylbenzoate | 2653-44-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: vinyl 4-methylbenzoate
• 英文别名: Ethenyl 4-methylbenzoate
• CAS: 2653-44-3
• 化学式: C₁₀H₁₀O₂
• 分子量: 162.188
• InChiKey: HPHRYEFAPDIEIZ-UHFFFAOYSA-N

物化性质

• 沸点：
  103 °C(Press: 11.5 Torr)
• 密度：
  1.045±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  vinyl 4-methylbenzoate 在 吡啶 作用下， 以 四氢呋喃 为溶剂， 反应 6.0h， 生成 3-O-(4,4'-dimethoxytrityl)-5-O-toluoyl-1,2-dideoxy-D-ribose
  参考文献：
  名称：

  寡核苷酸合成中有用的无碱基位点前体的生物催化程序†

  摘要：

  通过发散的化学酶促合成，制备了无碱基位点的前体。几种生物催化剂和酰化研究了一种可提供适用于工业应用的实用且可扩展的绿色方法的化学剂。高度区域选择性的酰化和脱酰反应与1,2-二脱氧-D-核糖描述了产生优异产量的方法。快速，原子高效且方便地合成3-和5 - O -DMTr-1,2-二脱氧核糖 已经实现了图17和图19。这些化合物是制备亚磷酰胺所需的有用前体，亚磷酰胺的组装需要包含这些寡核苷酸的寡核苷酸。四氢呋喃 无基础病变。

  DOI：

  10.1039/c1ob05739a
• 作为产物：
  描述：

  乙酸乙烯酯 、 4-甲基苯甲酸酐 在 potassium tert-butylate 作用下， 以 四氢呋喃 为溶剂， 以41%的产率得到vinyl 4-methylbenzoate
  参考文献：
  名称：

  乙醇酯转移反应：乙烯基酯的简便合成

  摘要：

  精心设计了一种简单有效的无乙酸乙烯酯转移反应，乙酸乙烯酯的收率中等至高。该反应通过产生乙烯乙酸钾来实现，然后使其与脂族，芳基和杂芳基酸的均酸酐和混合酸酐反应，得到相应的乙烯基酯。然后通过进行分子内的Heck反应来探测由此生成的乙烯基酯的效用，从而以优异的收率得到异苯并呋喃-1（3 H）-one衍生物。

  DOI：

  10.1002/hlca.201300396

文献信息

• Cross-linking in the polymerization of vinyl benzoate and related compounds
  作者：George E. Ham、Eugene L. Ringwald

  DOI：10.1002/pol.1952.120080107

  日期：1952.1

  Branching and cross-linking are noted in emulsion and mass polymerizations involving vinyl benzoate and nuclearly substituted vinyl benzoates. A theory is proposed to account for this phenomenon based on free radical addition to the benzoate nucleus. Six new vinyl esters of substituted benzoic acids are described.

  在涉及苯甲酸乙烯酯和核取代的苯甲酸乙烯酯的乳液和本体聚合中注意到支化和交联。提出了一种理论来解释这种基于苯甲酸盐核中自由基加成的现象。描述了六种新的取代苯甲酸乙烯基酯。
• Reusable rhodium catalyst for the selective transvinylation of sp 2 -C linked carboxylic acid
  作者：Ruihang Jiang、Zhangpei Chen、Kun Zhan、Lei Liu、Junjie Zhou、Yongjian Ai、Shuang Li、Hongjie Bao、Ze'nan Hu、Li Qi、Jingting Wang、Hong-bin Sun

  DOI：10.1016/j.tetlet.2018.07.039

  日期：2018.8

  The vinyl benzoate derivatives were successfully synthesized by the transvinylation reactions that vinyl group transferred from vinyl acetate to aromatic carboxylic acids with the recoverable catalyst RhCl3·3H2O. This catalyst features air stable and tolerance of water, good reusable ability, meanwhile, shows high selectivity for aromatic carboxylic acid in the presence of phenolic hydroxyl. With this

  通过可回收的催化剂RhCl 3 ·3H 2 O通过乙酸乙烯酯将乙烯基转移至芳族羧酸的转乙烯基反应成功地合成了苯甲酸乙烯酯衍生物。该催化剂具有空气稳定性和耐水性，同时具有良好的可重复使用能力，显示出在酚羟基存在下对芳族羧酸具有高选择性。使用这种方法，可以以高达95％的收率生产各种苯甲酸乙烯酯衍生物。
• Copper(II)-Catalyzed Esterification of Arenecarboxylic Acids with Aryl- and Vinyl-Substituted Trimethoxysilanes
  作者：Jiang Cheng、Fang Luo、Changduo Pan、Pengcheng Qian

  DOI：10.1055/s-0029-1218759

  日期：2010.6

  In this paper, the copper(II)-catalyzed esterification reaction of arenecarboxylic acids with aryl- or vinyl-substituted trimethoxysilanes is described. A series of aryltrimethoxysilanes and arenecarboxylic acids worked well under this procedure, affording aryl benzoate derivatives in moderate to good yields. Notably, trimethoxy(vinyl)silanes also worked well under this procedure giving a facile and versatile method to access vinyl benzoate derivatives.

  本文描述了铜(II)催化的芳香族羧酸与芳基或乙烯基取代的三甲氧基硅烷的酯化反应。多种芳基三甲氧基硅烷和芳香族羧酸在该过程下表现良好，获得了中等到良好的芳基苯甲酸酯衍生物。值得注意的是，三甲氧基（乙烯基）硅烷在该过程中也表现出良好的效果，为获取乙烯基苯甲酸酯衍生物提供了一种简便且多样化的方法。
• Medical Resin Composition, Process For Producing Resin Composition and Process For Producing Molded Article
  申请人：Tanaka Jiro

  公开号：US20080200630A1

  公开（公告）日：2008-08-21

  A medical resin composition is produced by mixing a powder of a polymer (A) comprising repeating units having an ester group and a liquid of a vinyl ester monomer (B) having 6 or more carbon atoms to increase a viscosity and, according to demand, further performing a polymerization reaction. The thus produced resin composition inhibits leaching of irritative substances, reduces any adverse effects on the human body by endocrine disruptors, etc. and can be prepared with high operational efficiency. The resin composition is suitably used as a dental resin composition such as a tissue conditioner, a functional impression material, a lining material, a denture base material or a mouth piece material.

  一种医用树脂组合物的制备方法，包括将含有酯基重复单元的聚合物(A)粉末和含有6个或更多碳原子的乙烯酸酯单体(B)液体混合以增加粘度，并根据需要进一步进行聚合反应。由此制得的树脂组合物抑制刺激性物质的渗出，减少内分泌干扰物对人体的不良影响等，并且可以高效制备。该树脂组合物适用于牙科树脂组合物，例如组织调整剂、功能印模材料、填补材料、义齿基材料或口腔器材材料。
• Process for producing resin composition and process for producing molded article
  申请人：Tanaka Jiro

  公开号：US20100184921A1

  公开（公告）日：2010-07-22

  A medical resin composition is produced by mixing a powder of a polymer (A) comprising repeating units having an ester group and a liquid of a vinyl ester monomer (B) having 6 or more carbon atoms to increase a viscosity and, according to demand, further performing a polymerization reaction. The thus produced resin composition inhibits leaching of irritative substances, reduces any adverse effects on the human body by endocrine disruptors, etc. and can be prepared with high operational efficiency. The resin composition is suitably used as a dental resin composition such as a tissue conditioner, a functional impression material, a lining material, a denture base material or a mouth piece material.

  一种医用树脂组合物是通过混合聚合物(A)粉末和含有6个或更多碳原子的乙烯酸酯单体(B)的液体来增加粘度，并根据需要进一步进行聚合反应制备的。因此制得的树脂组合物抑制了刺激性物质的渗出，减少了内分泌干扰物对人体的不良影响等，并且可以高效制备。该树脂组合物适用于牙科树脂组合物，例如组织调节剂、功能印象材料、衬里材料、假牙基材料或口腔器材材料。