disodium thioglycolate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: disodium thioglycolate
• 英文别名: Sodium;2-sulfidoacetate；sodium;2-sulfidoacetate
• 化学式: C₂H₂O₂S*2Na
• 分子量: 136.082
• InChiKey: GNBVPFITFYNRCN-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -4.71
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  41.1
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  dibenzo-1,2-dithiin 1,1-dioxide 、 disodium thioglycolate 在 sodium methylate 作用下， 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  Srivastava, P. K.; Chandra, Ramesh; Gupta, Madhu Bala, Journal of the Indian Chemical Society, 1983, vol. 60, p. 570 - 571

  摘要：

  DOI：

文献信息

• Synthesis of some Sulfur-Containing Acylferrocenes
  作者：Rastko D. Vukićević、Danijela Ilić、Zoran Ratković、Mirjana Vukićević

  DOI：10.1007/s007060170099

  日期：2001.5.21

   Acylferrocenes containing a sulfur atom within their side chain were synthesized in good yields by Friedel-Crafts acylation of ferrocene with in situ generated acyl halides from the corresponding carboxylic acids (S-protected derivatives of thioglicolic and α- and β-mercaptopropionic acids).

   通过将二茂铁与相应羧酸的 原位 生成的酰基卤化物进行 Friedel-Crafts 酰化反应，可以高收率合成在其侧链中含有硫原子的 酰基二茂铁 （S-保护的巯基乙酸和α-和β-巯基丙酸衍生物）。
• α,β-Epoxy Sulfoxides as Useful Intermediates in Organic Synthesis. II. A Novel Synthesis of α-Sulfenylated Ketones and α-Sulfenylated Aldehydes from α,β-Epoxy Sulfoxides
  作者：Tsuyoshi Satoh、Takumi Kumagawa、Koji Yamakawa

  DOI：10.1246/bcsj.58.2849

  日期：1985.10

  Treatment of α,β-epoxy sulfoxides, prepared from 1-chloroalkyl phenyl sulfoxides and carbonyl compounds, with various kinds of alkane- or arenethiolates afforded α-sulfenylated ketones in good yields. This method also offered a novel procedure for a synthesis of α-sulfenylated aldehydes.

  用各种烷烃或芳烃硫醇盐处理由 1-氯代烷基苯基亚砜和羰基化合物制备的 α,β-环氧亚砜，可以得到高产率的 α-亚磺酰化酮。该方法还提供了一种合成 α- 磺基化醛的新方法。
• One-Step Assembly of Carbamoyl-Substituted Heteroannelated [1,4]Thiazepines
  作者：Alexey P. Ilyn、Marina V. Loseva、Vladimir Y. Vvedensky、Elena B. Putsykina、Sergey E. Tkachenko、Dmitri V. Kravchenko、Alexandr V. Khvat、Mikhail Y. Krasavin、Alexandre V. Ivachtchenko

  DOI：10.1021/jo052640w

  日期：2006.3.31

  We present a convenient synthesis of novel heteroaryl-fused 3-oxo-1,4-thiazepine-5-carboxamides and 5-oxo-1,4-thiazepine-3-carboxamides using a modification of four-component Ugi condensation. We demonstrate the usefulness and versatility of the developed approach for the synthesis of variously substituted compounds and discuss the scope and limitations of the chemistry involved.

  我们提出了一种新颖的杂芳基融合的3-oxo-1,4-thiazepine-5-carboxamides和5-oxo-1,4-thiazepine-3-carboxamides的方便合成，使用四组分Ugi缩合修饰。我们证明了开发的方法用于合成各种取代的化合物的实用性和多功能性，并讨论了所涉及化学的范围和局限性。
• A NOVEL SYNTHESIS OF DIALKYL KETONES AND α-SULFENYLATED CARBONYL COMPOUNDS FROM α,β-EPOXY SULFOXIDES
  作者：Tsuyoshi Satoh、Youhei Kaneko、Takumi Kumagawa、Takao Izawa、Kiichi Sakata、Koji Yamakawa

  DOI：10.1246/cl.1984.1957

  日期：1984.11.5

  Treatment of α,β-epoxy sulfoxides with excess sodium phenylselenide and various kinds of alkylthiolates gave dialkyl ketones and α-sulfenylated carbonyl compounds, respectively, in good yields under mild conditions.

  用过量的苯硒化钠和各种烷基硫醇化物处理 α,β-环氧亚砜，分别在温和条件下以良好的产率得到二烷基酮和 α-亚磺酰化羰基化合物。
• The Thin Film of Fluorine-containing Polymer Having Cyclodextrin Prepared by Langmuir-Blodgett Technique
  作者：Masanori Tamura、Akira Sekiya

  DOI：10.1246/cl.1992.1313

  日期：1992.7

  Polyallylamine modified with perfluoroalkyl groups was spread by Langmuir-Blodgett technique and reacted on the aqueous solution of a cyclodextrin derivative. The cyclodextrin moiety was first introduced to the thin film of fluorine-containing polymer. The film of the polymer having the cyclodextrin moiety was characterized.

  用全氟烷基改性的聚烯丙胺通过Langmuir-Blodgett技术展开并在环糊精衍生物的水溶液上反应。环糊精部分首先被引入到含氟聚合物的薄膜中。表征具有环糊精部分的聚合物膜。