3-Methyl-Δ³-tetrahydrobenzaldehyd | 122425-33-6

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机氧化物
• 英文名称: 3-Methyl-Δ³-tetrahydrobenzaldehyd
• 英文别名: 5-Methylcyclohex-3-enecarbaldehyde；5-methylcyclohex-3-ene-1-carbaldehyde
• CAS: 122425-33-6
• 化学式: C₈H₁₂O
• 分子量: 124.183
• InChiKey: KYXMUABTWXREOG-UHFFFAOYSA-N

物化性质

• 沸点：
  171.3±29.0 °C(Predicted)
• 密度：
  0.983±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-Methyl-Δ³-tetrahydrobenzaldehyd 、 5-(5-Methyl-3-cyclohexen-1-yl)oxazolidine-2,4-dione 生成 5-(4-Methyl-3-cyclohexen-1-yl)oxazolidine-2,4-dione
  参考文献：
  名称：

  Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity

  摘要：

  低血糖噁唑烷-2,4-二酮，其在5位被（C.sub.5 -C.sub.9）不饱和单环、饱和双环或不饱和双环碳氢基团取代；它们的制备方法；以及它们在治疗高血糖哺乳动物中的应用方法。

  公开号：

  US04430337A1
• 作为产物：
  描述：

  间戊二烯 、 丙烯醛 在 1-methyl-3-butylimidazolium zinc chloride 作用下， 反应 24.0h， 生成 3-甲基-4-甲酰基环己烯 、 3-Methyl-Δ³-tetrahydrobenzaldehyd
  参考文献：
  名称：

  碳化钨催化原子经济级联反应选择性生产可再生对二甲苯

  摘要：

  碳化钨被用作对二甲苯的原子经济和可再生合成的催化剂，具有出色的选择性和4-甲基-3-环己烯-1-羰基醛（4-MCHCA）的产率。该中间体是两种容易获得的生物基丙烯醛和异戊二烯之间的狄尔斯-阿尔德反应的产物。我们的结果表明4-MCHCA通过不涉及外部氢源的分子内氢转移经历了新颖的脱氢芳香化-加氢脱氧级联过程，并且加氢脱氧是通过W 2上C = O键的直接解离而发生的C面。值得注意的是，该方法很容易适用于从生物基合成物中合成各种（多）甲基化的芳烃，因此有可能为有价值的芳族化合物提供不依赖石油的解决方案。

  DOI：

  10.1002/anie.201710074

文献信息

• COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION
  申请人：Ishida Kenya

  公开号：US20110117147A1

  公开（公告）日：2011-05-19

  The invention relates to a cooling sensation agent composition with a prolonged cool sensation effect comprising at least one compound selected from Formula (1) wherein each of A and B is a hydrogen atom or a hydrocarbon group which may have one or more substituents, in which A and B are not hydrogen atoms simultaneously, and the total number of carbon atoms in A and B is in the range of 6 to 18; and Formulae (2) to (4) wherein R1, R2, and R3 each represent a residue of an alcohol selected from 1-menthol, 1-isopulegol, 3-(1-menthoxy)propan-1,2-diol, 2-(1-menthoxy)ethan-1-ol, 3-(1-menthoxy)propan-1-ol, 2-methyl-3-(1-menthoxy)propan-1,2-diol and para-menthan-3,8-diol), and R4 represents a residue of a branched or straight-chain, cyclic or linear, or saturated or unsaturated alcohol having 6 to 18 carbon atoms that may have one or more aromatic rings that may have a condensed ring and substituent groups such as hydroxyl and ether groups; and R6 represents a hydrocarbon group having 11 to 19 carbon atoms that may be branched and contain one or more unsaturated bonds. The invention also relates to a sensory stimulation agent composition comprising the cooling sensation agent composition; a flavor or fragrance composition, a beverage or food product, a perfume or cosmetic product, a toiletry product, a daily utensil product or grocery, a fiber, a fiber product, a cloth or a medicine comprising the cooling sensation agent composition or the sensory stimulation agent composition; a production method thereof; a cooling processing method of a fiber, fiber product or a cloth, comprising compounding the cooling sensation agent composition or the sensory stimulation agent composition; and new compounds.
• US4430337A
  申请人：——

  公开号：US4430337A

  公开（公告）日：1984-02-07
• US8632792B2
  申请人：——

  公开号：US8632792B2

  公开（公告）日：2014-01-21
• [EN] COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION<br/>[FR] COMPOSITION D'AGENT DE SENSATION DE FRAÎCHEUR ET COMPOSITION D'AGENT DE STIMULATION SENSORIELLE
  申请人：TAKASAGO PERFUMERY CO LTD

  公开号：WO2009123355A2

  公开（公告）日：2009-10-08

  The invention relates to a cooling sensation agent composition with a prolonged cool sensation effect comprising at least one compound selected from Formula (1) wherein each of A and B is a hydrogen atom or a hydrocarbon group which may have one or more substituents, in which A and B are not hydrogen atoms simultaneously, and the total number of carbon atoms in A and B is in the range of 6 to 18; and Formulae (2) to (4) wherein R1, R2, and R3 each represent a residue of an alcohol selected from l-menthol, l-isopulegol, 3-(l-menthoxy)propan-1,2-diol, 2-(l-menthoxy)ethan-1-ol, 3-(l-menthoxy)propan-1-ol, 2-methyl-3-(l-menthoxy)propan-1,2-diol and para-menthan-3,8-diol), and R4 represents a residue of a branched or straight-chain, cyclic or linear, or saturated or unsaturated alcohol having 6 to 18 carbon atoms that may have one or more aromatic rings that may have a condensed ring and substituent groups such as hydroxyl and ether groups; and R6 represents a hydrocarbon group having 11 to 19 carbon atoms that may be branched and contain one or more unsaturated bonds. The invention also relates to a sensory stimulation agent composition comprising the cooling sensation agent composition; a flavor or fragrance composition, a beverage or food product, a perfume or cosmetic product, a toiletry product, a daily utensil product or grocery, a fiber, a fiber product, a cloth or a medicine comprising the cooling sensation agent composition or the sensory stimulation agent composition; a production method thereof; a cooling processing method of a fiber, fiber product or a cloth, comprising compounding the cooling sensation agent composition or the sensory stimulation agent composition; and new compounds.