triethoxysilyltriflate | 120541-70-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: triethoxysilyltriflate
• 英文别名: Triethoxysilyl trifluoromethanesulfonate
• CAS: 120541-70-0
• 化学式: C₇H₁₅F₃O₆SSi
• 分子量: 312.339
• InChiKey: RXWBNPYLWRHOHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.4
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  苯甲醚 、 triethoxysilyltriflate 在 正丁基锂 、 四甲基乙二胺 作用下， 以 乙醚 、 正己烷 、 四氢呋喃 为溶剂， 反应 3.0h， 以88%的产率得到(2-甲氧基苯基)三乙氧基硅烷
  参考文献：
  名称：

  Application of Directed Orthometalation toward the Synthesis of Aryl Siloxanes

  摘要：

  A selection of ortho-substituted aryl siloxanes have been prepared by directed orthometalation protocols. These siloxanes can be prepared in high yields and purity by use of a diverse selection of ortho-directing groups and electrophilic siloxane derivatives. The siloxanes are employed in palladium-catalyzed cross-coupling reactions with aryl bromides to generate unsymmetrical orthosubstituted biaryls in good to excellent yields.

  DOI：

  10.1021/jo0492057
• 作为产物：
  描述：

  烯丙基三乙氧基硅烷 、 三氟甲磺酸 以 二氯甲烷 为溶剂， 反应 2.0h， 生成 triethoxysilyltriflate
  参考文献：
  名称：

  Application of Directed Orthometalation toward the Synthesis of Aryl Siloxanes

  摘要：

  A selection of ortho-substituted aryl siloxanes have been prepared by directed orthometalation protocols. These siloxanes can be prepared in high yields and purity by use of a diverse selection of ortho-directing groups and electrophilic siloxane derivatives. The siloxanes are employed in palladium-catalyzed cross-coupling reactions with aryl bromides to generate unsymmetrical orthosubstituted biaryls in good to excellent yields.

  DOI：

  10.1021/jo0492057

文献信息

• Application of Directed Orthometalation toward the Synthesis of Aryl Siloxanes
  作者：W. Michael Seganish、Philip DeShong

  DOI：10.1021/jo0492057

  日期：2004.10.1

  A selection of ortho-substituted aryl siloxanes have been prepared by directed orthometalation protocols. These siloxanes can be prepared in high yields and purity by use of a diverse selection of ortho-directing groups and electrophilic siloxane derivatives. The siloxanes are employed in palladium-catalyzed cross-coupling reactions with aryl bromides to generate unsymmetrical orthosubstituted biaryls in good to excellent yields.