2-Methylidene-4-oxo-4-prop-2-enoxybutanoic acid | 5393-28-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Methylidene-4-oxo-4-prop-2-enoxybutanoic acid
• CAS: 5393-28-2
• 化学式: C₈H₁₀O₄
• 分子量: 170.165
• InChiKey: KAUVYPZCBVZESR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  衣康酸 、 烯丙醇 在 对甲苯磺酸 作用下， 反应 0.25h， 以70%的产率得到2-Methylidene-4-oxo-4-prop-2-enoxybutanoic acid
  参考文献：
  名称：

  Rama Devi; Rajaram, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000, vol. 39, # 4, p. 294 - 296

  摘要：

  DOI：

文献信息

• MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES
  申请人：Wabnitz Tobias

  公开号：US20110251119A1

  公开（公告）日：2011-10-13

  The present invention relates to a mixture comprising itaconic acid or an itaconic acid derivative and a primary amine of the formula (I) R—NH 2 (I) where the molar ratio of primary amine to itaconic acid or the itaconic acid derivative is in the range from 0.5:1 to 20:1, wherein the mixture comprises 50 mole percent or less of 4-carboxypyrrolidones of the formula (II), derivatives of the 4-carboxypyrrolidones of the formula (II) and 4-carbamidopyrrolidones of the formula (III) based on the itaconic acid used or the itaconic acid derivative used and in which R is a linear or branched saturated aliphatic radical having 1 to 24 carbon atoms or a saturated cycloaliphatic radical having 3 to 24 carbon atoms. The invention further provides for the use of the inventive mixtures for preparing 1,3-alkylmethylpyrrolidones and/or 1,4-alkylmethylpyrrolidones, and also a process for preparing 1,3-alkylmethylpyrrolidones and/or 1,4-alkylmethylpyrrolidones. In addition, the present invention relates to mixtures comprising 1,3-alkylmethylpyrrolidones and/or 1,4-alkylmethylpyrrolidones and 1,3-alkylmethylpyrrolidines, where the proportion of 1,3-alkylmethylpyrrolidines is in the range from 10 to 10 000 ppm, and to mixtures comprising 1,3-alkylmethylpyrrolidone and 1,4-alkylmethylpyrrolidone, wherein the molar ratio of 1,3-alkylmethylpyrrolidone to 1,4-alkylmethylpyrrolidone is in the range from 1:1 to 10:1.

  本发明涉及一种混合物，包括吡啶二酸或吡啶二酸衍生物和式（I）的一种主要胺，其中主要胺与吡啶二酸或吡啶二酸衍生物的摩尔比在0.5:1到20:1的范围内，其中混合物包括50摩尔％或更少的基于所使用的吡啶二酸或吡啶二酸衍生物的式（II）的4-羧基吡咯烷酮衍生物和4-羟基吡咯烷酮衍生物以及基于所使用的吡啶二酸或吡啶二酸衍生物的式（III）的4-氨基吡咯烷酮衍生物，其中R是具有1至24个碳原子的线性或支链饱和脂肪基或具有3至24个碳原子的饱和环脂基。该发明还提供了使用该混合物制备1,3-烷基甲基吡咯烷酮和/或1,4-烷基甲基吡咯烷酮的方法，以及制备1,3-烷基甲基吡咯烷酮和/或1,4-烷基甲基吡咯烷酮的方法。此外，本发明还涉及包含1,3-烷基甲基吡咯烷酮和/或1,4-烷基甲基吡咯烷酮和1,3-烷基甲基吡咯烷的混合物，其中1,3-烷基甲基吡咯烷的比例在10至10,000 ppm的范围内，并且涉及包含1,3-烷基甲基吡咯烷酮和1,4-烷基甲基吡咯烷酮的混合物，其中1,3-烷基甲基吡咯烷酮与1,4-烷基甲基吡咯烷酮的摩尔比在1:1到10:1的范围内。
• Compositions for preparing cross-linked polymers, paints and formed plastics
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0072065A2

  公开（公告）日：1983-02-16

  A class of polymer precursor materials, which, under appropriate conditions, react to form cross-linked polymers, is disclosed. These materials contain a backbone segment, such as polyacrylate, having pendant therefrom mono- or disubstituted olefinic groups, such as vinyl itaconate, having specific polymerization rates. This class of materials, especially when coupled with specifically-defined oxygen-activated catalyst systems, provide paint and plastic compositions which exhibit excellent film formation, strength and durability characteristics.

  本发明公开了一类聚合物前体材料，它们在适当的条件下反应形成交联聚合物。 这些材料包含一个主链段，如聚丙烯酸酯，其上悬挂有具有特定聚合速率的单取代或二取代烯烃基团，如依他肯酸乙烯酯。 这类材料，特别是与特定的氧活化催化剂系统结合使用时，可提供具有优异成膜性、强度和耐久性特征的涂料和塑料组合物。
• Method of catalyzing oxygen-initiated free-radical polymerization and catalysts used herein
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0072066A2

  公开（公告）日：1983-02-16

  A class of new oxygen-activated free-radical polymerization catalysts, comprising specifically-defined autoxidizable cyclic hydrocarbons together with co- bait(II) compounds. is disclosed. A method of catalyzing an oxygen-initiated free-radical polymerization reaction using these catalysts is also disclosed.

  本发明公开了一类新型氧活化自由基聚合催化剂，该催化剂由专门定义的可自氧化环烃和共饵（II）化合物组成。 本发明还公开了一种使用这些催化剂催化氧引发的自由基聚合反应的方法。
• Agents for preparing cross-linked polymers and polymerisable compositions and water based paint products containing such agents
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0099207A1

  公开（公告）日：1984-01-25

  A class of polymer precursor materials, which, under appropriate conditions, react to form cross-linked polymers, is disclosed. These materials contain a backbone segment, preferably a polyacrylate, and have pendant therefrom (1) reactive mono- or disubstituted olefinic groups, such as vinyl or allyl itaconate, and (2) water-solubilizing groups, such as the half ester of maleic acid. This class of materials, especially when combined with specifically-defined oxygen-activated catalyst systems, provides water-based paint compositions which exhibit film formation, strength and durability characteristics comparable to those of the best solvent-based paint formulations.

  本发明公开了一类聚合物前体材料，在适当的条件下，它们会反应形成交联聚合物。这些材料含有一个骨架段，最好是聚丙烯酸酯，并在其上悬挂有（1）活性单取代或二取代烯烃基团，如乙烯基或烯丙基衣康酸酯，以及（2）水溶性基团，如马来酸的半酯。这一类材料，特别是与特定的氧活化催化剂系统结合使用时，可提供水基涂料组合物，其成膜性、强度和耐久性可与最好的溶剂型涂料配方相媲美。
• Polyvinyl alcohol derivatives and crosslinked hydrogel contact lenses made therefrom
  申请人：CIBA-GEIGY AG

  公开号：EP0216074A2

  公开（公告）日：1987-04-01

  Polymers which are derivatives of a polyvinyl alcohol, having a weight average molecular weight of at least about 2,000, and containing from about 0.5 to about 90 percent, based on the number of hydroxyl groups in said polyvinyl alcohol, of units of the formula wherein R' and R2 are independently alkylene, arylene, a divalent cycloaliphatic group, arylenealkylene, alkylenearylene or arylenealkylenearylene, n is 0 or 1, A' is oxygen or NR', A is oxygen, NR" or a bivalent ureido group, R3 is hydrogen or methyl, R4 is hydrogen, methyl or COOR5, where R5 is hydrogen or lower alkyl, with the proviso that if R3 is methyl, R4 is hydrogen, R' and R" are independently hydrogen or lower alkyl, these polymers being an addition reaction product of units of formula I with from 0 to about 80 units of a vinylic monomer per unit of formula I, and crosslinked hydrogel contact lenses made therefrom and their preparation.

  聚合物是聚乙烯醇的衍生物，其重量平均分子量至少约为 2,000，根据所述聚乙烯醇中羟基的数量，含有约 0.5%至约 90%的式中单元。 其中 R' 和 R2 独立地为亚烷基、亚芳基、二价环脂族基团、亚芳基烷基、亚烷基芳基或亚芳基烷基芳基，n 为 0 或 1，A' 为氧或 NR'，A 为氧、NR "或二价脲基，R3 为氢或甲基，R4 为氢、甲基或 COOR5，其中 R5 为氢或低级烷基、但如果 R3 是甲基，R4 是氢，R'和 R "独立地是氢或低级烷基，这些聚合物是式 I 单位与每式 I 单位 0 至约 80 单位乙烯基单体的加成反应产物，以及由其制成的交联水凝胶隐形眼镜及其制备方法。