butyl 3-(butylamino)propanoate | 1001093-55-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: butyl 3-(butylamino)propanoate
• CAS: 1001093-55-5
• 化学式: C₁₁H₂₃NO₂
• mdl: MFCD24388468
• 分子量: 201.309
• InChiKey: SWIUCRILGXSFQH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.909
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  butyl 3-(butylamino)propanoate 在 氧气 、 manganese triacetate 、 sodium butanolate 作用下， 以 溶剂黄146 为溶剂， 反应 14.0h， 生成 6-butoxycarbonyl-8-butyl-1-hydroxy-4,4-diphenyl-8-aza-2,3-dioxabicyclo<4.3.0>nonan-9-one
  参考文献：
  名称：

  Nguyen, Van-Ha; Nishino, Hiroshi; Kurosawa, Kazu, Heterocycles, 1998, vol. 48, # 3, p. 465 - 480

  摘要：

  DOI：
• 作为产物：
  描述：

  丙烯酸丁酯 、 正丁胺 以 甲苯 为溶剂， 反应 20.0h， 以44%的产率得到butyl 3-(butylamino)propanoate
  参考文献：
  名称：

  使用可回收金催化剂进行活化烯烃的分子间单氢胺化和二氢胺化

  摘要：

  氯化金有机金属络合物和银盐的组合用于催化活化烯烃的分子间加氢胺化，即氮杂-迈克尔反应。研究了活化烯烃与氮底物的金催化反应，发现可以提供各种单氢胺化和二氢胺化产物，后者是罕见的和原始的。快速色谱后，金 NHC 催化剂可以作为氢氧化金 NHC 复合物回收。当与银盐结合时，金络合物再次导致活性加氢胺化催化剂。

  DOI：

  10.1002/ejoc.201200891

文献信息

• Intermolecular Mono- and Dihydroamination of Activated Alkenes Using a Recoverable Gold Catalyst
  作者：Florian Medina、Christophe Michon、Francine Agbossou-Niedercorn

  DOI：10.1002/ejoc.201200891

  日期：2012.11

  A combination of gold chloride organometallic complex and a silver salt was used to catalyze intermolecular hydroamination of activated alkenes, i.e aza-Michael reactions. The gold-catalyzed reactions of activated alkenes with nitrogen substrates were investigated and found to afford various mono- and dihydroamination products, the latter being rare and original. After flash chromatography, gold NHC

  氯化金有机金属络合物和银盐的组合用于催化活化烯烃的分子间加氢胺化，即氮杂-迈克尔反应。研究了活化烯烃与氮底物的金催化反应，发现可以提供各种单氢胺化和二氢胺化产物，后者是罕见的和原始的。快速色谱后，金 NHC 催化剂可以作为氢氧化金 NHC 复合物回收。当与银盐结合时，金络合物再次导致活性加氢胺化催化剂。
• Tandem bis-aza-Michael addition reaction of amines in aqueous medium promoted by polystyrenesulfonic acid
  作者：Vivek Polshettiwar、Rajender S. Varma

  DOI：10.1016/j.tetlet.2007.10.008

  日期：2007.12

  An efficient and environmentally benign tandem bis-aza-Michael addition of amines catalyzed by polystyrenesulfonic acid (PSSA) is described. This operationally simple high yielding microwave assisted synthetic protocol proceeded in water in the absence of any organic solvent. (c) 2007 Elsevier Ltd. All rights reserved.
• Horalek, Jiri; Svestka, Stefan; Krejcar, Emil, Collection of Czechoslovak Chemical Communications, 1988, vol. 53, # 12, p. 3149 - 3153
  作者：Horalek, Jiri、Svestka, Stefan、Krejcar, Emil、Novak, Jiri

  DOI：——

  日期：——
• Verfahren zur Herstellung von Azofarbstoffen
  申请人：BAYER AG

  公开号：EP0237910B1

  公开（公告）日：1990-05-30
• Sensors with improved properties
  申请人：Munoz Beth C.

  公开号：US20090260423A1

  公开（公告）日：2009-10-22

  A sensor or a sensor array connected to an electrical measuring apparatus is disclosed. In one embodiment, at least one sensor contains a layer of conductive modified particles which forms an electrical pathway or electrical circuit between two electrodes which are connected to an electrical measuring apparatus. In another embodiment, the first sensor contains at least one region of a nonconducting material and also a region that contains one or more modified particles. The modified particles are preferably conductive. An electrical path exists though the regions of the nonconducting material and the region containing the modified particles. The modified particles are conductive and more preferably are pigment particles such as modified carbon black, wherein the modified particles have attached at least one organic group. Alternatively, or in addition, the modified particle can be an aggregate having a carbon phase and a silicon-containing species phase and/or a metal-containing species phase wherein the aggregate optionally has attached at least one organic group. A sensor array for detecting an analyte in a fluid is also disclosed wherein each sensor emits a different response signature to an analyte wherein at least one of the sensors contains at least the modified particles as described above. Also, the present invention relates to a method for detecting the presence of an analyte in a fluid. The method involves contacting one or more sensors as described above with the analyte to generate a response and detecting the response with a detector that is operatively associated with each sensor in order to detect the presence of an analyte. Other advantages and embodiments are further described.