Diallyl 3-azaglutarate | 86015-23-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Diallyl 3-azaglutarate
• 英文别名: prop-2-enyl 2-[(2-oxo-2-prop-2-enoxyethyl)amino]acetate
• CAS: 86015-23-8
• 化学式: C₁₀H₁₅NO₄
• 分子量: 213.233
• InChiKey: QBVJGZDMWXISHF-UHFFFAOYSA-N

物化性质

• 沸点：
  282.0±35.0 °C(Predicted)
• 密度：
  1.068±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  64.6
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-甲氨基吡啶 、 丁二酸酐 、 Diallyl 3-azaglutarate 以 氯仿 、 乙酸乙酯 为溶剂， 以51%的产率得到3-(Bis(((allyloxy)carbonyl)methyl)carbamoyl)propanoic acid
  参考文献：
  名称：

  GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY

  摘要：

  这项发明涉及具有与母体糖肽或脂质糖肽抗生素相比具有改变的电离状态的糖肽和脂质糖肽抗生素衍生物，并且具有在生理条件下能够再生为母体糖肽或脂质糖肽抗生素的能力。这些化合物可用作预防和/或治疗细菌感染的抗生素。

  公开号：

  US20120149632A1
• 作为产物：
  描述：

  亚氨基二乙酸 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 以94.6%的产率得到Diallyl 3-azaglutarate
  参考文献：
  名称：

  GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY

  摘要：

  这项发明涉及具有与母体糖肽或脂质糖肽抗生素相比具有改变的电离状态的糖肽和脂质糖肽抗生素衍生物，并且具有在生理条件下能够再生为母体糖肽或脂质糖肽抗生素的能力。这些化合物可用作预防和/或治疗细菌感染的抗生素。

  公开号：

  US20120149632A1

文献信息

• Glycopeptide and lipoglycopeptide antibiotics with improved solubility
  申请人：Rafai Far Adel

  公开号：US08901072B2

  公开（公告）日：2014-12-02

  The invention relates to derivatives of glycopeptide and lipoglycopeptide antibiotics possessing an altered ionization state with respect to the parent glycopeptide or lipoglycopeptide antibiotic, and having the ability to be regenerated as the parent glycopeptide or lipoglycopeptide antibiotic under physiological conditions. These compounds are useful as antibiotics for the prevention and/or the treatment of bacterial infections.

  本发明涉及与母体糖肽或脂肽糖肽抗生素具有不同离子化状态的糖肽衍生物和脂肽糖肽衍生物，并具有在生理条件下再生为母体糖肽或脂肽糖肽抗生素的能力。这些化合物可用作预防和/或治疗细菌感染的抗生素。
• OIL-IN-WATER EMULSION COMPOSITION GEL
  申请人：FUJIFILM Corporation

  公开号：EP3613408A1

  公开（公告）日：2020-02-26

  Provided is a gel-type oil-in-water emulsion composition containing components A to F. A: at least one liquid oil which is selected from the group consisting of a hydrocarbon oil, an aliphatic ester and a silicone oil and a content of which is equal to or greater than 15% by mass with respect to a total amount of the gel-type oil-in-water emulsion composition; B: at least one nonionic surfactant which is selected from the group consisting of a saturated fatty acid glyceryl and a saturated fatty acid polyglyceryl and which has a Hydrophilic-Lipophilic Balance of equal to or smaller than 7; C: a sucrose saturated fatty acid ester; D: an ionic surfactant which has a saturated fatty acid residue as a hydrophobic group and a glutamic acid residue as a hydrophilic group; E: at least one surfactant having an unsaturated fatty acid residue; and F: water.

  本发明提供了一种凝胶型水包油乳液组合物，其中含有 A 至 F 组分。A： 至少一种液态油，选自由烃油、脂肪族酯和硅油组成的组，其含量等于或大于凝胶型水包油乳液组合物总量的 15%（按质量计）； B．至少一种非离子表面活性剂，该表面活性剂选自饱和脂肪酸甘油酯和饱和脂肪酸聚甘油酯组成的组，其亲水-亲油平衡等于或小于 7； C：蔗糖饱和脂肪酸酯； D：离子表面活性剂，该表面活性剂以饱和脂肪酸残基为疏水基团，以谷氨酸残基为亲水基团； E：至少一种具有不饱和脂肪酸残基的表面活性剂；以及 F：水。
• SURFACTANT COMPOSITION FOR FOAMING SAND
  申请人：NOF Corporation

  公开号：EP3981525A1

  公开（公告）日：2022-04-13

  (Object) It is to provide a surfactant composition for foamed sand having excellent rapid-foaming property of the foamed sand and improved strength of a mold when the mold such as a sand core or the like is produced by applying the foamed sand. (Solution) The surfactant composition for a formed sand includes 80 to 99.8 mass% of a compound (A) represented by formula (1); 0.1 to 10 mass% of a compound (B) represented by formula (B); and 0.1 to 10 mass% of an amphoteric surfactant (C).         R1O-(EO)n-SO3M1 ···     (1) (R 1 represents a hydrocarbon group having 6 to 22 carbons, EO represents oxyethylene group, n is 1 to 10, and M 1 represents an alkali metal, an alkaline earth metal, ammonium or an organic ammonium.)         R2O-SO3M2 ····     (2) (R2 represents a hydrocarbon group having 6 to 22 carbons, and M2 represents an alkali metal, an alkaline earth metal, ammonium or an organic ammonium.)

  (目的）提供一种用于发泡砂的表面活性剂组合物，该组合物具有优异的发泡砂快速发泡性能，并且在应用该发泡砂生产砂芯等模具时，可提高模具的强度。 (解决方案）用于成型砂的表面活性剂组合物包括 80 至 99.8 质量％的由式 (1) 表示的化合物 (A)；0.1 至 10 质量％的由式 (B) 表示的化合物 (B)；以及 0.1 至 10 质量％的两性表面活性剂 (C)。 R1O-(EO)n-SO3M1 --- (1) (R 1 代表具有 6 至 22 个碳原子的烃基，EO 代表氧乙烯基，n 为 1 至 10，M 1 代表碱金属、碱土金属、铵或有机铵)。 R2O-SO3M2 ---- (2) (R2 代表具有 6 至 22 个碳原子的烃基，M2 代表碱金属、碱土金属、铵或有机铵)。
• Gel-type oil-in-water emulsion composition
  申请人：FUJIFILM CORPORATION

  公开号：US11197807B2

  公开（公告）日：2021-12-14

  Provided is a gel-type oil-in-water emulsion composition containing components A to F, in which A: at least one liquid oil which is selected from the group consisting of a hydrocarbon oil, an aliphatic ester and a silicone oil and a content of which is equal to or greater than 15% by mass with respect to a total amount of the gel-type oil-in-water emulsion composition; B: at least one nonionic surfactant which is selected from the group consisting of a saturated fatty acid glyceryl and a saturated fatty acid polyglyceryl and which has a Hydrophilic-Lipophilic Balance of equal to or smaller than 7; C: a sucrose saturated fatty acid ester; D: an ionic surfactant which has a saturated fatty acid residue as a hydrophobic group and a glutamic acid residue as a hydrophilic group; E: at least one surfactant having an unsaturated fatty acid residue; and F: water.

  提供了一种胶状的油包水乳液组合物，含有成分 A 至 F，其中： - **A**：至少一种液态油，选自碳氢化合物油、脂肪族酯和硅油中的一种或多种，其含量占胶状油包水乳液组合物总质量的 15% 或更高； - **B**：至少一种非离子型表面活性剂，选自饱和脂肪酸甘油酯和饱和脂肪酸多元醇酯中的一种或多种，并且其亲水-亲油平衡值（HLB值）小于或等于 7； - **C**：一种蔗糖饱和脂肪酸酯； - **D**：一种离子型表面活性剂，其疏水基团为饱和脂肪酸残基，亲水基团为谷氨酸残基； - **E**：至少一种含有不饱和脂肪酸残基的表面活性剂； - **F**：水。
• EP3613408B1
  申请人：——

  公开号：EP3613408B1

  公开（公告）日：2021-02-24