7-decynoic acid | 54373-85-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7-decynoic acid
• 英文别名: 7-Decinsaeure；dec-7-ynoic acid
• CAS: 54373-85-2
• 化学式: C₁₀H₁₆O₂
• 分子量: 168.236
• InChiKey: CGCUYMJELYAFRU-UHFFFAOYSA-N

物化性质

• 熔点：
  28.5°C (estimate)
• 沸点：
  325.33°C (rough estimate)
• 密度：
  1.0066 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  7-decynoic acid 在 PdCl2(PPh3)2 三氟化硼 、 氘 作用下， 20.0 ℃ 、101.33 kPa 条件下， 生成 Methyl (7,7,8,8)D4-decanoate
  参考文献：
  名称：

  Why not be a queen? Regioselectivity in mandibular secretions of honeybee castes

  摘要：

  Both female castes of the honeybee (Apis mellifera L.) synthesize hydroxylated 2(E)-decenoic acids in their mandibular glands. Queens produce 9-hydroxy-2(E)-decenoic acid as part of their primer pheromone, while workers produce the regioisomeric 10-hydroxy acid, probably as a larval food source and an antiseptic secretion. Both workers and queens are biosynthetically competent to produce the other caste's dominant hydroxylated compound, as both isomers can be detected in queens and workers. We investigated the source of the caste-determined regioselectivity of hydroxy acid biosynthesis by investigating the production and interconversion of these compounds in isolated worker honeybee mandibular glands with specifically deuterated precursors. Gas chromatographic-mass spectroscopic identification of the labeled product indicates that octadecanoic acid is converted into 10-hydroxy-2(E)-decenoic acid with higher efficiency than either hexadecanoic or decanoic acids. 10-Hydroxydecanoic acid is readily converted into 10-hydroxy-2(E)-decenoic acid as expected in the beta-oxidation process. The saturated and unsaturated 10-hydroxy acids are oxidized to the corresponding ten carbon diacids.

  DOI：

  10.1007/bf02033805
• 作为产物：
  描述：

  7-Decynoic acid methyl ester 在 氢氧化钾 作用下， 以 甲醇 为溶剂， 反应 24.0h， 生成 7-decynoic acid
  参考文献：
  名称：

  Seidel, Wolfgang; Schaefer, Hans J., Chemische Berichte, 1980, vol. 113, # 12, p. 3898 - 3903

  摘要：

  DOI：

文献信息

• Production of substituted acetylenic compounds
  申请人：Takeda Chemical Industries, Ltd.

  公开号：US04871868A1

  公开（公告）日：1989-10-03

  A method of producing substituted acetylenic compounds which comprises: reacting an organic compound having the general formula of A--X (I) wherein A represents a saturated or unsaturated aliphatic hydrocarbon residue of 1-20 carbon atoms which may have one or more substituents inactive in the reaction, and X represents a halogen atom or an arylsulfonyloxy group, with a metal acetylide having the general formula of M--C.tbd.C--B (II) wherein M represents an alkali metal, and B represents (a) a hydrogen, (b) a saturated or unsaturated hydrocarbon residue which may have one or more substituents inactive in the reaction, or (c) a saturated or unsaturated hydrocarbon residue which has a substituent having the general formula of --C.tbd.C--M (III) wherein M represents an alkali metal, in the presence of an alkyl-2-imidazolidinone having the general formula of ##STR1## wherein R.sup.1 and R.sup.2 independently represent a lower alkyl, and R.sup.3 represents a hydrogen or a lower alkyl.

  一种生产取代乙炔化合物的方法，包括：将具有通式A--X（I）的有机化合物与具有通式M--C≡C--B（II）的金属乙炔炔基反应，在2-咪唑烷酮存在下进行。其中，A代表1-20个碳原子的饱和或不饱和脂肪烃基，可能有一个或多个在反应中不活性的取代基；X代表卤素原子或芳基磺酰氧基团；M代表碱金属；B代表（a）氢、（b）可能有一个或多个在反应中不活性的饱和或不饱和碳氢基，或（c）具有通式--C≡C--M（III）的取代基团，其中M代表碱金属；2-咪唑烷酮具有通式##STR1## 其中R.sup.1和R.sup.2独立表示较低的烷基，R.sup.3表示氢或较低的烷基。
• The intramolecular 1,3-dipolar cyclisation of mesoionic species generated by the thermolysis of the mixed anhydrides of acetic and N-alkynoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
  作者：Malcolm Sainsbury、Rosalind H. Strange、Peter R. Woodward、Paul A. Barsanti

  DOI：10.1016/s0040-4020(01)86306-7

  日期：1993.3

  The intramolecular cyclisations of mesoionic intermediates formed by heating N-alkynoyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids [alkylnoyl side chains: RCC-(CH2)2CO, where n = 3 or 4] with acetic anhydride, have been investigated. The final products are octahydropentaleno[2,3-a]isoquinolines and hexahydroindeno[2,3-a]isoquinolines respectively, formed by the expulsion of carbon dioxide from

  通过加热N-炔基-1,2,3,4-四氢异喹啉-3-羧酸[烷酰基侧链：RCC-（CH 2）2 CO，其中n = 3或4]形成的介电中间体的分子内环化用乙酸酐进行研究。最终产品是octahydropentaleno [2,3-一个]异喹啉和hexahydroindeno [2,3-一个]异喹啉分别由二氧化碳的从最初的加合物驱逐形成。还研究了分子间形式的环加成反应中烯烃和炔烃作为亲二烯体的行为。带有吸电子基团的炔烃提供吡咯并[1,2- b异喹啉，但除非使用烯烃，如亚苄基亚甲基苯二腈（首先形成的加合物可在失去CO 2之前消除HCN），否则反应将失败。
• TAKASIMA, SEHJSUKEH
  作者：TAKASIMA, SEHJSUKEH

  DOI：——

  日期：——
• SAITO, YUZURU;YOSHIDA, KOKICHI
  作者：SAITO, YUZURU、YOSHIDA, KOKICHI

  DOI：——

  日期：——
• US4871868A
  申请人：——

  公开号：US4871868A

  公开（公告）日：1989-10-03