N-chloro-propionanilide | 67097-66-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-chloro-propionanilide
• 英文别名: N-Chlor-propionanilid；N-Chlorpropionanilid；N-chloro-N-phenylpropanamide
• CAS: 67097-66-9
• 化学式: C₉H₁₀ClNO
• 分子量: 183.637
• InChiKey: RKLUHJIBJTXOQU-UHFFFAOYSA-N

物化性质

• 沸点：
  252.1±23.0 °C(Predicted)
• 密度：
  1.204±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-chloro-propionanilide 在 盐酸 作用下， 生成 N-(4-氯苯基)丙酰胺
  参考文献：
  名称：

  Chattaway, Journal of the Chemical Society, 1902, vol. 81, p. 639,641

  摘要：

  DOI：
• 作为产物：
  描述：

  N-苯基丙酰胺 在 sodium hypochlorite 、 乙醇 、 碳酸氢钠 作用下， 生成 N-chloro-propionanilide
  参考文献：
  名称：

  Chattaway, Journal of the Chemical Society, 1902, vol. 81, p. 639,641

  摘要：

  DOI：

文献信息

• Process for preparing 2-chlorosulfinyl-azetidinones
  申请人：ELI LILLY AND COMPANY

  公开号：EP0011370A1

  公开（公告）日：1980-05-28

  2-chlorosulfinyl-azetidin-4-ones of the formula wherein R is the residue of a carboxylic acid and R is a carboxylic acid protecting group, are prepared by reacting a penicillin sulfoxide ester of the formula wherein R and R1 are as defined above, with an N-chlorohalogenating agent, e.g. N-chlorophthalimide, in ar, inert organic solvent, e.g. toluene, under essentially anhydrous conditions in the presence of a cross-linked polyvinylpyridine polymer, e.g. poly-(4-vinylpyridine), said polymer containing between about 1 percent and about 10 percent cross-linking with e.g. divinylbenzene. The 2-chlorosulfinylazetidin-4-ones are used as intermediates for the preparation of 3-exomethylenecepham-4-carboxylic acid ester sulfoxides.

  式中的 2-氯亚磺酰基氮杂环丁烷-4-酮，其中 R 是羧酸残基，R 是羧酸保护基团。 式中 R 为羧酸残基、R 为羧酸保护基团的 2-氯亚磺酰基-氮杂环丁烷-4-酮，是由式中的青霉素亚砜酯与 N-氯卤化剂（如 N-氯酞酰亚胺）反应制备的。 其中 R 和 R1 如上定义，在 ar 惰性有机溶剂（如甲苯）中，在基本无水条件下，在交联聚乙烯吡啶聚合物（如聚-（4-乙烯基吡啶））存在下，与 N-氯卤化剂（如 N-氯邻苯二甲酰亚胺）反应，所述聚合物含有约 1%至约 10%的交联剂（如二乙烯基苯）。 2-chlorosulfinylazetidin-4-ones 可用作制备 3-exomethylenecepham-4-carboxylic acid ester sulfoxides 的中间体。
• Process for preparing 4-haloazetidin-2-ones
  申请人：ELI LILLY AND COMPANY

  公开号：EP0060120A1

  公开（公告）日：1982-09-15

  A process for preparing 4-haloazetidinones of the formu- which comprises reacting in an inert solvent at a temperature between about -20°C. and about 45°C. a 4-sulfino- azetidinone of the formula with at least one molar equivalent of a positive halogen reagent, where in the above formulas M is hydrogen, sodium or potassium, X is chloro, bromo, or iodo; R is a carboxy-protecting group; and R, is an acylamido or diacylamido group useful as intermediates for the preparation of β-lactam antibiotics.

  一种制备式-4-卤代氮杂环丁酮的工艺 式的 4-氨基磺氮杂环丁酮与至少一种摩尔当量的正卤素试剂反应。 式中 M 为氢、钠或钾，X 为氯、溴或碘；R 为羧基保护基团；R 为酰氨基或二酰基氨基，可用作制备 β-内酰胺类抗生素的中间体。
• Outdoor films stabilized against chemical attack
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0214507A2

  公开（公告）日：1987-03-18

  A new and improved environmental chemicals resistant light stabilizer package for thermoplastic substrates is disclosed. The stabilizer package comprises a specific oligomeric hindered amine light stabilizer with an ultra-­violet absorber in specified weight ratios. The stabilizer package is useful for stabilizing thermoplastic shaped arti­cles intended for outdoor use in areas where environmental chemicals such as agricultural chemicals, pool chemicals and the like are employed. In a preferred embodiment, a new and improved substantially colorless, light stable greenhouse film is provided which exhibits good weatherability and retention of physical properties even after repeated expo­sure to, for example, pesticides, herbicides and the like.

  本发明公开了一种用于热塑性基材的新型改进型耐环境化学品光稳定剂复合材料。该稳定剂包由特定低聚受阻胺光稳定剂和紫外线吸收剂按特定重量比组成。该稳定剂复合剂适用于在使用农用化学品、泳池化学品等环境化学品的地区稳定用于室外的热塑性成型物品。在一个优选的实施方案中，提供了一种新型和改进的基本无色、光稳定的温室薄膜，即使在反复接触杀虫剂、除草剂等物质后，仍能表现出良好的耐候性和物理性能保持性。
• Cleaning compositions and methods
  申请人：Reckitt Benckiser (UK) Limited

  公开号：EP1749880A1

  公开（公告）日：2007-02-07

  A cleaning composition comprises a water-in-oil emulsion which upon breakdown of the emulsion undergoes a physical change which is accompanied by an increase in the temperature of the composition. A method of cleaning a surface comprising the steps of applying to the surface the said cleaning composition and applying a force to the composition such that the emulsion breaks down and there is an increase in temperature of the composition.

  一种清洁组合物由油包水型乳液组成，乳液分解后会发生物理变化，同时组合物的温度升高。 一种清洁表面的方法，包括以下步骤：将上述清洁组合物涂在表面上，并对组合物施加一定的力，使乳液分解，组合物的温度升高。
• Improvements in or relating to cleaning
  申请人：Reckitt-Benckiser (UK) Limited

  公开号：EP2157161A1

  公开（公告）日：2010-02-24

  A liquid cleaning composition and a solid state catalyst are provided in combination. The solid state catalyst causes a chemical reaction in the liquid cleaning composition, when the liquid cleaning composition is brought into contact with it. The chemical reaction may increase the oxidising power of the liquid cleaning composition, or change its pH, or cause gas evolution, or release heat.

  液态清洁组合物与固态催化剂结合使用。当液体清洁组合物与固态催化剂接触时，固态催化剂会在液体清洁组合物中引起化学反应。化学反应可提高液体清洁组合物的氧化能力，或改变其 pH 值，或导致气体演变，或释放热量。