(1,2-dimethylpropoxy)benzene | 62338-26-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (1,2-dimethylpropoxy)benzene
• 英文别名: Benzene, (1,2-dimethylpropoxy)-；3-methylbutan-2-yloxybenzene
• CAS: 62338-26-5
• 化学式: C₁₁H₁₆O
• 分子量: 164.247
• InChiKey: NSSBMHJAFSJCBM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-甲基-2-丁醇 、 苯酚 在 偶氮二羰基二吗啉 、 三丁基膦 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 以51%的产率得到(1,2-dimethylpropoxy)benzene
  参考文献：
  名称：

  Azodicarbonyl dimorpholide (ADDM): an effective, versatile, and water-soluble Mitsunobu reagent

  摘要：

  One of the caveats of the Mitsunobu reaction is the often difficult and laborious purification of the reaction mixture. Herein, we show that azodicarbonyl dimorpholide (ADDM) is an effective and versatile Mitsunobu reagent, which, along with its reduced form ADDM-H-2, may be removed from the reaction mixture by a simple aqueous extraction. Furthermore, we demonstrate that the isolated ADDM-H-2 may be re-oxidized with silver(I) oxide to regenerate ADDM. Finally, a chromatography-free Mitsunobu reaction is presented. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.06.049

文献信息

• HETEROCYCLIC CETP INHIBITORS
  申请人：Salvati E. Mark

  公开号：US20070161685A1

  公开（公告）日：2007-07-12

  Compounds of formula Ia and Ib wherein A, B, C and R 1 are described herein.

  式Ia和Ib的化合物 其中A、B、C和R1 如本文所述。
• DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS
  申请人：Novira Therapeutics, Inc.

  公开号：US20160185777A1

  公开（公告）日：2016-06-30

  Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

  本文提供了一些用于治疗HBV感染的化合物，以及它们的药物组合物和在患有该病的受试者中抑制、抑制或预防HBV感染的方法。
• Substituted Fused Pyrimidinones and Dihydropyrimidinones
  申请人：FRACKENPOHL Jens

  公开号：US20120157306A1

  公开（公告）日：2012-06-21

  The use of substituted fused pyrimidinones and dihydropyrimidinones of the formula (I) or salts thereof where the radicals of the formula (I) are each as defined in the description, for enhancing stress tolerance in plants to abiotic stress, and for invigorating plant growth and/or for increasing plant yield.

  使用公式（I）中定义的基团的取代融合嘧啶酮和二氢嘧啶酮或其盐，用于增强植物对非生物胁迫的耐受性，激发植物生长和/或增加植物产量。
• SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES
  申请人：BAYER INTELLECTUAL PROPERTY GMBH

  公开号：US20150173359A1

  公开（公告）日：2015-06-25

  The use of substituted fused pyrimidinones and dihydropyrimidinones of the formula (I) or salts thereof where the radicals of the formula (I) are each as defined in the description, for enhancing stress tolerance in plants to abiotic stress, and for invigorating plant growth and/or for increasing plant yield.

  使用式(I)中的替代融合嘧啶酮和二氢嘧啶酮或其盐，其中式(I)的基团如描述中所定义，用于增强植物对非生物胁迫的耐受性，促进植物生长和/或增加植物产量。
• Derivatives and methods of treating hepatitis B infections
  申请人：Novira Therapeutics, Inc.

  公开号：US10189835B2

  公开（公告）日：2019-01-29

  Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

  本文提供了用于治疗有需要的受试者 HBV 感染的化合物、其药物组合物以及抑制、抑制或预防受试者 HBV 感染的方法。