EV06062 | 1416563-05-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: EV06062
• 英文别名: 4-Pentan-3-yloxychromen-2-one；4-pentan-3-yloxychromen-2-one
• CAS: 1416563-05-7
• 化学式: C₁₄H₁₆O₃
• 分子量: 232.279
• InChiKey: NMJIZIPXJPMGQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-羟基香豆素 、 3-戊醇 在 三苯基膦 、 偶氮二甲酸二乙酯 作用下， 以 四氢呋喃 为溶剂， 以87%的产率得到EV06062
  参考文献：
  名称：

  Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use

  摘要：

  本发明涉及新型香豆素衍生物、包含该衍生物的配方，以及制备和使用这些化合物和配方的方法，这些化合物和配方可作为驱虫剂防止昆虫和/或害虫。这些化合物还可以预防因昆虫/害虫传播的疾病和疾病，并提供比现有驱虫剂更安全、更有效的替代品。

  公开号：

  US20120329832A1

文献信息

• LONG-ACTING NANOPARTICULATE ARTHROPOD REPELLENT FORMULATIONS AND METHODS OF USE THEREOF
  申请人：Merial, Inc.

  公开号：EP2871953B1

  公开（公告）日：2018-07-18
• Long-acting nanoencapsulated arthropod repellent formulations and methods of use thereof
  申请人：Delaveau Jean

  公开号：US20140213643A1

  公开（公告）日：2014-07-31

  The present invention relates to novel nanoencapsulated compositions, methods for making such compositions, and methods of repelling insects and other arthropod pests away from animals, including humans. The present invention has particular, though not sole, application to repelling insects including flies and mosquitoes. The inventive compositions may be used to repel arthropods from animals, humans, plants, soil, or building structures. The formulations also prevent illness and disease caused by insect/pest-borne vectors, and provide safer, more effective alternatives to existing repellents.
• US8999362B2
  申请人：——

  公开号：US8999362B2

  公开（公告）日：2015-04-07
• [EN] NOVEL INSECT-REPELLENT COUMARIN DERIVATIVES, SYNTHESES, AND METHODS OF USE<br/>[FR] DÉRIVÉS INSECTIFUGES INÉDITS DE COUMARINE, LEUR SYNTHÈSE ET LEURS PROCÉDÉS D'UTILISATION
  申请人：MERIAL LTD

  公开号：WO2013003168A1

  公开（公告）日：2013-01-03

  This invention relates to novel coumarin derivative, formulations comprising same, and to methods of making and using these compounds and formulations, which are useful as repellents against insects and/or pests. The compounds also prevent illness and disease caused by insect/pest-borne vectors, and provide safer, more effective alternatives to existing repellents.
• [EN] INDIRECT MODELING OF NEW REPELLENT MOLECULES ACTIVE AGAINST INSECTS, ACARIDS, AND OTHER ARTHROPODS<br/>[FR] MODÉLISATION INDIRECTE DE MOLÉCULES RÉPULSIVES INÉDITES ACTIVES CONTRE LES INSECTES, LES ACARIENS ET AUTRES ARTHROPODES
  申请人：MERIAL LTD

  公开号：WO2013044118A2

  公开（公告）日：2013-03-28

  This invention relates to novel coumarin derivatives, formulations comprising same, and to methods of making and using these compounds and formulations, which are useful as repellents against insects and/or pests. The compounds also prevent illness and disease caused by insect/pest-borne vectors, and provide safer, more effective alternatives to existing repellents. This invention also relates to novel methods for modeling and/or predicting the repeilency of unknown compounds.