1,1-bis(4-(piperidin-1-yl)phenyl)prop-2-yn-1-ol | 263026-73-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1-bis(4-(piperidin-1-yl)phenyl)prop-2-yn-1-ol
• 英文别名: 1,1-di(4-piperidinophenyl)prop-2-yn-1-ol；1,1-Di(4-piperidinophenyl)-2-propyn-1-ol；1,1-bis(4-piperidin-1-ylphenyl)prop-2-yn-1-ol
• CAS: 263026-73-9
• 化学式: C₂₅H₃₀N₂O
• 分子量: 374.526
• InChiKey: MRMFSXJNVAMJRI-UHFFFAOYSA-N

物化性质

• 沸点：
  565.7±50.0 °C(Predicted)
• 密度：
  1.140±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  26.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,1-bis(4-(piperidin-1-yl)phenyl)prop-2-yn-1-ol 、 2-萘酚 在 4-甲基苯磺酸吡啶 、 原甲酸三甲酯 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 4.0h， 以23.2%的产率得到1-[4-[3-(4-Piperidin-1-ylphenyl)benzo[f]chromen-3-yl]phenyl]piperidine
  参考文献：
  名称：

  [EN] PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM
  [FR] PHOTOCHROMES ET MATRICE POLYMÈRE PERMETTANT D'OBTENIR UN FILM DE GRADATION EFFICACE

  摘要：

  The present disclosure relates to a photochromic molecule and uses of said molecule. The present disclosure further relates to a method of preparing a film comprising said molecule. The present disclosure also relates to a film prepared using said molecule and a device comprising said molecule. Furthermore, the present disclosure relates to a method for synthesis of said molecule.

  公开号：

  WO2022148752A2
• 作为产物：
  描述：

  乙炔钠 、 bis[4-(piperidin-1-yl)phenyl]methanone 在 18-冠醚-6 作用下， 以 四氢呋喃 、 5,5-dimethyl-1,3-cyclohexadiene 为溶剂， 反应 168.0h， 生成 1,1-bis(4-(piperidin-1-yl)phenyl)prop-2-yn-1-ol
  参考文献：
  名称：

  Convenient synthesis of diarylpropargyl alcohols

  摘要：

  Reaction between benzophenones and sodium acetylide in THF in the presence of 18-crown-6 gives the corresponding diarylpropargyl alcohols.

  DOI：

  10.1016/j.mencom.2011.11.016

文献信息

• CHROMENE COMPOUND
  申请人：Tokuyama Corporation

  公开号：EP1184379B1

  公开（公告）日：2009-11-18
• GREY COLOURING PHOTOCHROMIC FUSED PYRANS
  申请人：JAMES ROBINSON LIMITED

  公开号：EP1117656B1

  公开（公告）日：2002-05-29
• US6387512B1
  申请人：——

  公开号：US6387512B1

  公开（公告）日：2002-05-14
• [EN] GREY COLOURING PHOTOCHROMIC FUSED PYRANS<br/>[FR] PYRANNES PHOTOCHROMES CONDENSES DONNANT UNE COLORATION GRISE
  申请人：JAMES ROBINSON LTD

  公开号：WO2000018755A1

  公开（公告）日：2000-04-06

  A photochromic grey colouring 2H-naphtho[1,2-b]pyran of formula (I) wherein R1 is selected from mono-, di- or poly-substituted aryl groups, mono-, di- or poly-substituted naphthyl groups and mono-, di- or poly-substituted heteroaryl groups, wherein at least one substituent is a nitrogen containing group, including amino, C¿1?-C20 and C6-C20 alkylamino, C1-C20 and C6-C20 dialkylamino, C2-C20 dialkenylamino, C2-C20 or C4-C20 di(polyalkenyl)amino, arylamino, diarylamino, C1-C20 alkylarylamino, tetra (C1-C10 linear or branched alkyl) guanidino and cyclic-amino groups and at least one of R?7 and R9¿, which may be the same or different, is selected from C¿1?-C20 N alkylamino C1-C20 N-alkylamido, C1-C20 N,N-dialkylamido, amido, nitro, amino, C1-C20 alkylamino, C1-C20 dialkylamino, C2-C20 dialkenylamino, C4-C20 di(polyalkenyl)amino, arylamino, diarylamino, C1-C20 alkylarylamino, or cyclicamino groups. The compounds may be combined with a polymeric host material such as plastic or glass to make a sunglass lens, an ophthalmic lens or a window. The compounds may also be included in an ink or a fuel.
• Convenient synthesis of diarylpropargyl alcohols
  作者：Valerii Z. Shirinian、Aleksei A. Shimkin、Artur K. Mailyan、Evgeniya S. Leonova、Mikhail M. Krayushkin

  DOI：10.1016/j.mencom.2011.11.016

  日期：2011.11

  Reaction between benzophenones and sodium acetylide in THF in the presence of 18-crown-6 gives the corresponding diarylpropargyl alcohols.