pyrrole-2,3,4,5-tetracarboxylic acid | 954-18-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: pyrrole-2,3,4,5-tetracarboxylic acid
• 英文别名: Pyrrol-2,3,4,5-tetracarbonsaeure；1H-pyrrole-2,3,4,5-tetracarboxylic acid
• CAS: 954-18-7
• 化学式: C₈H₅NO₈
• 分子量: 243.13
• InChiKey: VRAMBVNDRDGAQP-UHFFFAOYSA-N

物化性质

• 熔点：
  >300 °C
• 沸点：
  699.5±55.0 °C(Predicted)
• 密度：
  2.062±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  165
• 氢给体数：
  5
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  pyrrole-2,3,4,5-tetracarboxylic acid 在 盐酸 作用下， 生成 tetramethyl 1H-pyrrole-2,3,4,5-tetracarboxylate
  参考文献：
  名称：

  Nicolaus; Oriente, Gazzetta Chimica Italiana, 1954, vol. 84, p. 230,237

  摘要：

  DOI：
• 作为产物：
  描述：

  草酰乙酸二乙酯 在 溶剂黄146 、 sodium nitrite 作用下， 生成 pyrrole-2,3,4,5-tetracarboxylic acid
  参考文献：
  名称：

  Vitale et al., Rendiconto dell'Accademia delle Scienze Fisiche e Matematiche, Naples, 1959, vol. <4> 26, p. 267,269

  摘要：

  DOI：

文献信息

• Catalyst compositions and catalytic processes
  申请人：PHILLIPS PETROLEUM COMPANY

  公开号：EP0603557A1

  公开（公告）日：1994-06-29

  Catalytic compositions and catalytic processes are provided. The catalytic compositions are produced by the process that comprises contacting an organonickel compound with a cyclicazacarbyl compound. Optionally, one or more catalytic promoters can be present in the catalytic compositions. Additionally, one or more olefins can be contacted with one or more of these catalytic compositions to form oligomerization products and/or polymerization products.

  提供了催化组合物和催化工艺。催化组合物是通过将有机镍化合物与环氮羰基化合物接触的工艺生产的。催化组合物中可任选存在一种或多种催化促进剂。此外，一种或多种烯烃可与一种或多种这些催化组合物接触，以形成低聚产物和/或聚合产物。
• Quantification of Naturally Occurring Pyrrole Acids in Melanosomes
  作者：Weslyn C. Ward、Erin C. Lamb、David Gooden、Xin Chen、David J. Burinsky、John D. Simon

  DOI：10.1111/j.1751-1097.2008.00328.x

  日期：2008.5

  AbstractThree naturally occurring pyrrole acids were found in Sepia, human black hair, and bovine choroid and iris melanosomes using high‐performance liquid chromatography and mass spectrometry—pyrrole‐2,3‐dicarboxylic acid (PDCA), pyrrole‐2,3,5‐tricarboxylic acid (PTCA) and pyrrole‐2,3,4,5‐tetracarboxylic acid (PTeCA). PDCA and PTCA are common markers quantified from oxidative degradation of eumelanins. Using standards, the amounts of naturally occurring PDCA and PTCA were determined and compared to those obtained following peroxide oxidation of the same samples. Because the naturally occurring acids are water soluble, these results indicate that care must be exercised when comparing PDCA and PTCA yields from the degradation analyses of melanins isolated and prepared by different methods. This work also establishes that PTeCA is a naturally occurring pyrrole acid in melanosomes.
• Nicolaus; Mangoni, Annali di Chimica, 1956, vol. 46, p. 847,854
  作者：Nicolaus、Mangoni

  DOI：——

  日期：——
• Reactions of benzo and dibenzo derivatives of five-membered aromatic heterocycles with ozone in the liquid phase
  作者：P. Yu. Andreev

  DOI：10.1134/s0965544115020036

  日期：2015.7

  The ozonation reactions of benzo and dibenzo derivatives of pyrrole, furan, and thiophene in acetic acid solution have been studied. Peroxide compounds have been detected as the products. The mechanism of ozone interaction with these hetarenes has been proposed. The kinetics of ozonolytic reactions of benzologues of five-membered aromatic heterocycles (hetarenes) have been investigated. The reaction of ozone with the hetarenes obeys the bimolecular rate law and has the first order in each reactant. The effective rate constants and experimental stoichiometric coefficients for ozone have been found.
• US5332708A
  申请人：——

  公开号：US5332708A

  公开（公告）日：1994-07-26