di(1-indanyl) ether | 199924-88-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: di(1-indanyl) ether
• 英文别名: di-indan-1-yl ether；Di-indan-1-yl-aether；Bis-(α-hydrindyl)-aether；indanyl ether；1-(2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydro-1H-indene
• CAS: 199924-88-4
• 化学式: C₁₈H₁₈O
• 分子量: 250.34
• InChiKey: YQRRFIKLPFQWAO-UHFFFAOYSA-N

物化性质

• 熔点：
  74 °C
• 沸点：
  386.1±31.0 °C(Predicted)
• 密度：
  1.15±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  di(1-indanyl) ether 生成 2,3-二氢-1H-茚-1-醇 、 茚
  参考文献：
  名称：

  The Preparation of Alpha and Beta Indanol and Some of Their Derivatives from Indene^1,2

  摘要：

  DOI：

  10.1021/ja01256a050
• 作为产物：
  描述：

  2,3-二氢-1H-茚-1-醇 在 mesoporous nickel-aluminosilicate nanocomposite 作用下， 以 甲苯 为溶剂， 反应 0.5h， 以98.8%的产率得到di(1-indanyl) ether
  参考文献：
  名称：

  Mesoporous Nickel–Aluminosilicate Nanocomposite: A Solid Acid Catalyst for Ether Synthesis

  摘要：

  介孔镍铝硅酸盐是一种通过溶胶-凝胶技术制备的固体酸催化剂，被用作非均相催化剂，通过醇的脱水缩合反应合成对称醚。制备的催化剂通过傅里叶变换红外光谱（FT-IR）、粉末X射线衍射（XRD）、扫描电子显微镜（SEM）、能量色散X射线分析（EDAX）、N2吸附-脱附分析、氨程序升温脱附（TPD）和X射线光电子能谱技术进行了表征。催化剂的存在促进了醚化反应在30分钟内进行。这些反应中形成的醚通过气相色谱（GC）进行定量，其中一些醚的鉴定通过核磁共振谱数据（NMR）得到了确认。

  DOI：

  10.1166/jnn.2013.7419

文献信息

• Organic compounds
  申请人：Palermo Gabriel Mark

  公开号：US20050234042A1

  公开（公告）日：2005-10-20

  Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula I

  抑制Smac蛋白与凋亡抑制蛋白(IAPs)结合的新化合物的化学式为I。
• Chlorides and Acetylacetonates of Transition Metals as Catalysts for the Oxidation of 1‐Indanol by Sodium Percarbonate
  作者：Samia Aït‐Mohand、Jacques Muzart、Stanislav Lunak

  DOI：10.1002/cber.19971301116

  日期：1997.11

  The screening of metal chlorides and metal acetylacetonates as catalysts for the oxidation of 1-indanol by sodium percarbonate (at reflux in 1,2-dichloroethane in the presence of small amounts of Adogen 464) has been carried out. The efficiency of the process depended on the nature of the transition metal and its oxidation state but, except for iron, was not greatly influenced by the nature of the

  已经进行了金属氯化物和金属乙酰丙酮化物的筛选，该催化剂用于通过过碳酸钠氧化1-茚满醇（在少量的Adogen 464存在下在1,2-二氯乙烷中回流）。该方法的效率取决于过渡金属的性质及其氧化态，但是除铁以外，不受配体性质的很大影响。使用PdCl 2，RhCl 3，RuCl 3，特别是MoO 2（acac）2作为催化剂，已经获得了良好的转化率和产率。
• Electrophoretic tag reagents comprising fluorescent compounds
  申请人：Aclara BioSciences, Inc.

  公开号：US20020146726A1

  公开（公告）日：2002-10-10

  Electrophoretic probes comprising fluorescent compounds as detection groups and mobility modifiers are disclosed for the multiplexed detection of the binding of, or interaction between, one or more ligands and target antiligands are provided. In one embodiment, detection involves the release of identifying tags as a consequence of target recognition. Target antiligands are contacted with a set of e-tag probes and the contacted antiligands are treated with a selected cleaving agent resulting in a mixture of e-tag reporters. Typically, uncleaved or partially cleaved e-tag probes are removed and the mixture of e-tag reporters is separated by any technique that provides for separation by mass or mass to charge ratio and the like and detected to provide for target identification.

  本发明提供了一种包含荧光化合物作为检测组和迁移修饰剂的电泳探针，用于多重检测一种或多种配体与目标抗配体之间的结合或相互作用。在一种实施方式中，检测涉及识别标签的释放，作为目标识别的结果。目标抗配体与一组e-tag探针接触，接触的抗配体经过选择的切割剂处理，导致e-tag报告物的混合物。通常，未切割或部分切割的e-tag探针被移除，e-tag报告物的混合物通过任何提供按质量或质量对电荷比分离的技术进行分离，并检测以提供目标识别。
• Compositions and methods employing cleavable electrophoretic tag reagents
  申请人：Aclara BioSciences, Inc.

  公开号：US20020142329A1

  公开（公告）日：2002-10-03

  Probe sets for the multiplexed detection of the binding of, or interaction between, one or more ligands and target antiligands are provided. Detection involves the release of identifying tags as a consequence of target recognition. The probe sets include electrophoretic tag probes or e-tag probes, comprising a detection region and a mobility-defining region called the mobility modifier, both linked to a target-binding moiety. Target antiligands are contacted with a set of e-tag probes and the contacted antiligands are treated with a selected cleaving agent resulting in a mixture of e-tag reporters and uncleaved and/or partially cleaved e-tag probes. The mixture is exposed to a capture agent effective to bind to uncleaved or partially cleaved e-tag probes, followed by electrophoretic separation. In a multiplexed assay, different released e-tag reporters may be separated and detected providing for target identification. The methods employ compositions comprising luminescent molecules such as, for example, fluorescent molecules, which are modified to provide for electrophoretic properties that differ for each modified luminescent molecule while maintaining substantially the same absorption, emission and quantum yield properties of the original luminescent molecule. The compositions may be cleavably linked to binding molecules to form the e-tag probes.

  提供了一种用于多重检测一种或多种配体与靶抗配体结合或相互作用的探针集。检测涉及到由于靶标识别而释放鉴别标记。该探针集包括电泳标记探针或e-tag探针，包括检测区域和称为迁移修饰因子的迁移定义区域，两者都连接到靶标结合基团。将靶抗配体与一组e-tag探针接触，并用选择的切割剂处理接触到的抗配体，导致e-tag报告物和未切割和/或部分切割的e-tag探针的混合物。混合物接触到有效结合到未切割或部分切割的e-tag探针的捕获剂，然后进行电泳分离。在多重检测中，不同的释放的e-tag报告物可以被分离和检测，从而实现靶标的识别。该方法采用包含发光分子的组合物，例如荧光分子，这些分子被修改以提供每种修改后的发光分子的电泳特性，同时保持原始发光分子的吸收、发射和量子产率特性基本相同。这些组合物可以与结合分子可剪切地连接以形成e-tag探针。
• [EN] INHIBITORS OF IAP<br/>[FR] INHIBITEURS D'IAP
  申请人：NOVARTIS AG

  公开号：WO2005097791A1

  公开（公告）日：2005-10-20

  Novel compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula (I).

  一种抑制Smac蛋白与抑制凋亡蛋白（IAPs）结合的新型化合物，其化学式为（I）。