hexylglyoxal monohydrate | 151587-63-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: hexylglyoxal monohydrate
• 英文别名: 1,1-Dihydroxy-2-octanone；1,1-dihydroxyoctan-2-one
• CAS: 151587-63-2
• 化学式: C₈H₁₆O₃
• 分子量: 160.213
• InChiKey: DJPWBJDZNFZWAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-氧-4-(三苯基膦)丁酸乙酯 、 hexylglyoxal monohydrate 以 乙醇 为溶剂， 反应 24.0h， 以53%的产率得到
  参考文献：
  名称：

  A single-step synthesis of 4-hydroxycyclopentenones from 3-Ethoxycarbonyl-2-oxo-propylidenetriphenylphosphorane and glyoxals

  摘要：

  3-Ethoxycarbonyl-2-oxo-propylidenetriphenylphosphorane undergoes a [3+2]-annulation reaction with a variety of glyoxals to give 4-hydroxycyclopentenones in good to moderate yields.

  DOI：

  10.1016/s0040-4039(00)74103-7
• 作为产物：
  描述：

  仲辛酮 在 selenium(IV) oxide 、 水 作用下， 以 1,4-二氧六环 为溶剂， 生成 hexylglyoxal monohydrate
  参考文献：
  名称：

  TOX/Cu(II)催化下的高效和对映选择性分子内坎尼扎罗反应

  摘要：

  基于新开发的拥挤 TOX 配体和活性乙二醛从乙二醛一水合物中逐渐释放的方案，芳基和烷基乙二醛与醇的不对称分子内 Cannizzaro 反应以前所未有的高水平对映选择性实现。初步结果表明，除了半缩醛中间体的动态动力学拆分之外，醇对映选择性加成到乙二醛的机制对立体选择性贡献最大。

  DOI：

  10.1021/ja409859x

文献信息

• Cyclopent-2-en-1-ones from [3+2]-annulation of 3-ethoxycarbonyl-2-propenylidene(triphenyl)-phosphorane and glyoxals: Synthesis of cis-jasmone
  作者：Md.Saiful Islam、Tomikazu Kawano、Minoru Hatanaka、Ikuo Ueda

  DOI：10.1016/0040-4039(96)01213-0

  日期：1996.8

  [3+2]-annulation reaction in the presence of a base. Compounds 6 were easily converted to 2-substituted cyclopent-2-en-1-ones by deethoxycarbonylation. An application of the annulation to synthesis of cis-jasmone is also described.

  3-乙氧基羰基-2-丙烯（三苯基）亚膦酸酯（2）与乙二醛一水合物（5）反应，在[3 + 2]-环化反应中，生成2-取代的5-乙氧基羰基环戊-2-烯-1-酮（6）。基地的存在。化合物6通过脱乙氧基羰基化容易地转化为2-取代的环戊-2-烯-1-酮。还描述了该成环法在顺式-茉莉酮合成中的应用。
• PROTEIN EXHIBITING FATTY ACID ELONGATION PROMOTING ACTIVITY, GENE ENCODING SAME AND USE THEREOF
  申请人：Suntory Holdings Limited

  公开号：EP2740797A1

  公开（公告）日：2014-06-11

  The present invention relates to a protein having an activity to promote fatty acid chain elongation, a polynucleotide encoding the same, etc. The present invention provides, for example, a polynucleotide containing the nucleotide sequence shown in SEQ ID NO: 1 or 4, a polynucleotide encoding a protein which consists of the amino acid sequence shown in SEQ ID NO: 2, an expression vector and a transformant, each containing such a polynucleotide, a method for preparing lipids or fatty acids by using such a transformant, or a food or the like containing lipids or fatty acids prepared by such a method.

  本发明涉及一种具有促进脂肪酸链延长活性的蛋白质、编码该蛋白质的多核苷酸等。例如，本发明提供了一种含有 SEQ ID NO: 1 或 4 所示核苷酸序列的多核苷酸、一种编码由 SEQ ID NO: 2 所示氨基酸序列组成的蛋白质的多核苷酸、一种表达载体和一种转化体（每种载体都含有这种多核苷酸）、一种使用这种转化体制备脂质或脂肪酸的方法，或一种含有用这种方法制备的脂质或脂肪酸的食品或类似物。
• METHOD FOR IDENTIFYING USEFUL PROTEINS OF BREWERY YEAST
  申请人：Suntory Limited

  公开号：EP1994150A1

  公开（公告）日：2008-11-26
• Method for identifying useful proteins of brewery yeast
  申请人：Suntory Holdings Limited

  公开号：EP2275542B1

  公开（公告）日：2012-12-12
• Method for Identifying Useful Proteins of Brewery Yeast
  申请人：Nakao Yoshihiro

  公开号：US20090311680A1

  公开（公告）日：2009-12-17

  The invention relates to a method for identifying a useful protein of brewery yeast. More specifically, the invention relates to (a) cultivating yeast under a predetermined cultivation condition; (b) extracting a protein sample from the cultivation product of the yeast; (c) separating the protein sample by a protein separation means, selecting a target peak or spot, and recovering the target protein or a fragment thereof contained in the peak or spot; (d) determining the amino acid sequence of the target protein; (e) comparing the amino acid sequence determined in step (d) with the amino acid sequence determined in advance based on all or a part of genome sequence information of bottom fermenting yeast; (f) identifying the target protein and the gene encoding the target protein based on the results of comparison; and (g) analyzing functions of the identified gene to identify characters given to the yeast by the gene.