1H-benzimidazole; copper (II)-salt | 3087-53-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 1H-benzimidazole; copper (II)-salt
• 英文别名: [Cu(benzimidazolate)2]；[Cu(bzd)2]；1H-Benzimidazol; Kupfer(II)-Salz；copper benzimidazolate
• CAS: 3087-53-4；124528-47-8
• 化学式: 2C₇H₅N₂*Cu
• 分子量: 297.806
• InChiKey: CECDGXYDLVORSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.19
• 重原子数：
  10.0
• 可旋转键数：
  0.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  26.99
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  Cu(benzoate)2(benzimidazole)2 以 二甲基亚砜 为溶剂， 生成 1H-benzimidazole; copper (II)-salt
  参考文献：
  名称：

  Synthesis, catalase, superoxide dismutase and antitumour activities of copper(II) carboxylate complexes incorporating benzimidazole, 1,10-phenanthroline and bipyridine ligands: X-ray crystal structures of [Cu(BZA)2(bipy)(H2O)], [Cu(SalH)2(BZDH)2] and [Cu(CH3COO)2(5,6-DMBZDH)2] (SalH2=salicylic acid; BZAH=benzoic acid; BZDH=benzimidazole and 5,6-DMBZDH=5,6-dimethylbenzimidazole)

  摘要：

  A series of simple Cu(II) carboxylate complexes {carboxylate = acetate (CH3COO), salicylate (salH) or benzoate (BZA)}, some containing either one chelating {1,10-phenanthroline (phen) or 2,2 '-bipyridine (bipy)} or two monodentate {benzimidazole (BZDH) or 5,6-dimethylbenzimidazole (5,6-DMBZDH)) nitrogen donor ligands, have been prepared and characterised. X-ray crystal structures have been determined for the square pyramidal complex [Cu(BZA)(2)(bipy)(H2O)] and the two square planar complexes [Cu(CH3COO)(2) (5,6-DMBZDH)(2)] and [Cu(salH)(2)(BZDH)(2)]. All of the complexes are poor catalase mimics in the presence of imidazole and totally inactive in its absence. The complexes all exhibit excellent superoxide dismutase (SOD) mimetic activity and the two phen derivatives [Cu(CH3COO)(2)(phen)] and [Cu(sal)(phen)] display potent in vitro cytotoxicity against human hepatic (Hep-G), renal (A-498) and lung (A-549) cancer cell lines. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2007.05.006

文献信息

• A web of poly(bisbenzimidazolatocopper(<scp>ii</scp>)) around multiwalled carbon nanotubes for the electrochemical detection of hydrogen peroxide
  作者：Tamilselvi Gurusamy、Rajendran Rajaram、Raja Murugan、Kothandaraman Ramanujam

  DOI：10.1039/d1nj04903h

  日期：——

  work focuses on the electrochemical determination of hydrogen peroxide (H2O2), using poly(bisbenzimidazolatocopper(II)) coordinated multiwalled carbon nanotube modified glassy carbon electrode (MWCNT/(BIM–Cu2+)n@GCE). The physical characterization techniques point to the coordination of the polymer web around MWCNT. The electrode matrix developed was employed for the electrochemical estimation of H2O2

  目前的工作重点是使用聚（双苯并咪唑基铜（II））配位的多壁碳纳米管修饰的玻碳电极（MWCNT/（BIM–Cu 2+）n @GCE）电化学测定过氧化氢（H 2 O 2）。物理表征技术指向聚合物网在 MWCNT 周围的协调。开发的电极矩阵用于 H 2 O 2的电化学估计。该聚合物在 MWCNT 存在下效果更好，因为它充当导电辐条，这对于 H 2 O 2的成功电化学传感具有重要意义. 据我们所知，这种用于感应过氧化物的配位聚合物网是首次报道。在电流检测中，电极表现出7.8 × 10 -7 M的 H 2 O 2检测限和 5 nA μM -1的灵敏度。通过干扰研究进一步证明了电极的有效性，并将其应用于实际样品中的H 2 O 2传感。
• High metal loaded Cu(<scp>i</scp>)N₃ single-atom catalysts: superior methane conversion activity and selectivity under mild conditions
  作者：Hyesung Lee、Sang-Yup Lee

  DOI：10.1039/d3ta02450d

  日期：——

  which outperforms the previously reported thermocatalysts including not only non-noble metals (Cu and Fe), but also noble metals (AuPd and Rh), with a comparable selectivity of ∼90% toward C1 liquid products. This considerable methane conversion activity was achieved by combining both high metal loading and the under-coordinated Cu active site. The experimental studies revealed that the superoxide radical

  将甲烷直接转化为甲醇等液化产品是天然气资源在储存和运输过程中有效利用的重要过程。然而，由于 C-H 键的高能垒，这一过程仍然是一个挑战。为了解决这个问题，我们开发了一种氮掺杂碳催化剂（CuNC-600），含有欠配位单原子Cu( I )N 3活性中心，具有高达17.7 wt%的超高金属负载量。我们的研究报告使用 H 2 O 2在 50 °C 时的质量活性为 6.1 mmol g −1作为氧化剂，其性能优于之前报道的热催化剂，不仅包括非贵金属（Cu和Fe），还包括贵金属（AuPd和Rh），对C1液体产物具有约90%的选择性。这种相当大的甲烷转化活性是通过结合高金属负载量和欠配位的铜活性位点来实现的。实验研究表明，超氧自由基控制CH 3 OH和CH 3 OOH生成的整个反应途径，而羟基自由基主要参与甲烷活化。
• WO2007/87434
  申请人：——

  公开号：——

  公开（公告）日：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Cu: MVol.B4, 121, page 1709 - 1711
  作者：

  DOI：——

  日期：——
• Ghosh, S. P., Journal of the Indian Chemical Society, 1951, vol. 28, p. 710 - 712
  作者：Ghosh, S. P.

  DOI：——

  日期：——