(E)-undec-5-en-2-ol | 144462-99-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-undec-5-en-2-ol
• CAS: 144462-99-7
• 化学式: C₁₁H₂₂O
• 分子量: 170.295
• InChiKey: ACLYYRRLHKOHAO-BQYQJAHWSA-N

物化性质

• 沸点：
  249.8±9.0 °C(Predicted)
• 密度：
  0.844±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-undec-5-en-2-ol 在 pyridinium chlorochromate 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 以88%的产率得到undec-5(E)-en-2-one
  参考文献：
  名称：

  CpRu(CH3CN)3PF6催化的烯炔环异构化中的机械二分法

  摘要：

  由于炔烃的丰富化学性质，炔烃很容易获得结构单元，因此是形成环的有吸引力的底物。用于环异构化的钌催化剂通常在室温下在丙酮或 DMF 中在中性条件下实现 1,6- 和 1,7- 烯炔的此类反应。该反应可有效形成具有广泛发散结构的五元和六元环。炔烃可以带有供选和退选取代基。烯烃可以是二或三取代的。然而，在炔酸的炔丙基位置引入四元中心完全改变了反应的性质。在 1,6-烯酸酯的情况下，在同样温和的条件下以优异的产率形成七元环。提供的证据表明机制发生了完全变化。在前一种情况下，反应涉及钌环戊烯的中间体。在后一种情况下，提出了一个 CH 插入以形成 π-烯丙基钌中间体，并且...

  DOI：

  10.1021/ja012450c
• 作为产物：
  描述：

  undec-5(E)-en-2-one 在 sodium tetrahydroborate 作用下， 生成 (E)-undec-5-en-2-ol
  参考文献：
  名称：

  Organic synthesis using haloboration reaction. Part 7. A stereospecific synthesis of (Z)-.delta.-halo-.gamma.,.delta.-unsaturated ketones via haloboration reaction of terminal alkynes

  摘要：

  DOI：

  10.1021/ja00304a032

文献信息

• New Modes for the Osmium-Catalyzed Oxidative Cyclization
  作者：Timothy J. Donohoe、Peter J. Lindsay-Scott、Jeremy S. Parker、Cedric K. A. Callens

  DOI：10.1021/ol100046a

  日期：2010.3.5

  The osmium-catalyzed oxidative cyclization of amino alcohol initiators formally derived from 1,4-dienes is an effective method for the construction of pyrrolidines, utilizing a novel reoxidant (4-nitropyridine N-oxide = NPNO). The cyclization of enantiopure syn- and anti-amino alcohols gives rise to enantiopure cis- and trans-2,5-disubstituted pyrrolidines, respectively. Moreover, the cyclization of

  形式上衍生自1,4-二烯的氨基醇引发剂的os催化氧化环化是一种利用新型再氧化剂（4-硝基吡啶N-氧化物= NPNO）构建吡咯烷的有效方法。对映体纯的顺式和反式氨基醇的环化分别产生对映体纯的顺式和反式-2,5-二取代的吡咯烷。此外，显示带有环外螯合基团的双-均烯丙基胺的环化是反式-吡咯烷形成的补充方法。
• COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME
  申请人：Komatsuki Yasuhiro

  公开号：US20110081393A1

  公开（公告）日：2011-04-07

  Disclosed is a cooling sensation agent composition or sensory stimulation agent composition which contains at least one of diester compounds of dicarboxylic acid represented by the formula (1) wherein A represents CH 2 or CH═CH, n represents an integer of 0 to 4 when A is CH 2 , or 1 when A is CH═CH, B is an alcohol residue having 10 to 18 carbon atoms and containing a para-menthane skeleton, which may have a substituent, and C is an alcohol residue having 6 to 18 carbon atoms, which may have a substituent as well as a flavor or fragrance composition, a beverage, a food product, a perfume or cosmetic product, a toiletry product, daily utensil products or groceries, a fiber, a fiber product, clothes, clothing or a medicine, wherein the cooling sensation agent composition or the sensory stimulation agent composition is compounded.

  本文披露了一种包含以下化学式（1）所代表的二羧酸双酯化合物之一的冷却感剂组合物或感官刺激剂组合物，其中A代表CH2或CH═CH，n代表整数0至4（当A为CH2时）或1（当A为CH═CH时），B是含有10至18个碳原子并含有对蒎烷骨架的醇残基，可能有取代基，C是含有6至18个碳原子的醇残基，可能也有取代基，以及香料或香精组合物、饮料、食品产品、香水或化妆品产品、洗涤用品、日用品或杂货、纤维、纤维制品、衣服、服装或药品，其中复合了冷却感剂组合物或感官刺激剂组合物。
• Oxidative cyclization of 5-hydroxyalkenes with rhenium oxide, utilizing a co-oxidant. IV
  作者：Suhan Tang、Robert M. Kennedy

  DOI：10.1016/s0040-4039(00)79078-2

  日期：1992.9

  5-Hydroxylalkenes react with rhenium(VII) oxide in the presence of another oxidant, H5IO6, to provide substituted tetrahydrofurans. The yield and stereoselectivity are comparable to stoichiometric results.

  5-羟基烯烃与氧化rh（VII）在另一种氧化剂H 5 IO 6的存在下反应，提供取代的四氢呋喃。产率和立体选择性与化学计量结果相当。
• Tandem dienyne ring-closing metathesis of alkynyl silaketals for the formation of bicyclic siloxanes
  作者：Jonathan B. Grimm、Ryan D. Otte、Daesung Lee

  DOI：10.1016/j.jorganchem.2005.04.037

  日期：2005.12

  The tandem dienyne ring-closing metathesis of alkynyl silaketals containing two tethered olefins was achieved with second generation Grubbs NHC-ruthenium carbene complex to provide bicyclic siloxanes in good to excellent yield. Silaketals synthesized from homoallylic or bishomoallylic alcohols via base-catalyzed alcoholysis of trialkynylsilanes were well tolerated in the metathesis process and generated ring systems of various sizes. Removal of the silicon tether was achieved through protodesilylation with fluoride to afford stereochemically defined (1E,3Z)-dienes. (c) 2005 Elsevier B.V. All rights preserved.
• COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION
  申请人：Ishida Kenya

  公开号：US20110117147A1

  公开（公告）日：2011-05-19

  The invention relates to a cooling sensation agent composition with a prolonged cool sensation effect comprising at least one compound selected from Formula (1) wherein each of A and B is a hydrogen atom or a hydrocarbon group which may have one or more substituents, in which A and B are not hydrogen atoms simultaneously, and the total number of carbon atoms in A and B is in the range of 6 to 18; and Formulae (2) to (4) wherein R1, R2, and R3 each represent a residue of an alcohol selected from 1-menthol, 1-isopulegol, 3-(1-menthoxy)propan-1,2-diol, 2-(1-menthoxy)ethan-1-ol, 3-(1-menthoxy)propan-1-ol, 2-methyl-3-(1-menthoxy)propan-1,2-diol and para-menthan-3,8-diol), and R4 represents a residue of a branched or straight-chain, cyclic or linear, or saturated or unsaturated alcohol having 6 to 18 carbon atoms that may have one or more aromatic rings that may have a condensed ring and substituent groups such as hydroxyl and ether groups; and R6 represents a hydrocarbon group having 11 to 19 carbon atoms that may be branched and contain one or more unsaturated bonds. The invention also relates to a sensory stimulation agent composition comprising the cooling sensation agent composition; a flavor or fragrance composition, a beverage or food product, a perfume or cosmetic product, a toiletry product, a daily utensil product or grocery, a fiber, a fiber product, a cloth or a medicine comprising the cooling sensation agent composition or the sensory stimulation agent composition; a production method thereof; a cooling processing method of a fiber, fiber product or a cloth, comprising compounding the cooling sensation agent composition or the sensory stimulation agent composition; and new compounds.