2,5-bis(hex-1'-ynyl)-1,4-bis(pent-4'-enyloxy)benzene | 925900-89-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2,5-bis(hex-1'-ynyl)-1,4-bis(pent-4'-enyloxy)benzene
• 英文别名: 1,4-Bis(hex-1-ynyl)-2,5-bis(pent-4-enoxy)benzene
• CAS: 925900-89-6
• 化学式: C₂₈H₃₈O₂
• 分子量: 406.609
• InChiKey: ZASVPGARXGUAKH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  30
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,5-bis(hex-1'-ynyl)-1,4-bis(pent-4'-enyloxy)benzene 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 二氯甲烷 为溶剂， 反应 22.0h， 以75%的产率得到6,13-bis(1'-butylethenyl)-2,3,4,9,10,11-hexahydro-1,8-dioxabenzo[1,2-b:4,5-b']-dicyclooctene
  参考文献：
  名称：

  An efficient synthesis of fused tricycles with a benzene core via intramolecular double ring-closing enyne metathesis

  摘要：

  A double enyne metathesis reaction has been developed for the efficient synthesis of tricyclic products with a benzene core in good yields. By this protocol, bisannulated benzenes with different ring sizes may he simultaneously constructed from the corresponding precursors in just 'one shot'. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2006.11.016
• 作为产物：
  描述：

  1,4-Dibrom-2,5-diacetoxybenzol 在 bis-triphenylphosphine-palladium(II) chloride sodium hydroxide 、 copper(l) iodide 、 potassium carbonate 、 三乙胺 作用下， 以 四氢呋喃 、 甲醇 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 47.33h， 生成 2,5-bis(hex-1'-ynyl)-1,4-bis(pent-4'-enyloxy)benzene
  参考文献：
  名称：

  An efficient synthesis of fused tricycles with a benzene core via intramolecular double ring-closing enyne metathesis

  摘要：

  A double enyne metathesis reaction has been developed for the efficient synthesis of tricyclic products with a benzene core in good yields. By this protocol, bisannulated benzenes with different ring sizes may he simultaneously constructed from the corresponding precursors in just 'one shot'. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2006.11.016

文献信息

• An efficient synthesis of fused tricycles with a benzene core via intramolecular double ring-closing enyne metathesis
  作者：Zhiqiang Liang、Shengming Ma、Jihong Yu、Ruren Xu

  DOI：10.1016/j.tet.2006.11.016

  日期：2007.1

  A double enyne metathesis reaction has been developed for the efficient synthesis of tricyclic products with a benzene core in good yields. By this protocol, bisannulated benzenes with different ring sizes may he simultaneously constructed from the corresponding precursors in just 'one shot'. (c) 2006 Elsevier Ltd. All rights reserved.