(R)-N-benzylleucine | 89384-51-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (R)-N-benzylleucine
• 英文别名: (2R)-2-(benzylazaniumyl)-4-methylpentanoate
• CAS: 89384-51-0
• 化学式: C₁₃H₁₉NO₂
• 分子量: 221.299
• InChiKey: ZJOWTIPPMQBTTA-GFCCVEGCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

反应信息

• 作为反应物：
  描述：

  (R)-N-benzylleucine 在 palladium on activated charcoal 氢气 作用下， 以 溶剂黄146 为溶剂， 反应 24.0h， 以98%的产率得到D-亮氨酸
  参考文献：
  名称：

  Hassan, Nasser A.; Bayer, Erwin; Jochims, Johannes C., Journal of the Chemical Society. Perkin transactions I, 1998, # 22, p. 3747 - 3757

  摘要：

  DOI：
• 作为产物：
  描述：

  (R)-N-Benzylleucinamide 在 盐酸 、 水 作用下， 反应 4.0h， 以94%的产率得到(R)-N-benzylleucine
  参考文献：
  名称：

  Hassan, Nasser A.; Bayer, Erwin; Jochims, Johannes C., Journal of the Chemical Society. Perkin transactions I, 1998, # 22, p. 3747 - 3757

  摘要：

  DOI：

文献信息

• Methods for modulating taste receptors
  申请人：MARS, INCORPORATED

  公开号：US11185100B2

  公开（公告）日：2021-11-30

  Amino acids present in domains of an umami taste receptor are described herein, wherein the amino acids interact with at least one nucleotide derivative and/or at least one transmembrane compound that potentiates, modulates, increases, and/or enhances the activity of the umami receptor. Such compounds can be used in flavor compositions to enhance the umami taste and/or palatability of food products.

  本文描述了存在于鲜味受体结构域中的氨基酸，其中氨基酸与至少一种核苷酸衍生物和/或至少一种跨膜化合物相互作用，从而增强、调节、增加和/或提高鲜味受体的活性。此类化合物可用于调味组合物，以增强食品的鲜味和/或适口性。
• A Practical Approach to the Resolution of RacemicN-Benzyl α-Amino Acids by Liquid–Liquid Extraction with a Lipophilic Chiral Salen–Cobalt(III) Complex
  作者：Toby B. Reeve、Jean-Philippe Cros、Cesare Gennari、Umberto Piarulli、Johannes G. de Vries

  DOI：10.1002/anie.200504116

  日期：2006.4.3
• Kadyrov, Renat; Riermeier, Thomas H.; Dingerdissen, Uwe, Journal of Organic Chemistry, 2003, vol. 68, # 10, p. 4067 - 4070
  作者：Kadyrov, Renat、Riermeier, Thomas H.、Dingerdissen, Uwe、Tararov, Vitali、Boerner, Armin

  DOI：——

  日期：——
• FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME
  申请人：MARS, INCORPORATED

  公开号：US20180168208A1

  公开（公告）日：2018-06-21

  A flavor composition comprising at least one nucleotide derivative and/or at least one transmembrane compound that modulates, increases and/or enhances the activity of an umami receptor is provided that can be used to enhance the umami taste and/or palatability of food products. In certain, non-limiting embodiments, the flavor composition comprises at least one nucleotide derivative and/or at least one transmembrane compound, optionally at least one nucleotide, optionally at least one first amino acid, optionally at least one second amino acid.
• [EN] FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME<br/>[FR] COMPOSITIONS AROMATISANTES ET PRODUITS ALIMENTAIRES POUR ANIMAUX DE COMPAGNIE LES CONTENANT
  申请人：MARS INC

  公开号：WO2016094690A1

  公开（公告）日：2016-06-16

  A flavor composition comprising at least one nucleotide derivative and/or at least one transmembrane compound that modulates, increases and/or enhances the activity of an umami receptor is provided that can be used to enhance the umami taste and/or palatability of food products. In certain, non-limiting embodiments, the flavor composition comprises at least one nucleotide derivative and/or at least one transmembrane compound, optionally at least one nucleotide, optionally at least one first amino acid, optionally at least one second amino acid.