Phosphoric acid 1-(2-allyloxy-phenyl)-vinyl ester diethyl ester | 583027-78-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: Phosphoric acid 1-(2-allyloxy-phenyl)-vinyl ester diethyl ester
• 英文别名: Diethyl 1-{2-[(prop-2-en-1-yl)oxy]phenyl}ethenyl phosphate；diethyl 1-(2-prop-2-enoxyphenyl)ethenyl phosphate
• CAS: 583027-78-5
• 化学式: C₁₅H₂₁O₅P
• 分子量: 312.303
• InChiKey: UMWFTWSHXCNRCM-UHFFFAOYSA-N

物化性质

• 沸点：
  393.3±34.0 °C(Predicted)
• 密度：
  1.114±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  54
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  Phosphoric acid 1-(2-allyloxy-phenyl)-vinyl ester diethyl ester 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 二氯甲烷 为溶剂， 以99%的产率得到2H-chromen-4-yl enol phosphate
  参考文献：
  名称：

  A convenient approach to cyclic enol phosphates via ring-closing metathesis

  摘要：

  A strategy employing the second generation Grubbs catalyst in order to facilitate the generation of a variety of cyclic enol phosphates, including 2H-chromen-4-yl, 1,2-dihydroquinolin-4-yl, 2H-thiochromen-4-yl, 2H-thiochromen-4-yl 1,1-dioxide, and benzofuran-2-yl enol phosphate scaffolds is described. This work represents the first case of an olefin metathesis reaction in which one of the groups participating in the metathesis event is an enol phosphate moiety. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)00873-6
• 作为产物：
  描述：

  2'-羟基苯乙酮 在 三苯基膦 、 lithium diisopropyl amide 、 偶氮二甲酸二乙酯 作用下， 以 四氢呋喃 为溶剂， 生成 Phosphoric acid 1-(2-allyloxy-phenyl)-vinyl ester diethyl ester
  参考文献：
  名称：

  A convenient approach to cyclic enol phosphates via ring-closing metathesis

  摘要：

  A strategy employing the second generation Grubbs catalyst in order to facilitate the generation of a variety of cyclic enol phosphates, including 2H-chromen-4-yl, 1,2-dihydroquinolin-4-yl, 2H-thiochromen-4-yl, 2H-thiochromen-4-yl 1,1-dioxide, and benzofuran-2-yl enol phosphate scaffolds is described. This work represents the first case of an olefin metathesis reaction in which one of the groups participating in the metathesis event is an enol phosphate moiety. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(03)00873-6

文献信息

• A convenient approach to cyclic enol phosphates via ring-closing metathesis
  作者：Alan Whitehead、Joel D. Moore、Paul R. Hanson

  DOI：10.1016/s0040-4039(03)00873-6

  日期：2003.5

  A strategy employing the second generation Grubbs catalyst in order to facilitate the generation of a variety of cyclic enol phosphates, including 2H-chromen-4-yl, 1,2-dihydroquinolin-4-yl, 2H-thiochromen-4-yl, 2H-thiochromen-4-yl 1,1-dioxide, and benzofuran-2-yl enol phosphate scaffolds is described. This work represents the first case of an olefin metathesis reaction in which one of the groups participating in the metathesis event is an enol phosphate moiety. (C) 2003 Elsevier Science Ltd. All rights reserved.