(Z)-(3-fluoro-2-methyl-3-phenylprop-2-ene-1,1-diyl)dibenzene | 1616471-10-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (Z)-(3-fluoro-2-methyl-3-phenylprop-2-ene-1,1-diyl)dibenzene
• 英文别名: [(E)-1-fluoro-2-methyl-3,3-diphenylprop-1-enyl]benzene
• CAS: 1616471-10-3
• 化学式: C₂₂H₁₉F
• 分子量: 302.391
• InChiKey: SOHGQCNAYSTUPB-OQKWZONESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  二苯甲醇 、 1-苯基-1-丁炔 在 tetrafluoroboric acid 作用下， 以 1,2-二溴乙烷 为溶剂， 以24%的产率得到
  参考文献：
  名称：

  Simple and convenient synthesis of fluoroalkenes via direct coupling of alcohols, alkynes and fluoroboric acid under metal-free conditions

  摘要：

  A novel and convenient method for the synthesis of fluoroalkenes from alkynes, alcohols and fluoroboric acid has been developed under mild conditions. The present protocol provides an attractive approach to access various fluoroalkenes from simple and commercially available starting materials without any metal catalyst, ligand or additive. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.069

文献信息

• Simple and convenient synthesis of fluoroalkenes via direct coupling of alcohols, alkynes and fluoroboric acid under metal-free conditions
  作者：Xiao-wei Yan、Qiang Zhang、Wei Wei、Jian-xin Ji

  DOI：10.1016/j.tetlet.2014.05.069

  日期：2014.7

  A novel and convenient method for the synthesis of fluoroalkenes from alkynes, alcohols and fluoroboric acid has been developed under mild conditions. The present protocol provides an attractive approach to access various fluoroalkenes from simple and commercially available starting materials without any metal catalyst, ligand or additive. (C) 2014 Elsevier Ltd. All rights reserved.