N,N’-bis(2-cyanophenyl)formamidine | 1257830-38-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N’-bis(2-cyanophenyl)formamidine
• 英文别名: N,N'-bis(2-cyanophenyl)imidoformamide；N,N'-bis(2-cyanophenyl)methanimidamide
• CAS: 1257830-38-8
• 化学式: C₁₅H₁₀N₄
• 分子量: 246.271
• InChiKey: YCJZBSXBPYOGMS-UHFFFAOYSA-N

物化性质

• 熔点：
  222-224 °C
• 沸点：
  478.7±55.0 °C(Predicted)
• 密度：
  1.11±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  72
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  原甲酸三乙酯 、 2-氨基苯甲腈 在 三氟乙酸 作用下， 以 Petroleum ether 为溶剂， 反应 18.0h， 以82%的产率得到N,N’-bis(2-cyanophenyl)formamidine
  参考文献：
  名称：

  The reaction of anthranilonitrile and triethylorthoformate revisited: formation of dimeric and trimeric species

  摘要：

  The reaction of anthranilonitrile and triethylorthoformate was performed under different experimental conditions, leading to substituted quinazolines, triazachrysenes or quinazolinyl-aminophenyl quinazolines. A mechanistic proposal is presented to rationalize the formation of these compounds. The fluorescence properties of the highly conjugated triazachrysene structures were studied and the fluorescence quantum yield for compounds 5 and 13 was comparable to that of pyrene. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2010.09.013

文献信息

• The reaction of anthranilonitrile and triethylorthoformate revisited: formation of dimeric and trimeric species
  作者：Elina Marinho、Rui Araújo、Fernanda Proença

  DOI：10.1016/j.tet.2010.09.013

  日期：2010.11

  The reaction of anthranilonitrile and triethylorthoformate was performed under different experimental conditions, leading to substituted quinazolines, triazachrysenes or quinazolinyl-aminophenyl quinazolines. A mechanistic proposal is presented to rationalize the formation of these compounds. The fluorescence properties of the highly conjugated triazachrysene structures were studied and the fluorescence quantum yield for compounds 5 and 13 was comparable to that of pyrene. (C) 2010 Elsevier Ltd. All rights reserved.
• Ultrasound promoted expeditious, catalyst-free and solvent-free approach for the synthesis of N,N′-diarylsubstituted formamidines at room temperature
  作者：Bashir Ahmad Dar、Syed Naseer Ahmad、Mohammad Arif Wagay、Altaf Hussain、Nisar Ahmad、Khursheed Ahmad Bhat、Mohammad Akbar Khuroo、Meena Sharma、Baldev Singh

  DOI：10.1016/j.tetlet.2013.06.131

  日期：2013.9

  An effortless and efficient protocol was developed for the synthesis of N,N'-diarylsubstituted formamidines under environment-friendly conditions. Ultrasonic energy was employed to obtain the desired products in excellent yields with high purity under solvent-free and catalyst-free conditions. Products were purified by the crystallization technique to avoid excess utilization of organic solvents. (C) 2013 Elsevier Ltd. All rights reserved.