N-(N-benzoylthiocarbamoyl-glycyl)-glycine | 108676-88-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(N-benzoylthiocarbamoyl-glycyl)-glycine
• 英文别名: N-(N-Benzoylthiocarbamoyl-glycyl)-glycin；2-[[2-(Benzoylcarbamothioylamino)acetyl]amino]acetic acid
• CAS: 108676-88-6
• 化学式: C₁₂H₁₃N₃O₄S
• 分子量: 295.319
• InChiKey: QSSLGPRZSMJLOU-UHFFFAOYSA-N

物化性质

• 密度：
  1.405±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  140
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  双甘肽 、 苯甲酰基异硫氰酸酯 以 丙酮 为溶剂， 反应 3.0h， 以75%的产率得到N-(N-benzoylthiocarbamoyl-glycyl)-glycine
  参考文献：
  名称：

  SYNTHESIS AND BIOLOGICAL ACTIVITY OFN-AROYL-N′-SUBSTITUTED THIOUREA DERIVATIVES

  摘要：

  A series of N-aroyl-N ' -substituted thiourea derivatives have been prepared in good to excellent yields under the condition of solid-liquid phase transfer catalysis using polyethylene glycol-400(PEG-400) as the catalyst. The products have been characterized on the basis of analytical and spectral (IR and H-1 NMR) data. The promoting effects of some compounds on wheat growth have been tested preliminary.

  DOI：

  10.1081/scc-100105882

文献信息

• Degradative studies on peptides and proteins. Part I. A new method of stepwise degradation of peptides from the end bearing a free amino-group, employing N-acyldithiocarbamates
  作者：D. T. Elmore、P. A. Toseland

  DOI：10.1039/jr9540004533

  日期：——
• SYNTHESIS AND BIOLOGICAL ACTIVITY OF<i>N</i>-AROYL-<i>N</i>′-SUBSTITUTED THIOUREA DERIVATIVES
  作者：You-Ming Zhang、Tai-Bao Wei、Li-Ming Gao

  DOI：10.1081/scc-100105882

  日期：2001.1

  A series of N-aroyl-N ' -substituted thiourea derivatives have been prepared in good to excellent yields under the condition of solid-liquid phase transfer catalysis using polyethylene glycol-400(PEG-400) as the catalyst. The products have been characterized on the basis of analytical and spectral (IR and H-1 NMR) data. The promoting effects of some compounds on wheat growth have been tested preliminary.