2-(3,5-dibromo-2-hydroxybenzoylamino)benzimidazole | 81268-66-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(3,5-dibromo-2-hydroxybenzoylamino)benzimidazole
• 英文别名: N-(1H-benzimidazol-2-yl)-3,5-dibromo-2-hydroxybenzamide
• CAS: 81268-66-8
• 化学式: C₁₄H₉Br₂N₃O₂
• 分子量: 411.052
• InChiKey: RJYICZQJKGSPBU-UHFFFAOYSA-N

物化性质

• 熔点：
  317-318 °C(Solv: acetic acid (64-19-7))
• 密度：
  2.007±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  78
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3,5-二溴-2-羟基苯甲酸 在 N,N-二甲基甲酰胺 氯化亚砜 、 三乙胺 作用下， 以 氯仿 、 丙酮 为溶剂， 生成 2-(3,5-dibromo-2-hydroxybenzoylamino)benzimidazole
  参考文献：
  名称：

  Acyl Derivatives of 2-Aminobenzimidazole and Their Fungicide Activity

  摘要：

  Procedures have been developed for the preparation of methyl 2-benzimidazolylcarbamate, 2-acetylaminobenzimidazole, 2-benzoylaminobenzimidazole, 2-(3,5-dibromo-2-hydroxybenzoylamino)benzimidazole, 1-(3,6-dichloro-2-methoxybenzoyl)-2-aminobenzimidazole, 2-(3,5-dichloro-2-hydroxybenzoylamino)benzimidazole, 2-(3,5-dichloro-2-methoxybenzoylamino)benzimidazole, and 1-(3,5,6-trichloro-2-methoxybenzoyl)-2-aminobenzimidazole. The synthesized compounds have been tested for fungicide activity.

  DOI：

  10.1023/b:rugc.0000039088.87053.eb

文献信息

• Sluka, Jaroslav; Danek, Jaroslav; Bedrnik, Petr, Collection of Czechoslovak Chemical Communications, 1981, vol. 46, # 11, p. 2703 - 2708
  作者：Sluka, Jaroslav、Danek, Jaroslav、Bedrnik, Petr、Budesinsky, Zdenek

  DOI：——

  日期：——
• 13C NMR spectra and biological activity of N-(1H-benzimidazol-2-yl)benzamides
  作者：V. S. Pilyugin、Yu. E. Sapozhnikov、A. M. Davydov、G. E. Chikisheva、T. P. Vorob’eva、E. V. Klimakova、G. V. Kiseleva、S. L. Kuznetsova、R. D. Davletov、N. A. Sapozhnikova、R. Kh. Yumadilov

  DOI：10.1134/s1070363206100264

  日期：2006.10

  Derivatives of 1H-benzimidazol-2-amine and halo-, nitro-, methoxy-, and hydroxy-substituted benzoic acids were synthesized, and their fungicide activity against pure Fusarium culmorum and Helminthosporium sativum cultures and pathogenic microflora of wheat and barley seeds in laboratory and field tests was studied. Some compounds were found to exhibit a strong fungicide activity.
• SLUKA, J.;DANEK, J.;BEDRNIK, P.;BUDESINSKY, Z., COLLECT. CZECH. CHEM. COMMUN., 1981, 46, N 11, 2703-2708
  作者：SLUKA, J.、DANEK, J.、BEDRNIK, P.、BUDESINSKY, Z.

  DOI：——

  日期：——