1,2:3,4-di-O-sulfinyl erythritol | 92175-74-1

• 分子结构分类: 有机化合物 - 有机氧化合物 - 有机含氧阴离子化合物
• 英文名称: 1,2:3,4-di-O-sulfinyl erythritol
• 英文别名: di-O-sulfinyl-meso-erythritol；disulfite of natural erythritol；Disulfit des natuerlichen Erythrits；(4S)-4-[(4R)-2-oxo-1,3,2-dioxathiolan-4-yl]-1,3,2-dioxathiolane 2-oxide
• CAS: 92175-74-1
• 化学式: C₄H₆O₆S₂
• 分子量: 214.22
• InChiKey: FIMJFTMDXIQQBE-OKVYMDCHSA-N

物化性质

• 熔点：
  50-53 °C
• 沸点：
  372.8±42.0 °C(Predicted)
• 密度：
  2.03±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  110
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1,2:3,4-di-O-sulfinyl erythritol 在 sodium azide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 1.0h， 以80%的产率得到1,4-diazido-1,4-dideoxyerythritol
  参考文献：
  名称：

  Synthesis of α,ω‐Diazidoalditol Derivatives via Both bis‐ or tris‐Cyclic Sulfites and Peracetylated α,ω‐Dibromoalditols as Bielectrophilic Intermediates

  摘要：

  The alpha,omega-diazidoalditol derivatives with erythro, threo, xylo, ribo, D-arabino, D-manno, and D-gluco configuration were efficiently synthesized, respectively, from bis- or tris-cyclic sulfite or peracetylated alpha,omega-dibromoalditol intermediates. The cyclic sulfite intermediates has the advantage to lead directly to the free alpha,omega-diazido-alpha,omega-dideoxyalditols.

  DOI：

  10.1081/car-120030470
• 作为产物：
  描述：

  Erythritol 在 吡啶 、 氯化亚砜 作用下， 以 二氯甲烷 为溶剂， 反应 0.67h， 生成 1,2:3,4-di-O-sulfinyl erythritol
  参考文献：
  名称：

  通过未保护的醇直接叠氮化制备α，ω-二氨基醇的新有效方法

  摘要：

  通过用亚硫酰氯和叠氮化钠相继处理，将未保护的戊糖醇和赤藓糖醇转化为α，ω-二叠氮基衍生物。通过催化氢转移还原得到α，ω-二氨基醇。

  DOI：

  10.1016/0040-4039(96)00618-1

文献信息

• A new efficient way to α,ω-diaminoitols by direct azidation of unprotected itols
  作者：V. Glaçon、A. El Meslouti、R. Uzan、G. Demailly、D. Beaupère

  DOI：10.1016/0040-4039(96)00618-1

  日期：1996.5

  Unprotected pentitols and erythritol are transformed into α,ω-diazido derivatives by successive treatment with thionyl chloride and sodium azide. Reduction by catalytic hydrogen transfer gives the α,ω-diaminoitols.

  通过用亚硫酰氯和叠氮化钠相继处理，将未保护的戊糖醇和赤藓糖醇转化为α，ω-二叠氮基衍生物。通过催化氢转移还原得到α，ω-二氨基醇。
• CYCLIC SULFATE COMPOUND, NON-AQUEOUS ELECTROLYTE SOLUTION CONTAINING SAME, AND LITHIUM SECONDARY BATTERY
  申请人：Mio Shigeru

  公开号：US20130171514A1

  公开（公告）日：2013-07-04

  A non-aqueous electrolyte solution containing a cyclic sulfate compound represented by formula (I) is provided, wherein in formula (I), R 1 represents a group represented by formula (II) or a group represented by formula (III); R 2 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms, a group represented by formula (II), or a group represented by formula (III); and in formula (II), R 3 represents a halogen atom, an alkyl group having from 1 to 6 carbon atoms, a halogenated alkyl group having from 1 to 6 carbon atoms, an alkoxy group having from 1 to 6 carbon atoms, or a group represented by formula (IV).

  提供一种含有由式(I)表示的环状硫酸酯化合物的非水电解质溶液，其中在式(I)中，R1表示由式(II)表示的基团或由式(III)表示的基团; R2表示氢原子、具有1至6个碳原子的烷基基团、由式(II)表示的基团或由式(III)表示的基团; 在式(II)中，R3表示卤素原子、具有1至6个碳原子的烷基基团、具有1至6个碳原子的卤代烷基基团、具有1至6个碳原子的烷氧基团或由式(IV)表示的基团。
• Majima; Simanuki, Proceedings of the Imperial Academy (Tokyo), vol. 2, p. 545
  作者：Majima、Simanuki

  DOI：——

  日期：——
• Heterocyclisation of free or partially protected alditols via their bis-cyclic sulfate derivatives. Versatile synthesis of aza and thiodeoxyanhydroalditol with erythro, threo, arabino, gulo, talo or manno configuration
  作者：Virginie Glaçon、Mohammed Benazza、Daniel Beaupère、Gilles Demailly

  DOI：10.1016/s0040-4039(00)00791-7

  日期：2000.6

  The bis-cyclic sulfate derivatives of erythritol (1), D,L-threitol (5), 3,4-di-O-benzyl-D-mannitol (9), 1,2-O-isopropylidene-D-mannitol (14) and 1-O-benzyl-D,L-xylitol (18) were submitted to nucleophilic attack by allylamine or sodium sulfide. In both cases, heterocyclisation occurred and aza or thioanhydrodeoxyalditols were obtained in moderate to good yields (40 to 89%). With compound 9, 1,5-anhydro-5-thio-L-gulitol (12) was obtained as the main product, a result that is in contrast with previous results reported in the literature using bis-epoxide as bielectrophile intermediate.(1) (C) 2000 Published by Elsevier Science Ltd.
• Synthesis of α,ω‐Diazidoalditol Derivatives via Both <i>bis</i>‐ or <i>tris</i>‐Cyclic Sulfites and Peracetylated α,ω‐Dibromoalditols as Bielectrophilic Intermediates
  作者：Virginie Glaçon、Mohammed Benazza、Aniss El Anzi、Daniel Beaupère、Gilles Demailly

  DOI：10.1081/car-120030470

  日期：2004.12.26

  The alpha,omega-diazidoalditol derivatives with erythro, threo, xylo, ribo, D-arabino, D-manno, and D-gluco configuration were efficiently synthesized, respectively, from bis- or tris-cyclic sulfite or peracetylated alpha,omega-dibromoalditol intermediates. The cyclic sulfite intermediates has the advantage to lead directly to the free alpha,omega-diazido-alpha,omega-dideoxyalditols.