4-nitro-pyridine-2,6-dicarbonyl dichloride | 73353-49-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-nitro-pyridine-2,6-dicarbonyl dichloride
• 英文别名: 4-nitro-2,6-pyridinedicarbonyl dichloride；4-nitro-2,6-pyridinedicarbonyl chloride；4-Nitropyridine-2,6-dicarbonyl chloride；4-nitropyridine-2,6-dicarbonyl chloride
• CAS: 73353-49-8
• 化学式: C₇H₂Cl₂N₂O₄
• 分子量: 249.01
• InChiKey: UCRNKFPKUBDKGA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  92.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-nitro-pyridine-2,6-dicarbonyl dichloride 在 甲酸 、 三乙胺 作用下， 以 水 为溶剂， 生成 4-nitro-2,6-diacetylpyridine bis(2,4,6-trimethylphenylimine)
  参考文献：
  名称：

  Novel Late Transition Metal Catalysts Based on Iron: Synthesis, Structures and Ethylene Polymerization

  摘要：

  In this article we reported synthesis, characterization and ethylene polymerization behavior of two new late transition metal 2,6-bis(imino)pyridine catalysts based on iron(II) possessing different substituents of NO(2) (catalyst b) and OMe (catalyst c) at the para position of the pyridine ring. Theoretical study exhibited more positive charge on the central metal of the catalyst b, leading to higher activity offset by lower thermal stability and life time.

  DOI：

  10.1007/s10562-010-0433-x
• 作为产物：
  描述：

  2,6-二甲基吡啶 N-氧化物 在 potassium permanganate 、 氯化亚砜 、 硫酸 、 硝酸 、 三苯基膦 作用下， 以 双(2-甲氧基乙基)胺 、 三乙二醇 为溶剂， 反应 8.0h， 生成 4-nitro-pyridine-2,6-dicarbonyl dichloride
  参考文献：
  名称：

  Novel Late Transition Metal Catalysts Based on Iron: Synthesis, Structures and Ethylene Polymerization

  摘要：

  In this article we reported synthesis, characterization and ethylene polymerization behavior of two new late transition metal 2,6-bis(imino)pyridine catalysts based on iron(II) possessing different substituents of NO(2) (catalyst b) and OMe (catalyst c) at the para position of the pyridine ring. Theoretical study exhibited more positive charge on the central metal of the catalyst b, leading to higher activity offset by lower thermal stability and life time.

  DOI：

  10.1007/s10562-010-0433-x

文献信息

• Cation complexing properties of synthetic macrocyclic polyether-diester ligands containing the pyridine subcyclic unit
  作者：J. S. Bradshaw、G. E. Maas、J. D. Lamb、R. M. Izatt、J. J. Christensen

  DOI：10.1021/ja00522a004

  日期：1980.1

  Ten new macrocyclic polyether-diester compounds containing a pyridine subcyclic unit substituted in the 4 position with chloro or methoxy groups have been prepared. These compounds along with their unsubstituted pyridine analogues form strong complexes with alkylammonium and some metal cations. Complexation with alkylammonium and potassium cations was accompanied by significant chemical-shift changes

  已经制备了 10 种新的大环聚醚二酯化合物，其含有在 4 位被氯或甲氧基取代的吡啶亚环单元。这些化合物及其未取代的吡啶类似物与烷基铵和一些金属阳离子形成强配合物。与烷基铵和钾阳离子的络合伴随着 /sup 1/H NMR 光谱中的显着化学位移变化。烷基铵配合物解离的相对活化自由能 (..delta..G/sup 不等于/) 由它们的温度依赖性/sup 1/H NMR 光谱确定。甲氧基取代配体与所有研究的烷基铵离子的配合物具有更大的 ..delta..G/sup 不等于/比氯取代的配体的那些更大。地层常数以及 ..delta..H 和 T..delta.. S 值通过量热技术测定 Na/sup +/、K/sup +/、Rb/sup +/、Ag/sup +/、NH/sub 4//sup +/ 和 Ba/sup 的反应2 +/ 具有包含吡啶和 4-氯吡啶亚环基团的 18 个环成员的配体。碱金属阳离子和这些配体之间形成的配合物几乎与
• LUMINESCENT COMPOUNDS
  申请人：Terpetschnig Ewald A.

  公开号：US20100266507A1

  公开（公告）日：2010-10-21

  Luminescent reporter compounds that are rotaxanes having the structure where B—Z—C is a reporter molecule based on a cyanine, squaric acid, or other reporter, and K is a macrocycle that encircles and interlocks with the reporter molecule. Applications of the reporter compounds are provided, as well as reactive intermediates used to synthesize the reporter compounds, and methods of synthesizing the reporter compounds.

  具有以下结构的轮烷的发光报告化合物，其中B—Z—C是基于青菁、方酸或其他报告物质的报告分子，K是环绕并与报告分子相互锁定的大环。提供了报告化合物的应用，以及用于合成报告化合物的反应中间体和合成报告化合物的方法。
• A pseudorotaxane-based molecular machine controlled by light and thermal stimuli
  作者：Kyu-Sung Jeong、Kyoung-Jin Chang、Young-Jae An

  DOI：10.1039/b303269h

  日期：——

  A new pseudorotaxane-based molecular machine exhibits extremely efficient switching between assembly and disassembly mode, controlled by the combination of light and thermal stimuli.

  一种基于伪紫杉烷的新型分子机器在光和热刺激的共同控制下，在组装和拆卸模式之间实现了极其高效的切换。
• Assembly and Binding Properties of Osmate Ester-Bridged Binuclear Macrocycles
  作者：Kyu-Sung Jeong、Young Lag Cho、Sung-Youn Chang、Tae-Yoon Park、Jung Uk Song

  DOI：10.1021/jo9910841

  日期：1999.12.1

  Osmium (VI)-bridged macrocycles 1a-c, 2, and 3 assemble spontaneously when osmium tetraoxide, olefins, and L-shaped bispyridyl ligands are mixed in CHCl3. The macrocycles possess well-defined square or rectangular cavities enclosed by aryl walls and act as host molecules. Hydrogen-bond donors on the inner surface of the hosts offer binding sites to accepters of guests with complementary dimensions. The host la binds adipamide G2 (K-a = 3.6 x 10(4) M-1) and terephthalamide G6 (K-a = 2.0 x 10(4) M-1), while it binds negligibly (K-a < 10 M-1) benzamide G5, isophthalamide G9, or 1,4-naphthalenedicarboxamide G10. The larger hosts 2 and 3 bind the longer guests biphenyldicarboxamide G12 and terphenyldicarboxamide G17, respectively, but shorter guests such as adipamide G2 and terephthalamide G6 are not well-bound (K-a < 10 M-1). Hosts 1a-e with different remote substituents (H, OMe, NO2) but identical cavity size were prepared and their binding affinities were measured. The relative binding affinities of the hosts 1a-c to the keto amide G19, ester amide G20, and diester G21 are in the order of 1c (NO2) much greater than 1a (H) > 1b (OCH3). The substituent effects on the binding strength are interpreted in terms of the electron density at the pyridine nitrogen of the hosts and its effect on bifurcated hydrogen bonding.
• Efficient Modulation of Hydrogen-Bonding Interactions by Remote Substituents
  作者：Sung-Youn Chang、Hung Sop Kim、Kyoung-Jin Chang、Kyu-Sung Jeong

  DOI：10.1021/ol035954j

  日期：2004.1.1

  [GRAPHICS]A series of tetralactam macrocycles having different substituents were prepared, and their binding affinities for an adipamide guest were investigated in CDCl(3) by (1)H NMR titrations. The association constants strongly depend on the substituents, varying up to DeltaDeltaG = 3.4 kcal/mol; electron-donating substituents (OMe, NMe(2)) decrease the binding affinity, while electron-withdrawing groups (Cl, NO(2)) increase it. These large substituent effects have been rationalized by secondary repulsions and partial perturbations of intramolecular hydrogen bonds.