2-丙烯酸,2-辛基癸基酯 | 192181-73-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-丙烯酸,2-辛基癸基酯
• 英文名称: 2-octyldecyl acrylate
• 英文别名: 2-Octyldecyl prop-2-enoate；2-octyldecyl prop-2-enoate
• CAS: 192181-73-0
• 化学式: C₂₁H₄₀O₂
• 分子量: 324.547
• InChiKey: FQHOQFFZHCVKEY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  23
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-丙烯酸,2-辛基癸基酯 、 di-tert-butyl ((9-oxa-3,7-diazabicyclo[3.3.1]nonane-3,7-diyl)bis(butane-4,1-diyl))dicarbamate 在 三乙胺 作用下， 以 异丙醇 为溶剂， 以14.06 %的产率得到tetrakis(2-octyldecyl) 3,3',3”,3”-(((9-oxa-3,7-diazabicyclo[3.3.1]nonane-3,7-diyl)bis(butane-4,1-diyl))bis(azanetriyl))tetrapropionate
  参考文献：
  名称：

  [EN] NOVEL LIPIDS FOR DELIVERY OF NUCLEIC ACID SEGMENTS
  [FR] NOUVEAUX LIPIDES POUR L'ADMINISTRATION DE SEGMENTS D'ACIDE NUCLÉIQUE

  摘要：

  Disclosed herein are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, Y1, X2, Y2, a, b, c, d, e and f are as defined herein. Also disclosed are lipid nanoparticles comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a plurality of lipid nanoparticles comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof and a nucleic acid segment; as well as methods for delivering a nucleic acid segment comprising administering a plurality of lipid nanoparticles comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof, and a nucleic acid segment.

  公开号：

  WO2023073534A1
• 作为产物：
  描述：

  dimethyl 2,2-dioctylmalonate 在 lithium aluminium tetrahydride 、 水 、 三乙胺 、 lithium chloride 作用下， 以 四氢呋喃 、 二氯甲烷 、 二甲基亚砜 为溶剂， 反应 64.0h， 生成 2-丙烯酸,2-辛基癸基酯
  参考文献：
  名称：

  [EN] NOVEL LIPIDS FOR DELIVERY OF NUCLEIC ACID SEGMENTS
  [FR] NOUVEAUX LIPIDES POUR L'ADMINISTRATION DE SEGMENTS D'ACIDE NUCLÉIQUE

  摘要：

  Disclosed herein are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, Y1, X2, Y2, a, b, c, d, e and f are as defined herein. Also disclosed are lipid nanoparticles comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising a plurality of lipid nanoparticles comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof and a nucleic acid segment; as well as methods for delivering a nucleic acid segment comprising administering a plurality of lipid nanoparticles comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof, and a nucleic acid segment.

  公开号：

  WO2023073534A1

文献信息

• COPOLYMER, METHOD FOR PRODUCING THE SAME, OIL REPELLENT COMPOSITION AND ARTICLE PROCESSED WITH THE OIL REPELLENT COMPOSITION
  申请人：Asahi Glass Company, Limited

  公开号：EP2295479A1

  公开（公告）日：2011-03-16

  A copolymer is provided which is capable of providing an article surface with sufficient oil repellency against oils having low surface tensions and which places little burden on the environment. Further, a method for producing such a copolymer, an oil repellent composition containing such a copolymer as an effective component, and an article which is excellent in oil repellency against oils having low surface tensions and which contains no material having high environmental burden, are provided. A copolymer comprising the following polymerized units (a), polymerized units (b), polymerized units (c1) and polymerized units (c2), and an oil repellent composition and article containing it. (a) is polymerized units based on a monomer such as a (meth)acrylate having R1, (b) is polymerized units based on a C6-18 alkyl (meth)acrylate, (c1) is polymerized units based on a monomer having a hydroxy group, and (c2) is polymerized units based on a monomer having a functional group reactive with the hydroxy group in (c1) to form a crosslinked structure.

  本发明提供了一种共聚物，它能够使物品表面对具有低表面张力的油类具有足够的拒油性，并且对环境造成的负担很小。此外，还提供了一种生产这种共聚物的方法、一种含有这种共聚物作为有效成分的驱油组合物，以及一种对表面张力低的油类具有优异驱油性且不含对环境负担高的材料的物品。 一种由以下聚合单元（a）、聚合单元（b）、聚合单元（c1）和聚合单元（c2）组成的共聚物，以及含有该共聚物的驱油组合物和物品。(a)是以具有 R1 的（甲基）丙烯酸酯等单体为基础的聚合单元，(b)是以 C6-18 烷基（甲基）丙烯酸酯为基础的聚合单元，(c1)是以具有羟基的单体为基础的聚合单元，(c2)是以具有与(c1)中的羟基反应形成交联结构的官能团的单体为基础的聚合单元。
• COMPOSITE LIQUID CRYSTAL COMPOSITION, DISPLAY ELEMENT AND ELECTRIC FIELD DETECTOR
  申请人：DIC Corporation

  公开号：EP3034583A1

  公开（公告）日：2016-06-22

  Provided is a composite liquid crystal composition which contains a liquid crystal compound and a polymerizable compound, has sufficiently high Δn, further has high photostability, and can constitute a liquid crystal device capable of being driven at a low voltage. The composite liquid crystal composition includes, as the liquid crystal compound, a compound having a biphenyl skeleton and two or more compounds represented by Formula (I-a), in which the content of the compound having a biphenyl skeleton is 20% by mass or less of the liquid crystal compounds, and the content of the compound represented by Formula (I-a) in which C1 represents a 1, 4-cyclohexylene group and n1 is not 0 is 45% by mass or more of the liquid crystal compounds; and as the polymerizable compound, one or more compounds selected from the compounds represented by Formulas (II-a1) and (II-a2) and a compound represented by (II-b), in which the total content of the liquid crystal compounds is 65% to 85% by mass, and the total content of the polymerizable compounds is 15% to 35% by mass.

  本发明提供了一种复合液晶组合物，它含有一种液晶化合物和一种可聚合化合物，具有足够高的Δn，还具有很高的光稳定性，并可构成一种能在低电压下驱动的液晶器件。复合液晶组合物包括作为液晶化合物的具有联苯骨架的化合物和两种或两种以上由式（I-a）表示的化合物，其中具有联苯骨架的化合物的含量为液晶化合物质量的 20% 或更少，而由式（I-a）表示的化合物（其中 C1 代表 1，4-环己烯基团且 n1 不为 0）的含量为液晶化合物质量的 45% 或更多；作为可聚合化合物，一种或多种选自式 (II-a1) 和 (II-a2) 所代表的化合物以及一种选自式 (II-b) 所代表的化合物，其中液晶化合物的总含量为 65% 至 85%（以质量计），可聚合化合物的总含量为 15%至 35%（以质量计）。
• Dental compositions comprising a fatty mono(meth)acrylate
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US10022306B2

  公开（公告）日：2018-07-17

  Presently described are dental compositions comprising one or more fatty mono(meth)acrylates, methods of use, dental articles, and methods of making dental compositions. It has been found that a relatively low concentration of a fatty mono(meth)acrylate can improve the handling characteristics of a dental composition by reducing the tendency of the composition to stick to a dental instrument and/or by reducing the tendency of a dental composition to string when being manipulated by a dental instrument. In one embodiment, a hardenable dental composition is described comprising a polymerizable resin composition comprising at least one multifunctional ethylenically unsaturated monomer; 0.2 to 10 wt-% of one or more fatty mono(meth)acrylate monomers; and at least 50 wt-% of inorganic oxide filler.

  目前描述的是包含一种或多种脂肪单（甲基）丙烯酸酯的牙科组合物、使用方法、牙科用品和牙科组合物的制造方法。研究发现，相对低浓度的脂肪单（甲基）丙烯酸酯可以改善牙科组合物的操作特性，降低组合物粘附在牙科器械上的倾向和/或降低牙科组合物在牙科器械操作时串连的倾向。在一个实施方案中，描述了一种可硬化牙科组合物，该组合物包含一种可聚合树脂组合物，该树脂组合物包含至少一种多功能乙烯基不饱和单体；0.2-10 wt-%的一种或多种脂肪单（甲基）丙烯酸酯单体；以及至少 50 wt-%的无机氧化物填料。
• Water-based pressure-sensitive adhesive compositions
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US10081745B1

  公开（公告）日：2018-09-25

  A pressure-sensitive adhesive is provided that is a dried product of a latex composition, which is formed from an emulsion composition. The latex composition and the emulsion composition are also provided. The emulsion composition has droplets that contain various monomers plus a (meth)acrylate polymer dissolved in the monomers. Additionally, an article containing a layer of the pressure-sensitive adhesive and a method of forming the pressure-sensitive adhesive are provided. The pressure-sensitive adhesives often have both high peel adhesion and high shear strength (i.e., high cohesive strength or high shear holding power).

  提供了一种压敏胶，它是由乳胶组合物形成的乳胶组合物的干燥产品。此外，还提供了乳胶组合物和乳液组合物。乳液组合物中的液滴含有各种单体和溶解在单体中的（甲基）丙烯酸酯聚合物。此外，还提供了含有一层压敏胶的物品和形成压敏胶的方法。压敏粘合剂通常具有高剥离粘附性和高剪切强度（即高内聚强度或高剪切保持力）。
• Curable adhesive composition, pressure-sensitive adhesive, and the method for making the same
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US10626300B2

  公开（公告）日：2020-04-21

  Curable adhesive compositions that can be used to prepare the pressure-sensitive adhesives, and methods of making the pressure-sensitive adhesives are provided. More particularly, the pressure-sensitive adhesives contain (a) a (meth)acrylate copolymer having a weight average molecular weight greater than 500,000 grams/mole (Daltons), (b) a high glass transition temperature (meth)acrylate polymer tackifier having a Tg of at least 5° C. and (c) a low glass transition temperature (meth)acrylate polymer tackifier having a Tg no greater than 0° C. The pressure-sensitive adhesives advantageously are prepared by ultraviolet (UV) curing a curable adhesive composition that contains minimal or no organic solvents.

  提供了可用于制备压敏粘合剂的可固化粘合剂组合物，以及制造压敏粘合剂的方法。更具体地说，压敏胶包含 (a) 重量平均分子量大于 500,000 克/摩尔（道尔顿）的（甲基）丙烯酸酯共聚物；(b) Tg 至少为 5°C 的高玻璃化转变温度（甲基）丙烯酸酯聚合物增粘剂；以及 (c) 低玻璃化转变温度（甲基）丙烯酸酯聚合物增粘剂。(c) 低玻璃化转变温度（甲基）丙烯酸酯聚合物增粘剂，其 Tg 不大于 0°C。压敏粘合剂可通过紫外线（UV）固化可固化粘合剂组合物来制备，该组合物含有极少量或不含有机溶剂。