ethyl 3-fluoro-2-(phenylselenyl)butanoate | 1131125-58-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl 3-fluoro-2-(phenylselenyl)butanoate
• 英文别名: Ethyl 3-fluoro-2-phenylselanylbutanoate
• CAS: 1131125-58-0
• 化学式: C₁₂H₁₅FO₂Se
• 分子量: 289.208
• InChiKey: WPWMMNAHIMZOPA-UHFFFAOYSA-N

物化性质

• 沸点：
  336.2±42.0 °C(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.73
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  二苯基二硒醚 、 反式-2-丁烯酸乙酯 在 triethylamine pentahydrogen fluoride salt 作用下， 以 硝基甲烷 为溶剂， 以71%的产率得到ethyl 3-fluoro-2-(phenylselenyl)butanoate
  参考文献：
  名称：

  Electrochemical fluoro-selenenylation of electron-deficient olefins

  摘要：

  Electrochemical fluoro-selenenylation of electron-deficient olefins like a,p-unsaturated ester, carboxylic acid, amide, and phosphonate was successfully carried out by the anodic oxidation of diphenyl diselenide in the presence of olefins in Et3N center dot 5HF/CH3NO2. The anodically generated benzeneselenenyl fluoride [PhSeF] equivalent was stable in the electrolytic solution, which resulted in the efficient fluoro-selenenylation. The fluoro-selenenylation products were shown to be potential useful fluoro-building blocks. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.12.068

文献信息

• Electrochemical fluoro-selenenylation of electron-deficient olefins
  作者：Hirokatsu Nagura、Shinsuke Inagi、Toshio Fuchigami

  DOI：10.1016/j.tet.2008.12.068

  日期：2009.2

  Electrochemical fluoro-selenenylation of electron-deficient olefins like a,p-unsaturated ester, carboxylic acid, amide, and phosphonate was successfully carried out by the anodic oxidation of diphenyl diselenide in the presence of olefins in Et3N center dot 5HF/CH3NO2. The anodically generated benzeneselenenyl fluoride [PhSeF] equivalent was stable in the electrolytic solution, which resulted in the efficient fluoro-selenenylation. The fluoro-selenenylation products were shown to be potential useful fluoro-building blocks. (C) 2008 Elsevier Ltd. All rights reserved.