tert-butyl-(7-(4-methoxyphenyl)octyloxy)diphenylsilane | 1201553-55-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: tert-butyl-(7-(4-methoxyphenyl)octyloxy)diphenylsilane
• 英文别名: Tert-butyl-[7-(4-methoxyphenyl)octoxy]-diphenylsilane
• CAS: 1201553-55-0
• 化学式: C₃₁H₄₂O₂Si
• 分子量: 474.759
• InChiKey: BDXULPULBSVUQI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.33
• 重原子数：
  34
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-甲氧基苯乙烯 、 OTBDPShexylZnBr 在 Pd(IiPr)(OTs)2 、 zinc trifluoromethanesulfonate 、 对苯醌 作用下， 以 N,N-二甲基乙酰胺 为溶剂， 反应 1.5h， 以85%的产率得到tert-butyl-(7-(4-methoxyphenyl)octyloxy)diphenylsilane
  参考文献：
  名称：

  Palladium-Catalyzed Hydroalkylation of Styrenes with Organozinc Reagents To Form Carbon−Carbon sp³−sp³ Bonds under Oxidative Conditions

  摘要：

  An unconventional route for the formation of sp(3)-sp(3) C-C bonds from various styrenes and an organozinc reagent in a formal alkene hydroalkylation process is detailed. Mechanistically, this process is proposed to proceed by initial transmetalation followed by formation of a Pd-H species, which is subsequently trapped by the styrene.

  DOI：

  10.1021/ja908545b

文献信息

• Palladium-Catalyzed Hydroalkylation of Styrenes with Organozinc Reagents To Form Carbon−Carbon sp³−sp³ Bonds under Oxidative Conditions
  作者：Kaveri Balan Urkalan、Matthew S. Sigman

  DOI：10.1021/ja908545b

  日期：2009.12.23

  An unconventional route for the formation of sp(3)-sp(3) C-C bonds from various styrenes and an organozinc reagent in a formal alkene hydroalkylation process is detailed. Mechanistically, this process is proposed to proceed by initial transmetalation followed by formation of a Pd-H species, which is subsequently trapped by the styrene.