1,7-heptanediol dipropenoate | 61804-12-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,7-heptanediol dipropenoate
• 英文别名: heptane-1,7-diyl diacrylate；7-Prop-2-enoyloxyheptyl prop-2-enoate
• CAS: 61804-12-4
• 化学式: C₁₃H₂₀O₄
• 分子量: 240.299
• InChiKey: CKDIBPOOPFHEAK-UHFFFAOYSA-N

物化性质

• 沸点：
  110-113 °C(Press: 0.03 Torr)
• 密度：
  1.000±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  17
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,7-heptanediol dipropenoate 在 disodium hydrogenphosphate 、 双氧水 、 三氟乙酸酐 作用下， 以 二氯甲烷 、 异丙醇 为溶剂， 反应 51.0h， 生成 7-[3-[6,7-dimethoxy-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-2-hydroxypropanoyl]oxyheptyl 3-[6,7-dimethoxy-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-2-hydroxypropanoate
  参考文献：
  名称：

  Neuromuscular blocking agents. Some approaches to short acting compounds

  摘要：

  A series of amidic and N-methylamidic methyl and trideuteromethyl quaternary analogues of atracurium have been prepared. All were less potent and longer acting neuromuscular blocking agents than atracurium, and all showed appreciable vagal blockade at neuromuscular blocking doses. Replacement of NCH3 by NCD3 failed to affect potency. Fluorosubstitution in the central chain did not reduce duration of action. Attachment of acyloxy substituents to the interquaternary chain of atracurium and related compounds adjacent to their ester groups shortened the duration of action significantly. Diformyloxy substitution was the most effective in reducing duration without adversely affecting other properties apart from potency, which was significantly less than that of atracurium.

  DOI：

  10.1016/0223-5234(92)90180-9
• 作为产物：
  描述：

  1,7-庚二醇 、 丙烯酰氯 在 三乙胺 、 邻苯三酚 作用下， 以 苯 为溶剂， 反应 0.5h， 以62%的产率得到1,7-heptanediol dipropenoate
  参考文献：
  名称：

  Stenlake; Waigh; Dewar, European Journal of Medicinal Chemistry, 1981, vol. 16, # 6, p. 515 - 524

  摘要：

  DOI：

文献信息

• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• COMPOSITE SEMIPERMEABLE MEMBRANE AND METHOD FOR PRODUCING SAME
  申请人：Toray Industries, Inc.

  公开号：EP2650044A1

  公开（公告）日：2013-10-16

  Provided is a composite semipermeable membrane comprising a microporous support membrane and a separation functional layer formed thereon, wherein the separation functional layer is formed from Compound (A) in which a reactive group(s) having an ethylenically unsaturated group and a hydrolyzable group(s) are bonded directly to a silicon atom, Compound (B) having an ethylenically unsaturated group, the Compound (B) being different from said Compound (A), and Compound (C) having an ethylenically unsaturated group, the Compound (C) being different from said Compound (A) and (B), by condensation of hydrolyzable groups that the Compound (A) has and polymerization of ethylenically unsaturated groups that the Compound (A), the Compound (B), and the Compound (C) have, and the Compound (A), the Compound (B), and the Compound (C) satisfy the relationship of the following equation (I): QA-QC+QB-QC=QA-QB (Qx represents an Alfrey-Price Q value of Compound X). A composite semipermeable membrane having excellent chemical resistivity to chemicals represented by chlorine, separation performance, and water permeability can be provided.

  提供了一种复合半透膜，包括微孔支撑膜和在其上形成的分离功能层，其中分离功能层由以下化合物形成：化合物（A），其中具有乙烯不饱和基团的反应基团和可水解基团直接键合到硅原子上；化合物（B），具有乙烯不饱和基团，所述化合物（B）不同于所述化合物（A）；以及化合物（C），具有乙烯不饱和基团，所述化合物（C）不同于所述化合物（A）和（B）、化合物（A）具有的可水解基团和化合物（A）、化合物（B）和化合物（C）具有的乙烯基不饱和基团的缩合，以及化合物（A）、化合物（B）和化合物（C）具有的乙烯基不饱和基团的聚合，以及化合物（A）、化合物（B）和化合物（C）具有的乙烯基不饱和基团的聚合，满足下式（I）的关系：QA-QC+QB-QC=QA-QB (Qx 代表化合物 X 的 Alfrey-Price Q 值）。 可以提供一种复合半透膜，它对以氯为代表的化学物质具有极佳的耐化学性、分离性能和透水性。
• STENLAKE, J. B.;WAIGH, R. D.;DEWAR, G. H.;HUGHES, R.;CHAPPLE, D. J.;COKER+, EUR. J. MED. CHEM.-CHIM. THER., 1981, 16, N 6, 515-524
  作者：STENLAKE, J. B.、WAIGH, R. D.、DEWAR, G. H.、HUGHES, R.、CHAPPLE, D. J.、COKER+

  DOI：——

  日期：——
• Protective coating material
  申请人：Tosoh Corporation

  公开号：EP0482557B1

  公开（公告）日：1994-06-15