2-己基癸酸甲酯 | 54889-76-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 2-己基癸酸甲酯
• 英文名称: methyl 2-hexyldecanoate
• 英文别名: D,L-2-Hexyl-decansaeure-methylester；Methyl-2-hexyl-decanoat
• CAS: 54889-76-8
• 化学式: C₁₇H₃₄O₂
• 分子量: 270.456
• InChiKey: PBRCCXNUTAGYJI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915900090

反应信息

• 作为反应物：
  描述：

  2-己基癸酸甲酯 在 lithium aluminium tetrahydride 、 氢溴酸 作用下， 以 四氢呋喃 为溶剂， 反应 7.0h， 生成 1-溴-2-己基癸烷
  参考文献：
  名称：

  Baarschers, Willem Hendrik; Li, Maria Angela, Canadian Journal of Chemistry, 1983, vol. 61, p. 1784 - 1787

  摘要：

  DOI：
• 作为产物：
  描述：

  hexyl-octylmalonic acid 在 glass powder 作用下， 以 乙醚 为溶剂， 反应 3.5h， 生成 2-己基癸酸甲酯
  参考文献：
  名称：

  Baarschers, Willem Hendrik; Li, Maria Angela, Canadian Journal of Chemistry, 1983, vol. 61, p. 1784 - 1787

  摘要：

  DOI：

文献信息

• [EN] IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY<br/>[FR] LIPIDES IONISABLES POUR L'ADMINISTRATION D'ACIDES NUCLÉIQUES
  申请人：PREC NANOSYSTEMS INC

  公开号：WO2021000041A1

  公开（公告）日：2021-01-07

  The present document describes compounds, or pharmaceutically acceptable salt thereof, of a core formula (I) Wherein R1 includes an amino group. These compounds are particularly useful in the formulation and in vivo and ex vivo delivery of nucleic acid and protein therapeutics for preparing and implementing T cell transfection, gene editing, cancer therapies, cancer prophylactics, and in the preparation of vaccines.

  本文件描述了核心公式（I）的化合物或其药用可接受盐，其中R1包括氨基团。这些化合物在核酸和蛋白治疗剂的制剂、体内和体外递送中特别有用，用于制备和实施T细胞转染、基因编辑、癌症治疗、癌症预防以及疫苗的制备。
• Palladium/IzQO-Catalyzed Coordination–Insertion Copolymerization of Ethylene and 1,1-Disubstituted Ethylenes Bearing a Polar Functional Group
  作者：Hina Yasuda、Ryo Nakano、Shingo Ito、Kyoko Nozaki

  DOI：10.1021/jacs.7b12593

  日期：2018.2.7

  Coordination-insertion copolymerization of ethylene with 1,1-disubstituted ethylenes bearing a polar functional group, such as methyl methacrylate (MMA), is a long-standing challenge in catalytic polymerization. The major obstacle for this process is the huge difference in reactivity of ethylene versus 1,1-disubstituted ethylenes toward both coordination and insertion. Herein we report the copolymerization of ethylene

  乙烯与带有极性官能团的 1,1-二取代乙烯（如甲基丙烯酸甲酯 (MMA)）的配位插入共聚是催化聚合中长期存在的挑战。该过程的主要障碍是乙烯与 1,1-二取代乙烯在配位和插入方面的反应性存在巨大差异。在此，我们报告了使用咪唑并 [1,5-a] quinolin-9-olate-1-ylidene-supported 钯催化剂共聚乙烯和 1,1-二取代乙烯。各种类型的 1,1-二取代乙烯成功地结合到聚乙烯链中。
• NON-AQUEOUS COMPOSITIONS CONTAINING NANOSIZED PARTICLES OF MONOAZO LAKED PIGMENT
  申请人：CARLINI Rina

  公开号：US20080306189A1

  公开（公告）日：2008-12-11

  Non-aqueous disperson compositions, such as ink compositions, contain a polymeric dispersant, a polymeric resin, an organic liquid, and a nanoscale pigment particle composition including an organic monoazo laked pigment including at least one functional moiety, and a sterically bulky stabilizer compound including at least one functional group, wherein the functional moiety of the pigment associates non-covalently with the functional group of the stabilizer; and the presence of the associated stabilizer limits the extent of particle growth and aggregation, to afford nanoscale-sized pigment particles.
• Radiation Curable Compositions Containing Nanosized Particles Of Monoazo Laked Pigment
  申请人：ALLEN C. Geoffrey

  公开号：US20080306193A1

  公开（公告）日：2008-12-11

  Radiation curable compositions, such as UV curable ink compositions, contain a polymeric dispersant, a curable material, and a nanoscale pigment particle composition including an organic monoazo laked pigment including at least one functional moiety, and a sterically bulky stabilizer compound including at least one functional group, wherein the functional moiety of the pigment associates non-covalently with the functional group of the stabilizer; and the presence of the associated stabilizer limits the extent of particle growth and aggregation, to afford nanoscale-sized pigment particles.
• RADIATION CURABLE INK CONTAINING FLUORESCENT NANOPARTICLES
  申请人：IFTIME Gabriel

  公开号：US20100086701A1

  公开（公告）日：2010-04-08

  Radiation curable compositions, such as UV curable ink compositions, contain a polymeric dispersant, a curable material, that includes a carrier and at least one nanoscale fluorescent pigment particle and an optional non-fluorescent colorant. The fluorescent organic nanoparticle composition includes one or more fluorescent dyes dispersed in a polymeric matrix obtained by modified EA latex process or by emulsion polymerization. In a different embodiment, the nanoscale fluorescent pigment particle composition includes pigment molecules with at least one functional moiety, and a sterically bulky stabilizer compound including at least one functional group, the functional moiety of the pigment associates non-covalently with the functional group of the stabilizer, and the presence of the associated stabilizer limits the extent of particle growth and aggregation, to afford nanoscale-sized pigment particles.