3,3-diphenyl-1,2-indanedione Z-4,4-dimethyl-1-thiosemicarbazone | 120242-79-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: 3,3-diphenyl-1,2-indanedione Z-4,4-dimethyl-1-thiosemicarbazone
• 英文别名: 1,1-dimethyl-3-[(Z)-(2-oxo-3,3-diphenylinden-1-ylidene)amino]thiourea
• CAS: 120242-79-7
• 化学式: C₂₄H₂₁N₃OS
• 分子量: 399.516
• InChiKey: KVIFMIFUGAASDS-DAFNUICNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  76.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4,4-二甲基-3-氨基硫脲单水合物 、 3,3-diphenyl-1,2-indanedione 在 溶剂黄146 作用下， 反应 5.0h， 以74.9%的产率得到3,3-diphenyl-1,2-indanedione Z-4,4-dimethyl-1-thiosemicarbazone
  参考文献：
  名称：

  Tomchin, A. B.; Marysheva, V. V., Journal of Organic Chemistry USSR (English Translation), 1988, vol. 24, p. 1648 - 1654

  摘要：

  DOI：

文献信息

• TOMCHIN, A. B.;MARYSHEVA, V. V., ZH. ORGAN. XIMII, 24,(1988) N 9, S. 1827-1835
  作者：TOMCHIN, A. B.、MARYSHEVA, V. V.

  DOI：——

  日期：——
• Inhibitor for V-Atpase Activity, Antibacterial Agent, Medicine, Antibacterial Method and Screening Method
  申请人：Japan Science and Technology Agency

  公开号：US20220105076A1

  公开（公告）日：2022-04-07

  An inhibitor for Na + -translocating V-ATPase activity including a compound represented by where R 1 represents a group selected from a hydroxy group, an alkoxy group, and a haloalkoxy group, each bonded to an adjacent phenyl group via oxygen, or a group selected from a dialkylamino group, a heterocyclic amine, and a carboxylic acid amide group, each bonded to an adjacent phenyl group via nitrogen, or represents bromine, iodine, or a straight-chain hydrocarbon group. R 2 represents hydrogen or a haloalkoxy group. Z 1 represents an aliphatic hydrocarbon group, an alicyclic hydrocarbon group, an aromatic hydrocarbon group, or a heterocyclic group, each optionally having an arbitrary substituent and having a structure containing a double bond selected from between the group and an adjacent phenyl group. The symbol * represents a bond to the adjacent phenyl group.
• Tomchin, A. B.; Marysheva, V. V., Journal of Organic Chemistry USSR (English Translation), 1988, vol. 24, p. 1648 - 1654
  作者：Tomchin, A. B.、Marysheva, V. V.

  DOI：——

  日期：——