N-[2-(2-hydroxyethoxy)ethyl]pentacosa-10,12-diynamide | 1198183-45-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-[2-(2-hydroxyethoxy)ethyl]pentacosa-10,12-diynamide
• CAS: 1198183-45-7
• 化学式: C₂₉H₅₁NO₃
• 分子量: 461.729
• InChiKey: QLIIGZYOBVWGIX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9
• 重原子数：
  33
• 可旋转键数：
  24
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-succinimidyl 10,12-pentacosadiynoic acid ester 、 二甘醇胺 以 二氯甲烷 为溶剂， 反应 3.0h， 以83%的产率得到N-[2-(2-hydroxyethoxy)ethyl]pentacosa-10,12-diynamide
  参考文献：
  名称：

  Probing Temperature on a Microfluidic Chip with Thermosensitive Conjugated Polymer Supramolecules

  摘要：

  DOI：

  10.5012/bkcs.2010.31.6.1753

文献信息

• FUNCTIONALIZED POLYDIACETYLENE SENSORS
  申请人：Kim Jinsang

  公开号：US20110059867A1

  公开（公告）日：2011-03-10

  A microarray includes a solid substrate having a surface, the surface having a plurality of binding spots and a plurality of reaction moieties bound to the binding spots. A reaction moiety includes a plurality of polyacetylene monomers, the polyacetylene monomers having a first coupling region and a second coupling region, the first coupling region having a first functional group operable to bind to the binding spot and the second coupling region comprising a second functional group operable to bind to an accessory molecule; and an accessory molecule having a binding region and an analyte reaction region, the analyte reaction region operable to selectively bind to the target analyte, and the binding region operable to bind to the second coupling region of the polyacetylene monomer. Upon binding a target analyte with the reaction moiety, a color change from the polyacetylene monomer occurs and the reaction moiety produces fluorescence.

  微阵列包括一个固体基质，其表面具有多个结合点和多个与结合点结合的反应分子。反应分子包括多个聚乙烯单体，聚乙烯单体具有第一偶联区和第二偶联区，第一偶联区具有第一个功能基团，可用于结合结合点，第二偶联区包含第二个功能基团，可用于结合辅助分子；以及具有结合区和分析物反应区的辅助分子，分析物反应区可选择性地结合目标分析物，结合区可结合聚乙烯单体的第二偶联区。当反应分子与目标分析物结合时，聚乙烯单体发生颜色变化，反应分子产生荧光。
• Functionalized Polydiacetylene Sensors
  申请人：The Regents of the University of Michigan

  公开号：US20150268232A1

  公开（公告）日：2015-09-24

  A microarray includes a solid substrate having a surface, the surface having a plurality of binding spots and a plurality of reaction moieties bound to the binding spots. A reaction moiety includes a plurality of polyacetylene monomers, the polyacetylene monomers having a first coupling region and a second coupling region, the first coupling region having a first functional group operable to bind to the binding spot and the second coupling region comprising a second functional group operable to bind to an accessory molecule; and an accessory molecule having a binding region and an analyte reaction region, the analyte reaction region operable to selectively bind to the target analyte, and the binding region operable to bind to the second coupling region of the polyacetylene monomer. Upon binding a target analyte with the reaction moiety, a color change from the polyacetylene monomer occurs and the reaction moiety produces fluorescence.

  微阵列包括一个固体基质，其表面具有多个结合点和多个结合点上结合的反应物。反应物包括多个聚乙烯单体，聚乙烯单体具有第一偶合区和第二偶合区，第一偶合区具有可结合结合点的第一功能基团，第二偶合区包括可结合辅助分子的第二功能基团；以及具有结合区和分析物反应区的辅助分子，分析物反应区可选择性地结合目标分析物，结合区可结合聚乙烯单体的第二偶合区。当反应物与目标分析物结合时，聚乙烯单体发生颜色变化，反应物产生荧光。
• US8633140B2
  申请人：——

  公开号：US8633140B2

  公开（公告）日：2014-01-21
• US9523683B2
  申请人：——

  公开号：US9523683B2

  公开（公告）日：2016-12-20
• [EN] A METHOD AND DEVICE FOR MONITORING SUBSTANCES<br/>[FR] PROCÉDÉ ET DISPOSITIF DE SURVEILLANCE DE SUBSTANCES
  申请人：PROTEIN TECHNOLOGIES LTD

  公开号：WO2015128635A1

  公开（公告）日：2015-09-03

  T The present application relates to methods and devices for monitoring a first substance, in particular products and materials such as pharmaceutical products using spectroscopic analysis of labels of a second substance attached to such a first substance so as to authenticate, track and monitor events subsequent to the manufacture of such substances, products and materials at various points in time and at various locations as they pass through the supply chain. The spectral response of the second substance which acts as a label changes as a function of time e.g. also as a function of temperature and may therefore be used to track the (cumulative) history of the first substance since its manufacture assuming the second substance is positioned proximate to the first substance promptly after such manufacture. The conditions which may be monitored via the response of the first substance are e.g. time, temperature, pressure, humidity and changes in atmospheric gases or radiation exposure.