triazole-3-diazonium nitrate | 59104-93-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: triazole-3-diazonium nitrate
• 英文别名: 1H-1,2,4-triazole-5-diazonium;nitrate
• CAS: 59104-93-7
• 化学式: C₂H₂N₅*NO₃
• 分子量: 158.076
• InChiKey: QGIWDQJJJXQMEX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.05
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  133
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  triazole-3-diazonium nitrate 生成 (1H-[1,2,4]triazol-3-ylhydrazono)-malonic acid diethyl ester
  参考文献：
  名称：

  TENNANT G.; VEVERS R. J. S., J. CHEM. SOC. PERKIN TRANS., PART 1 , 1976, NO 4, 421-428

  摘要：

  DOI：

文献信息

• Synthesis and characterization of new pyrazole-based thiazoles
  作者：Abdou O. Abdelhamid、Sobhi M. Gomha

  DOI：10.1080/00397911.2017.1330961

  日期：2017.8.3

  ABSTRACT A series of new 5-(heteroaryldiazenyl)thiazole incorporating pyrazole moiety have been synthesized through coupling of the thiazole with the appropriate heteroaryldiazonium salts. The newly synthesized compounds were characterized by elemental analysis, spectroscopic (IR, 1H NMR, and Mass) data, and alternative synthesis whenever possible. GRAPHICAL ABSTRACT

  摘要 通过将噻唑与合适的杂芳基重氮盐偶联，合成了一系列新的含有吡唑部分的 5-(杂芳基二氮烯基)噻唑。新合成的化合物通过元素分析、光谱（IR、1H NMR 和质谱）数据以及可能的替代合成进行表征。图形概要
• Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor
  作者：Sobhi MOHAMED GOMHA、Ahmad SAMI SHAWALI、Abdou OSMAN ABDELHAMID

  DOI：10.3906/kim-1311-12

  日期：——

  A new, less expensive, solvent-free procedure was developed for the synthesis of some new derivatives of various fused heterocyclic ring systems, namely azolopyridazine, azolotriazine, azinotriazine, thienopyridine, and pyrazolopyridine. The structures of the products prepared were established by their spectral data and elemental analyses. Eight compounds were evaluated for their in vitro antimicrobial activity. Some of the tested compounds exhibited moderate to significant antibacterial and antifungal activities.

  开发了一种新的、更经济的无溶剂方法，用于合成各种融合杂环系统的若干新型衍生物，包括吖啶并嘧嗪、吖啶并三嗪、氰基三嗪、噻吩并吡啶和吡唑并吡啶。通过其光谱数据和元素分析确定了制备产物的结构。对八种化合物进行了体外抗菌活性评估，其中一些测试化合物显示出中等到显著的抗细菌和抗真菌活性。
• Synthesis of New Pyrazolo[5,1-c]triazine, Triazolo[5,1-c]triazine, Triazino[4,3-b]indazole and Benzimidazo[2,1-c]triazine Derivatives Incorporating Chromen-2-one Moiety
  作者：Mohamed A. Khalil、Samia M. Sayed、Mohamed A. Raslan

  DOI：10.5012/jkcs.2013.57.5.612

  日期：2013.10.20

  The versatile, hitherto unreported 3-(4-(2-phenyldiazenyl)-2-oxo-2H-chromen-3-yl)-3-oxopropanenitrile 3 was prepared by two convenient routes: either by the reaction of ethyl 4-(2-phenyldiazenyl)-2-oxo-2H-chromen-3-carboxylate 2 with acetonitrile in the presence of sodium hydride or by treatment of 4-(2-phenyldiazenyl)-3-(2-bromoacetyl)-2H-chromen-2- one 5 with potassium cyanide. Reaction of 3 with

  通用的，迄今未报道的3-（4-（2-苯基二氮烯基）-2-oxo-2H-chromen-3-yl）-3-氧代丙烷腈3通过两种便捷的途径制备：要么通过乙基4-（2氢化钠存在下或通过处理4-（2-苯基二氮烯基）-3-（2-溴乙酰基）-2H-铬-2-一5与氰化钾。3与杂环重氮盐6、7、14和17的反应提供了相应的8、9、15和18。后者经过分子内环化成相应的吡唑并（5,1-
• Synthesis and the reactions of trifluoromethylated 1,2,3-triketones 2-(het)arylhydrazones and 4,7-dihydroazolo[5,1-c]triazines
  作者：O.G. Khudina、E.V. Shchegol’kov、Ya.V. Burgart、M.I. Kodess、O.N. Kazheva、A.N. Chekhlov、G.V. Shilov、O.A. Dyachenko、V.I. Saloutin、O.N. Chupakhin

  DOI：10.1016/j.jfluchem.2005.06.001

  日期：2005.8

  1-c]triazines react regio-selectively with methyl hydrazine and phenyl hydrazine to form 3-CF3-pyrazoles. The long-range coupling constants (JF-H) of 1-methylpyrazoles and the chemical shifts of trifluoromethyl groups in the 19F NMR spectra can be used for the determination of regio-isomeric structures of mono(trifluoromethyl)-substituted pyrazoles. 2-(Het)arylhydrazones and 4,7-dihydroazolo[5,1-c]triazines

  三氟甲基化的1,3-二酮与氯化（杂）芳基重氮偶合，主要导致形成1,2,3-三酮2-（杂）芳基azo，同时在杂环的α-位使用带有NH-基的杂芳胺因为重氮组分由于在三氟乙酰基片段上的环化作用而产生了4,7-二氢偶氮[5,1- c ]三嗪。三氟甲基化的1,2,3-三酮2-（杂）芳基hydr和7-羟基-4,7-二氢偶氮[5,1- c ]三嗪区域选择性地与甲基肼和苯基肼反应形成3-CF 3-吡唑。1-甲基吡唑的长程耦合常数（J F-H）和19中三氟甲基的化学位移F NMR光谱可用于确定单（三氟甲基）取代的吡唑的区域异构结构。具有两个三氟甲基取代基的2-（Het）芳基hydr和4,7-二氢唑并[5,1- c ]三嗪在与肼的反应中提供顺式和反式-偶氮吡唑的混合物。
• Convenient and Efficient Method for Synthesis of Bis-Hetaryl Ketones and Evaluation of Their Antimicrobial Activity
  作者：Abdou O. Abdelhamid、Sobhi M. Gomha、Waleed A. M. A. El-Enany

  DOI：10.1002/jhet.3415

  日期：2019.2

  Sodium 1‐aryl‐3‐(3‐(ethoxycarbonyl)‐5‐methyl‐1H‐pyrazol‐4‐yl)‐3‐oxoprop‐1‐en‐1‐olate was used as precursor for the preparation of some novel derivatives of various fused azolotriazine ring systems via coupling reactions with hetaryldiazonium salts. Hydrazinolysis of the latter products yielded the corresponding pyrazolopyridazine derivatives. The structures of the products were established by their

  1-芳基-3-（3-（乙氧基羰基）-5-甲基-1 H-吡唑-4-基）-3-氧代丙-1-烯-1-油酸钠被用作制备某些新型衍生物的前体通过与杂芳基重氮盐的偶联反应制备各种稠合的三唑三嗪环系统。后一种产物的水合肼解反应产生相应的吡唑并哒嗪衍生物。产品的结构是通过其光谱数据和元素分析确定的。还评估了一些新产品的抗菌和抗真菌活性。