2-(2-methyl-4-ethylthiazole-5-carboxamido)-2-(2-furyl)acetonitrile | 119778-32-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(2-methyl-4-ethylthiazole-5-carboxamido)-2-(2-furyl)acetonitrile
• 英文别名: N-[cyano(furan-2-yl)methyl]-4-ethyl-2-methyl-1,3-thiazole-5-carboxamide
• CAS: 119778-32-4
• 化学式: C₁₃H₁₃N₃O₂S
• 分子量: 275.331
• InChiKey: VKTVVRHLBBVSHQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  107
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  amino(furan-2-yl)acetonitrile 生成 2-(2-methyl-4-ethylthiazole-5-carboxamido)-2-(2-furyl)acetonitrile
  参考文献：
  名称：

  SIMOTORI, XITOSI;YANAGISEH, YUDZI;SEHKINO, TAKEHSI;SINADA, KEHJKO;KANEHMO+

  摘要：

  DOI：

文献信息

• Amide derivatives, and their production and agricultural fungicides
  申请人：Sumitomo Chemical Company Limited

  公开号：US04918089A1

  公开（公告）日：1990-04-17

  An amide compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are, the same or different, each a hydrogen atom or a C.sub.1 -C.sub.3 alkyl group and R.sup.3 is a 2-furyl group, a 3-furyl group, a 2-thienyl group or a 3-thienyl group, which is useful as an agricultural fungicide.

  一种酰胺化合物，其化学式为：##STR1##其中R.sup.1和R.sup.2是相同或不同的氢原子或C.sub.1-C.sub.3烷基，R.sup.3是2-呋喃基，3-呋喃基，2-噻吩基或3-噻吩基，可用作农业杀菌剂。
• Benzimidazole derivatives, a method for producing the same, agricultural and horticultural fungicides containing the same as an active ingredient and intermediate compounds thereof
  申请人：SUMITOMO CHEMICAL COMPANY LIMITED

  公开号：EP0517476A2

  公开（公告）日：1992-12-09

  A benzimidazole derivative having the formula, wherein R is cyano or thiocarbamoyl; Q is lower alkyl or a group represented by the formula NQ¹Q², in which Q¹ and Q² are independently lower alkyl, lower alkyl substituted with phenyl, lower alkenyl or lower alkynyl, or they form a lower alkylene ring when taken together at their ends which ring may include a hetero atom; X is hydrogen or halogen; and Z is a group which consists of (a) one oxygen atom or two non-adjacent oxygen atom, (b) -CF₂- group and (c) any one of a single bond, -CF₂-, -CFH-, CFCl- and -CH₂- groups and forms a five-membered or six membered ring together with two adjacent carbon atoms of the benzene ring; is obtained by reacting a corresponding 2-cyanobenzimidazole compound and a sulfamoyl chloride derivative. The benzimidazole derivative is incorporated into agricultural and horticultural fungicides as an active ingredient.

  具有以下式子的苯并咪唑衍生物 其中 R 是氰基或硫代氨基甲酰基；Q 是低级烷基或由式 NQ¹Q² 所代表的基团，其中 Q¹ 和 Q² 独立地是低级烷基、被苯基取代的低级烷基、低级烯基或低级炔基，或者当它们在两端结合在一起时形成一个低级亚烷基环，该环可包括一个杂原子；X 是氢或卤素；和 Z 是由(a)一个氧原子或两个不相邻的氧原子、(b)-CF₂- 基团和(c)单键、-CF₂-、-CFH-、CFCl- 和-CH₂- 基团中的任意一个组成的基团，并与苯环的两个相邻碳原子一起形成五元环或六元环。苯并咪唑衍生物可作为活性成分加入农用和园艺杀菌剂中。
• KUSABA, TOMOYUKI;SHINSUGI, KAZUE;KATOH, TSUGUHIRO;MEKI, NAOTO;SUGANO, MAS+
  作者：KUSABA, TOMOYUKI、SHINSUGI, KAZUE、KATOH, TSUGUHIRO、MEKI, NAOTO、SUGANO, MAS+

  DOI：——

  日期：——
• Amide derivatives, and their production and agricultural fungicides containing them
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0292937B1

  公开（公告）日：1994-08-10
• US4918089A
  申请人：——

  公开号：US4918089A

  公开（公告）日：1990-04-17