1,2,3,4-Tetrahydro-[2]anthrol | 58800-49-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1,2,3,4-Tetrahydro-[2]anthrol
• 英文别名: ac. Tetrahydro-β-anthrol；2-Oxy-1.2.3.4-tetrahydro-anthracen；Anthracene, 1,2,3,4-tetrahydro-2-ol；1,2,3,4-tetrahydroanthracen-2-ol
• CAS: 58800-49-0
• 化学式: C₁₄H₁₄O
• 分子量: 198.265
• InChiKey: FCXKPBDLSOIBTN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,2,3,4-Tetrahydro-[2]anthrol 在 镍 、 萘烷 作用下， 生成 对称八氢蒽
  参考文献：
  名称：

  v. Braun; Bayer, Justus Liebigs Annalen der Chemie, 1929, vol. 472, p. 104

  摘要：

  DOI：
• 作为产物：
  描述：

  2,10-Dihydroxyanthracene 在 异戊醇 、 sodium 、 镍 作用下， 生成 1,2,3,4-Tetrahydro-[2]anthrol
  参考文献：
  名称：

  v. Braun; Bayer, Justus Liebigs Annalen der Chemie, 1929, vol. 472, p. 104

  摘要：

  DOI：

文献信息

• Enantioselectivity in the reduction of tricyclic hydroaromatic ketones by baker's yeast
  作者：Gabriele Fontana、Paolo Manitto、Giovanna Speranza、Simona Zanzola

  DOI：10.1016/s0957-4166(98)00111-6

  日期：1998.4

  Three benzo-2-tetralones were hydrogenated to the corresponding alcohols by non-fermenting baker's yeast. Satisfactory yields but modest enantioselectivities were observed. The prevalent enantioform of the benzo-2-tetralol was found to be in agreement with the predictive abstract model previously proposed for the enzymatic hydrogenation of aromatic ring substituted 2-tetralones.

  通过非发酵面包酵母将三种苯并-2-四氢萘酮氢化为相应的醇。令人满意的产率，但是观察到适度的对映选择性。发现苯并-2-戊醇的普遍对映体与先前提出的用于芳香环取代的2-四氢萘酮的酶促氢化的预测抽象模型相符。
• Arene 1,4-Diradical Formation from o-Dialkynylarenes
  作者：M. F. Semmelhack、Thomas Neu、Francisco Foubelo

  DOI：10.1021/jo00096a057

  日期：1994.8

  A series of 10-membered cyclic 1,5-diynes has been prepared with arene rings fused at positions C-3/C-4. The arenes include simple benzene rings, a naphthoquinone and naphthohydroquinone, and an anthraquinone and anthracene unit. Consistent with a simple picture relating the extent of double bond character in the ene part of the ene-diyne with the rate of arene-l,l-diyl formation, the hydroquinone derivatives were much less reactive compared to the corresponding quinones. Substituents such as propargylic hydroxyl or keto group have a small but significant activating effect. The parent 3,4-benzo-1,8-decadiyne shows a half-life for rearrangement of 24 h at 84 degrees C while the corresponding alkene, cyclodec-3-ene-1,5-diyne is reported to have a half-life of 18 h at 37 degrees C.
• Cook et al., Journal of the Chemical Society, 1950, p. 911,914
  作者：Cook et al.

  DOI：——

  日期：——
• AKHTAR M. N.; BOYD D. R.; HAMILTON J. G., J. CHEM. SOC. PERKIN TRANS., 1979, PART 1, NO 10, 2437-2440
  作者：AKHTAR M. N.、 BOYD D. R.、 HAMILTON J. G.

  DOI：——

  日期：——